Results 131 to 140 of about 97,686 (304)

The association between telomerase activity and expression of its RNA component (hTR) in breast cancer patients: the importance of DNase treatment [PDF]

Telomerase is a ribonucleoprotein enzyme that compensates for the telomere length shortening which occurs during the cell cycle. Telomerase activity has been detected in most tumours but not in somatic cells.
حسینی اصل, سید سعید, مدرسی, محمد حسین, عطری, مرتضی, سلحاب, محمد, مکبل, کفاه, مهدی پور, پروین   +5 more
core   +1 more source

Living at genetic risk: The patient experience of Lynch syndrome

International Journal of Cancer, EarlyView.
Abstract Lynch syndrome is a germline cancer predisposition syndrome caused by a variant in one of four genes. Lynch syndrome places individuals at significantly higher risk for a range of cancers, especially colorectal and endometrial. Depending on which gene is affected, the risk of ovarian, gastric, small bowel, pancreatic, biliary urothelial, brain,
Nicola Reents, Georgina Hoffmann, Kelly Kohut   +2 more
wiley   +1 more source

Contaminación química ambiental y sus efectos en salud: revisión bibliográfica [PDF]

, 2018
Memoria escrita del Trabajo de Fin de Grado. Curso 2017-2018. Facultad de Medicina. Universidad de Málaga. Entregada en mayo de 2018, expuesta en junio de 2018.Introducción.
Palacios Prados, Antonio
core  

Long‐term association of physical activity with survival by primary cancer treatment in endometrial cancer: The Alberta Endometrial Cancer Cohort Study

International Journal of Cancer, EarlyView.
What's New? Accumulating evidence suggests a beneficial role of physical activity in cancer. However, it is unclear whether associations between physical activity and cancer outcomes vary by cancer treatment. Based on more than 16 years of follow‐up data from a cohort of endometrial cancer survivors, this study reveals that associations between ...
Minsuk Oh, Ki‐Yong An, Dong Hoon Lee, Renée L. Kokts‐Porietis, Linda S. Cook, Christine M. Friedenreich, Justin Y. Jeon, Kerry S. Courneya   +7 more
wiley   +1 more source

Endometrial Neoplasm [PDF]

, 2020
openaire   +1 more source

A multilevel perspective on MSH6‐associated Lynch syndrome: Integrating molecular, biological, and clinical insights

International Journal of Cancer, EarlyView.
Abstract Lynch syndrome (LS) is the most common hereditary colorectal cancer syndrome, caused by a germline pathogenic variant in one of the mismatch repair (MMR) genes. Among these, MSH6‐associated LS represents a distinct subtype with unique molecular and clinical characteristics.
Salwa Ben Yahia, Anne‐Sophie van der Werf‐'t Lam, Madalina Cabuta, Maartje Nielsen, Noah C. Helderman   +4 more
wiley   +1 more source

Adherens junction protein expression is associated with poor response to neoadjuvant FLOT chemotherapy and pro‐inflammatory tumor microenvironment in esophageal adenocarcinoma

International Journal of Cancer, EarlyView.
What's New? Esophageal adenocarcinoma (EAC) is an aggressive cancer with poor survival and variable response to perioperative chemotherapy. Although histopathological features correlate with outcomes, the relationship specifically between adherens junction (AJ) protein expression and treatment response in EAC remains uncertain.
Bastian Grothey, Heike Löser, Tillmann Bedau, Wolfgang Schröder, Christiane J. Bruns, Thomas Zander, Max Krämer, Reinhard Büttner, Alexander Quaas   +8 more
wiley   +1 more source

Benign Endometrial Neoplasm [PDF]

, 2020
openaire   +1 more source

Urokinase Plasminogen Activator Receptor‐Associated Protein (uPARAP) as a Potential Next Generation Molecular Target for Treatment of Gastrointestinal Stromal Tumors (GIST)

International Journal of Cancer, EarlyView.
A key component of the collagen internalization and lysosomal degradation cellular machinery, uPARAP may contribute to cancer progression. Here, the authors explored the expression of uPARAP in gastrointestinal stromal tumors using well‐annotated clinical patient samples and specimens from cell line‐ and patient‐derived xenografts.
Chao‐Chi Wang, Flavia Paternostro, Agnieszka Wozniak, Lore De Cock, Luna De Sutter, Kimberly Verbeeck, Ulla Vanleeuw, Daniël Gorgels, Che‐Jui Lee, Raf Sciot, Patrick Schöffski   +10 more
wiley   +1 more source

Sensitive Period Analysis of Adulthood BMI and Cancer Risk: An Individual Participant Data Meta‐Analysis of Over 720,000 Participants in the ABACus 2 Consortium

International Journal of Cancer, EarlyView.
Over a dozen cancers have been associated with excess body mass index, primarily in mid‐to‐late adulthood. Whether obesity‐related cancer risk differs across adulthood remains unclear. Using the Sensitive Periods Model and super‐landmarking approaches, this study found that higher BMI increased obesity‐related cancer risk across ages 30–65.
Nadin K. Hawwash, Matthew Sperrin, Glen P. Martin, Rashmi Sinha, Charles E. Matthews, Matthias B. Schulze, Anouk Hiensch, Pilar Amiano, Marian L. Neuhouser, Corinne E. Joshu, Elizabeth A. Platz, Heinz Freisling, Marc J. Gunter, Andrew G. Renehan   +13 more
wiley   +1 more source