Results 151 to 160 of about 93,286 (337)
International Journal of Cancer, EarlyView.What's New? PARP inhibitors are effective in patients with inactivating alterations in the BRCA1/2 genes across tumor types. However, the efficacy of PARP inhibitors in patients with other inactivated homologous recombination repair genes remains unclear. This knowledge gap and discrepancies in EMA/FDA approvals highlight the need for better biomarkers.
Ilse A. C. Spiekman +15 more
wiley +1 more source
International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 112-120, April 2025.Abstract Objective In the present study, a bidirectional two‐sample Mendelian randomization approach was utilized to explore potential causal relationships between mitochondrial DNA copy number (mtDNA‐CN) and ovary‐related reproductive disorders (ORRDs), including ovarian dysfunction, ovarian cyst, polycystic ovary syndrome (PCOS), premature ovarian ...
Ke Peng +4 more
wiley +1 more source
Pembrolizumab in programmed death ligand 1-positive endometrial cancer [PDF]
, 2017 BENEDETTI PANICI, Pierluigi +2 more
core +1 more source
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Objective To investigate the role of ST3 beta‐galactoside alpha‐2,3‐sialyltransferase 1 (ST3Gal1) in endometrial cancer (EC) progression and its potential as a therapeutic target to enhance the efficacy of antiangiogenic treatment. Methods ST3Gal1 expression and its clinical relevance were analyzed in EC tissues.
Chia‐Hao Liu +8 more
wiley +1 more source
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Objective To compare surgical and oncologic outcomes between conventional resectoscopic surgery and mechanical hysteroscopic tissue removal (mHTR) systems in high‐risk patients not suitable for standard surgery undergoing conservative treatment for multifocal endometrial atypical hyperplasia/endometrial intraepithelial neoplasia (EAH/EIN) or ...
Alessandro Arena +9 more
wiley +1 more source
The Value of DNA Quantitative Cytology Test for the Screening of Endometrial Cancer
Cancer Management and Research, 2019 Bao-hua Yang,1 Ming-xia Yu,1 Jun Xu,1 Yan Su,1 Zhi-hong Ai2 1Department of Obstetrics and Gynecology, Shanghai Minhang Central Hospital, Shanghai 201199, People’s Republic of China; 2Department of Obstetrics and Gynecology, Shanghai Jiao Tong ...
Yang B, Yu M, Xu J, Su Y, Ai Z
doaj
Surgical site infections and sepsis in gynecological surgery
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Despite advancements in infection control, surgical site infections (SSIs) and postoperative sepsis remain significant challenges in gynecological surgery, contributing to increased morbidity, mortality, and healthcare costs. In low‐income countries, circulatory failure due to septic shock leads to most deaths after surgery, with sepsis ...
Cristina Taliento +13 more
wiley +1 more source
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Background/aim This study evaluated cesarean section scar endometriosis (CSSE) characteristics and compared adipose‐ and muscle‐layer CSSEs. Materials and methods We analyzed 53 patients who underwent CSSE surgery between 2019‐2024, with 38 (71.7%) having adipose‐layer and 15 (28.3%) having muscle‐layer CSSE.
Emre Erdem Taş +3 more
wiley +1 more source
Malignant mixed Müllerian tumor
Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2018 Uterine carcinosarcomas or malignant mixed Müllerian tumors are rare neoplasms. They have an aggressive behavior and the prognosis depends mainly on the stage of the disease at the time of diagnosis. The progression of these tumors is unfavorable despite
Javier Martínez-Navarro +2 more
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Dienogest use and the risk of breast and gynecologic cancers: A nationwide population‐based study
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Objective To evaluate whether dienogest exposure is associated with the risk of breast, endometrial, or tubo‐ovarian cancer in women with endometriosis. Methods In this nationwide retrospective cohort study (January 2012 to December 2023), we used the Korean National Health Insurance Review & Assessment Service database. Women aged 20–49 years
Hoyol Jhang +4 more
wiley +1 more source