Results 161 to 170 of about 83,626 (295)
Cancer Science, EarlyView.CXCL1 secreted by M2 macrophages induced EMT of EC cells through the CXCR2/NF‐κB pathway; CXCR2 expression was predominantly observed in the epithelial compartment, whereas CXCL1 expression was primarily localized in the stromal region; Neutralization of M2 macrophage‐secreted CXCL1 and inhibiting the NF‐κB pathway can inhibit EC progression in vivo ...
Ruiqi Xia +4 more
wiley +1 more source
IL 15 enhances preclinical efficacy of anti-core 1 O-glycans monoclonal antibody NEO-201 against human endometrial and ovarian cancer. [PDF]
Front ImmunolHur J +11 more
europepmc +1 more source
Cancer Science, EarlyView.In this study, we investigated the predictive value of tumor mutational burden (TMB) for assessing the efficacy of pembrolizumab in a Japanese cohort. We analyzed real‐world data from 63,952 patients registered in the C‐CAT database who underwent comprehensive genomic profiling, and evaluated the therapeutic efficacy of pembrolizumab in 1899 of these ...
Tomoyo Yasuda +7 more
wiley +1 more source
Estrogen-Dependent Regulation of FDPS in the Mouse Uterus and Its Expression in Endometrial Cancer. [PDF]
Int J Mol SciSuh Y +8 more
europepmc +1 more source
Cancer Science, EarlyView.This study identifies downregulated autoantibodies in NSCLC and demonstrates their diagnostic and prognostic utility. Integrating proteome‐wide screening and large‐cohort validation, we highlight a novel biomarker class that enhances early detection and patient stratification.
Yihao Liang +7 more
wiley +1 more source
COX7A1-mediated mitochondrial dysfunction can induce ferroptosis in endometrial cancer cells. [PDF]
PLoS OneWu Q, Bai S, Song L, Han L, Wang P.
europepmc +1 more source
Cancer Science, EarlyView.We identified key endometrial cancer DNA methylation biomarkers (ZNF626, GRIA4, SPDYA) from cervical cells. The model achieved high endometrial cancer sensitivity and detected 92.86% of Stage I endometrial cancers using TCT samples. ABSTRACT Endometrial cancer, the most common gynecological malignancy with an annual increase of 1%–3%, lacks suitable ...
Yan Cai +10 more
wiley +1 more source
Feasibility and Safety of Robotic Para-Aortic Lymphadenectomy Using the hinotori™ Surgical Robot System: A First-in-Human Experience. [PDF]
CureusMabuchi S +4 more
europepmc +1 more source
SMURF1 Regulates CTCF‐HOXA10 Axis and Promotes Tumor Progression in Nasopharyngeal Carcinoma
Cancer Science, EarlyView.Our study showed that SMURF1 was significantly upregulated in nasopharyngeal carcinoma (NPC) and promoted tumor progression and SMURF1 promoted K48‐linked ubiquitination degradation of CTCF. ABSTRACT The aberrant upregulation of Homeobox A10 (HOXA10) has been implicated in the progression of nasopharyngeal carcinoma (NPC), but the mechanisms driving ...
Ying Jin +5 more
wiley +1 more source