A Case Report of a Severely Aggressive Uterine Sarcoma at an Unusual Age [PDF]
Uterine sarcomas are very unique tumors with mesodermial origin and accounting for 2-6% of uterine cancers. In general, uterine sarcomas are the most malignant tumors of the uterus.
zahra honarvar, Mohades Peydayesh
doaj
Fibroblast growth factor receptor signaling in hereditary and neoplastic disease: biologic and clinical implications. [PDF]
Fibroblast growth factors (FGFs) and their receptors (FGFRs) are transmembrane growth factor receptors with wide tissue distribution. FGF/FGFR signaling is involved in neoplastic behavior and also development, differentiation, growth, and survival.
Helsten, Teresa+2 more
core +2 more sources
Endometrial Stromal Nodule: Report of a Case
Endometrial stromal nodule (ESN) is the least common of the endometrial stromal tumors. They are rare neoplasms which are diagnosed in most instances by light microscopy. Although such nodules are benign, hysterectomy has been considered the treatment of
F. Z. Fdili Alaoui+6 more
doaj +1 more source
Long-term results of a multicenter SAKK trial on high-dose ifosfamide and doxorubicin in advanced or metastatic gynecologic sarcomas [PDF]
Background: Dose intensive chemotherapy has not been tested prospectively for the treatment of gynecologic sarcomas. We investigated the antitumor activity and toxicity of high-dose ifosfamide and doxorubicin, in the context of a multidisciplinary ...
Cerny, T.+8 more
core
A Case of Malignant Low Grade Endometrial Stromal Sarcoma and Review of The Literature
Low grade endometrial stromal sarcoma is a rare pelvic malignancy that arises from the endometrium. This article describes the morphological features of one such tumour discovered as finding in a hysterectomy specimen of a 32-year lady with a clinical ...
Amrish N Pandya+2 more
doaj
Identification of an EPC2-PHF1 fusion transcript in low-grade endometrial stromal sarcoma
Recurrent chromosomal translocations leading to gene fusion formation have been described in uterine sarcomas, including low-grade endometrial stromal sarcoma (LG-ESS).
M. Brunetti+5 more
semanticscholar +1 more source
Dose-response effect of interleukin (IL)-1β, tumour necrosis factor (TNF)-α, and interferon-γ on the in vitro production of epithelial neutrophil activating peptide-78 (ENA-78), IL-8, and IL-6 by human endometrial stromal cells [PDF]
Purpose: The production of epithelial neutrophil activating peptide-78 (NA-78) and the interleukins IL-8 and IL-6 by endometrial stromal cells is stimulated by pro-inflammatory interleukin-1 (IL-1) and tumour necrosis factor-α (TNF-α).
Bersinger, Nick+4 more
core
Recurrent Endometrial Stromal Sarcoma: Treatment with a Progestin and Gonadotropin Releasing Hormone Agonist [PDF]
Endometrial stromal sarcoma (ESS) formerly classified as low-grade endometrial stromal sarcoma is a rare uterine malignancy with a good prognosis despite a tendency to recur.
DiSaia, Philip John+1 more
core +4 more sources
Reporting clinical cases of high-grade endometrial stromal sarcoma tumors is essential for a better understanding of their natural course and for the development of appropriate diagnostic and treatment strategies.
Faraz Mahdizadeh+3 more
doaj +1 more source
Uterine sarcoma is a very aggressive and highly lethal disease. Even after a comprehensive staging surgery or en block cytoreduction surgery followed by multimodality therapy (often chemotherapy and/or radiation therapy), many patients relapse or present
Ming-Shyen Yen+94 more
doaj +1 more source