Results 161 to 170 of about 93,286 (337)

Minimally invasive surgical treatment of recurrent endometrial carcinoma: A systematic review

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background While the role minimally invasive surgery (MIS) is established for primary endometrial carcinoma (EC), its feasibility in recurrent cases remains underexplored. Objective To systematically review the literature about MIS for EC recurrence.
Antonio Raffone   +12 more
wiley   +1 more source

The epidemiology and pathogenesis of uterine fibroids

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Uterine fibroids, or leiomyomas, are the most common benign tumors of the female reproductive tract, ultimately affecting a majority of women worldwide, primarily during their reproductive years. While their origin appears genetic, manifesting in monoclonal tumors, diverse features and mechanisms contribute to their growth and further ...
Malcolm G. Munro   +2 more
wiley   +1 more source

FIGO committee opinion: Environmental drivers of gynecologic and reproductive health

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract This FIGO committee opinion paper addresses the growing body of evidence linking environmental exposures to common gynecologic and reproductive conditions across the life course. From adolescence through menopause, women are exposed to a wide range of environmental toxicants, including endocrine‐disrupting chemicals, air pollutants, heavy ...
Nathaniel DeNicola   +9 more
wiley   +1 more source

Homoharringtonine suppresses acute myeloid leukemia progression by orchestrating EWSR1 phase separation in an m6A‐YTHDF2‐dependent mechanism

open access: yesiMeta, EarlyView.
Homoharringtonine (HHT), a clinically approved anti‐leukemic drug, directly binds the RNA‐binding protein EWSR1. HHT induces an allosteric conformational switch in the RNA recognition motif of EWSR1, driving self‐association and liquid–liquid phase separation (LLPS). The resulting condensates act as regulatory hubs that sequester the m6A reader YTHDF2,
Ting‐Ting Liu   +17 more
wiley   +1 more source

Ultrasound method in the diagnosis of ovarian neoplasms in patients with endometrial cancer

open access: diamond, 2016
М. А. Чекалова   +3 more
openalex   +2 more sources

New trend in molecular diagnostics: Insights from the tumor microenvironment

open access: yesInterdisciplinary Medicine, EarlyView.
The graphical abstract outline the key elements in TME‐based molecular diagnostics, including biomarker exploration, diagnostic methods, and diagnostic models. Source: Created with BioRender.com. Abstract Molecular diagnosis has revolutionized cancer precision medicine.
Baiyuan Fan   +3 more
wiley   +1 more source

Clinical Application of Positron Emission Tomography/Magnetic Resonance Imaging in Pelvic Malignant Tumors

open access: yesiRADIOLOGY, EarlyView.
The article reviews the application of positron emission tomography/magnetic resonance imaging (PET/MRI) in pelvic tumors such as endometrial cancer, cervical cancer, ovarian cancer, prostate cancer, and bladder cancer. We summarize the comparative studies on the clinical application between PET/CT and PET/MRI to highlight the advantages and ...
Hui Yang   +7 more
wiley   +1 more source

Phenothiazine Derivatives and Their Impact on the Apoptosis Processes: A Review

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Phenothiazine derivatives have been used for decades as antipsychotic drugs in multiple mental health and physical conditions treatment (schizophrenia, mania in bipolar disorder, and psychosis). Epidemiological studies have shown that people with schizophrenia are less likely to suffer from cancer, which indicates the ability of antipsychotics
Michał Otręba   +4 more
wiley   +1 more source

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