Results 81 to 90 of about 679 (269)
Serum paraoxonase 1 activity and protein N-homocysteinylation in primary human endometrial cancer
Tumor Biology, 2018 Paraoxonase 1 plays an important role in protection from oxidative stress and also decomposes homocysteine thiolactone, the toxic metabolite of homocysteine.
Krzysztof Gałczyński +5 more
doaj +1 more source
Sarcoma do Estroma Endometrial (SEE). Factores de prognóstico clínicos e patológicos.
Acta Médica Portuguesa, 1997 Endometrial Stromal Sarcomas are rare neoplasms, accounting for 0.2% of female genital tract malignancies. They occur predominantly in post menopausal women, although they can develop during the reproductive years or even in childhood. The most important
I Paiva +8 more
doaj +1 more source
Three-dimensional virtual histology of benign and malignant endometrial stromal neoplasms: a new perspective on why morphology matters [PDF]
, 2021 F. Kommoss +5 more
openalex +1 more source
Advanced Science, EarlyView.Tirzepatide, a dual GIP/GLP‐1 receptor agonist for diabetes, suppresses colorectal cancer growth by targeting glucose metabolism. It inhibits cancer cell proliferation, promotes apoptosis, and induces tumor regression. It reduces glucose uptake and destabilizes HIF‐1α for degradation to downregulate PFKFB3/PFK‐1 enzymes, thus contributing to the ...
Yikai Zhang +11 more
wiley +1 more source
Advanced Science, EarlyView.The research findings indicate that dimethyl itaconate (DI) alleviates Escherichia coli (E. coli) induced endometritis by modulating the gut microbiota and enriching the abundance of norank_f_Muribaculaceae, thereby increasing the production of guanosine.
Yuhang He +6 more
wiley +1 more source
Hierarchical Phenotyping and Graph Modeling of Spatial Architecture in Lymphoid Neoplasms [PDF]
arXiv, 2021 The cells and their spatial patterns in the tumor microenvironment (TME) play a key role in tumor evolution, and yet the latter remains an understudied topic in computational pathology. This study, to the best of our knowledge, is among the first to hybridize local and global graph methods to profile orchestration and interaction of cellular components.
arxiv
Advanced Science, EarlyView.The splicing factor PTBP3 promotes COX11 exon skipping, allowing gastric cancer organoids to evade cuproptosis. Antisense oligonucleotide drugs targeting PTBP3‐mediated COX11 alternative splicing, in combination with copper ionophores, promote cuproptosis in organoids, thereby providing a therapeutic approach for gastric cancer peritoneal metastasis ...
Yajing Zhou +11 more
wiley +1 more source
Gynecology Obstetrics & Reproductive Medicine, 2015 Aim of the paper is to investigate the suspicious role of HPV in synchronous endometrial and cervical carcinomas and to discuss the relation between HPV and endometrium epithelium.
Salih Taşkın +4 more
doaj
Studying the emergence of invasiveness in tumours using game theory [PDF]
, 2008 Tumour cells have to acquire a number of capabilities if a neoplasm is to become a cancer. One of these key capabilities is increased motility which is needed for invasion of other tissues and metastasis. This paper presents a qualitative mathematical model based on game theory and computer simulations using cellular automata.
arxiv +1 more source
Advanced Science, EarlyView.Wang et al. discover a novel lncRNA regulator of mutant oncoprotein which prevents AKT1E17K dephosphorylation. SVIL‐AS1 overexpression correlates with poor prognosis of breast cancer patients. It interacts with AKT1E17K protein and impedes PP2A holoenzyme from dephosphorylating AKT1 by blocking the binding of the regulatory subunit PPP2R2A to AKT1 ...
Jingyi Wang +8 more
wiley +1 more source