Results 151 to 160 of about 86,474 (255)

Endocrine therapy‐induced cancer‐related fatigue in hormone‐dependent malignancies: Mechanisms, impact, and management strategies

Precision Medical Sciences, EarlyView.
Multipathway schematic of endocrine therapy–induced cancer‐related fatigue. Endocrine interventions trigger four interacting mechanisms—neuroendocrine dysregulation, systemic inflammation, energy‐metabolic failure, and psycho‐behavioral amplification—that culminate in the multidimensional CRF phenotype.
Jiajing Jiang, Jun Lu, Sen Qin, Ruzhou Chen, Qiuchen Zhang, Lvqi He, Yubei Li, Jingyao Yan   +7 more
wiley   +1 more source

Sacituzumab Tirumotecan Across Gynecologic Malignancies: One Target, Multiple Diseases. [PDF]

Curr Oncol Rep
Sofianidi AA, Panagodimou E, Kalampokas E, Georgakopoulos I, Zagouri F.   +4 more
europepmc   +1 more source

Dehydrocostus Lactone Suppresses Hepatocellular Carcinoma by Inhibiting Protein Tyrosine Kinase‐7 Mediated β‐Catenin Signaling

Phytotherapy Research, EarlyView.
Schematic summary of the experimentally supported mechanism of DHL in hepatocellular carcinoma. Dehydrocostus lactone (DHL), a sesquiterpene lactone derived from Aucklandia lappa, directly engages protein tyrosine kinase 7 (PTK7), as supported by molecular docking, CETSA, and DARTS assays.
Xiwen Fan, Junhui Li, Yu Qiao, Yuwen Zhong, Xuecheng Ge, Yaoshuai Zhang, Zishu Wang, Feng Qian, Weixin Ren   +8 more
wiley   +1 more source

Evaluation of Gynecological Mass Lesions Using Magnetic Resonance Imaging: An Observational Study. [PDF]

Cureus
Ghosh T, Choudhury S, Kumar A.
europepmc   +1 more source

Government funding for uterine cancer research lags behind rising incidence. [PDF]

Gynecol Oncol Rep
Mojdehbakhsh RP, Spencer RJ, Uczkowski NG, Godecker AL.   +3 more
europepmc   +1 more source

Challenging prior assumptions: coexistence of polycystic ovarian morphology and endometriosis on transvaginal ultrasound

Ultrasound in Obstetrics &Gynecology, EarlyView.
ABSTRACT Objective To investigate, using transvaginal ultrasound imaging, the overlap between polycystic ovarian morphology (PCOM) and endometriosis, and to explore demographic and clinical factors associated with their coexistence across endometriosis phenotypes. Methods This was a retrospective cohort study of consecutive patients undergoing advanced
P. Romeo, S. M. Freger, N. Kalani, A. Shishkina, S. Aharoni, R. Shetty, M. Leonardi   +6 more
wiley   +1 more source

Temporal Clustering of Endometrial Cancer and Hyperplasia in HRT Users with Unscheduled Bleeding: A Retrospective NHS Cohort Study. [PDF]

Curr Oncol
Abdelaziz MAM, Mohamed A, Olaleye A, Hesham N, Tasnim N, Ogundiran O, Sandison L, Sayed H, Juliana A.   +8 more
europepmc   +1 more source

Advent of NK3R Antagonists for the Treatment of Menopausal Hot Flushes: A Narrative Review

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT The menopause transition is marked by symptoms predominantly attributed to declining oestrogen levels. Approximately 80% of women experience associated symptoms, and 25% experience severe symptoms. The commonest are vasomotor symptoms (VMS), collectively referring to hot flushes and/or night sweats.
Aaran H. Patel, Aureliane Pierret, Edouard G. Mills, Alexander N. Comninos, Waljit S. Dhillo, Ali Abbara   +5 more
wiley   +1 more source

Decoding the 2023 FIGO Staging System in Endometrial Cancer: A Practical, Visually Guided Framework for Molecular Risk-Adapted Care Incorporating the 2025 Risk Group Update. [PDF]

Curr Oncol Rep
Abacjew-Chmylko A, Razghоnоva Y, Milosz P, Ciarka A, Peksa R, Klasa-Mazurkiewicz D, Wydra DG, Mіka A.   +7 more
europepmc   +1 more source

Risk of Cancer With Hormone Replacement Therapy: A Narrative Review

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Hormone replacement therapy (HRT) remains the cornerstone of menopausal symptom management, effectively alleviating vasomotor symptoms and genitourinary syndrome, whilst mitigating long‐term risks such as osteoporosis. However, despite an increasing body of evidence on the relative safety of HRT, earlier studies that demonstrated an increased ...
Gabriella Yongue, Zachary Nash, Vikram Talaulikar, Shibani Nicum   +3 more
wiley   +1 more source