Results 201 to 210 of about 81,640 (291)

[Endometrial neoplasms. What to consider?].

open access: yesRevista da Associacao Medica Brasileira (1992), 2005
openaire   +1 more source

A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer

open access: yesThe FEBS Journal, EarlyView.
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou   +4 more
wiley   +1 more source

Adult granulosa cell tumours of the testis analogous to ovarian counterparts are exceptionally rare: analysis of a multicentric series and review of the literature

open access: yesHistopathology, EarlyView.
Assessment of twenty testicular AGCTs with two different next‐generation sequencing (NGS) panels reveals differences with ovarian AGCTs, including absence of hotspot FOXL2 variants. Aims Testicular adult granulosa cell tumours (AGCTs) are rare and show several clinical–pathological differences with their ovarian counterparts.
Costantino Ricci   +20 more
wiley   +1 more source

GREB1‐rearranged uterine tumour shares a common DNA methylation signature with ESR1‐rearranged UTROSCT

open access: yesHistopathology, EarlyView.
GREB1‐rearranged uterine tumours share DNA methylation profiles with UTROSCTs, supporting a close relationship. Despite differences in morphology and genomic complexity, their epigenetic similarity supports the inclusion of these tumours within the UTROSCT spectrum. Background and objectives GREB1‐rearranged uterine tumours encompass a group of uterine
Cheng‐Han Lee   +12 more
wiley   +1 more source

Dermatologic Features of Endocrine Tumor Syndromes—Systematic Review and Meta‐Analysis

open access: yesInternational Journal of Dermatology, EarlyView.
ABSTRACT Endocrine tumor syndromes, including multiple endocrine neoplasia types 1, 2A, and 2B (MEN1, MEN2A, MEN2B), Carney complex (CNC), and PTEN hamartoma tumor syndrome (PHTS), are hereditary conditions characterized by multisystem tumor development.
Sára Pálla   +8 more
wiley   +1 more source

Age, lifestyle, and disease affect ciliary transport in the human fallopian tube. [PDF]

open access: yesSci Rep
Neville C   +6 more
europepmc   +1 more source

Prevalence of DNA Mismatch Repair Deficiencies in Multiple Solid Tumor Types in China

open access: yesJournal of Evidence-Based Medicine, EarlyView.
ABSTRACT Aim Microsatellite instability (MSI) as a result of deficient deoxyribonucleic acid (DNA) mismatch repair (dMMR) is a key contributor to the development of tumors with a high mutation rate and cancer‐specific neoantigens. dMMR identification can be beneficial for selection of immune checkpoint inhibitor (ICI) therapy‐eligible patients.
Xiaohua Shi   +14 more
wiley   +1 more source

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