Results 61 to 70 of about 34,989 (268)

Endometrial Stromal Nodule: A Rarity and a Pathological Challenge

Case Reports in Obstetrics and Gynecology, 2015
Endometrial stromal tumors are rare, and endometrial stromal nodule is the least common. In the region of Middle Jutland, Denmark, only two cases are reported since 1995.
Camilla Skovvang Borg, Peter Humaidan, Hanne Noer, Huda Galib Majeed   +3 more
doaj   +1 more source

A remarkable response to pazopanib, despite recurrent liver toxicity, in a patient with a high grade endometrial stromal sarcoma, a case report

BMC Cancer, 2018
Background Pazopanib is an oral tyrosine kinase inhibitor registered for metastatic renal cell carcinoma and soft tissue sarcoma. Liver toxicity is a common side effect for this class of agents.
Arie J. Verschoor, Fabiënne A. R. M. Warmerdam, Tjalling Bosse, Judith V. M. G. Bovée, Hans Gelderblom   +4 more
doaj   +1 more source

The utility of the 3D imaging software in the macroscopic rendering of complex gynecologic specimens [PDF]

, 2015
A new generation of three dimensional (3D) imaging software for the anatomical rendering of the human body, and related surgical pathologies, is postulated.
BARBOLINI, Giuseppe, MAIORANA, Antonino, PALMIERI, Beniamino, Piscioli, F, Pusiol, T, Roncati, L, Scialpi, M   +6 more
core   +1 more source

Nuclear Mechanotransduction Across the Metastatic Cascade: Decoding Spatiotemporal Heterogeneity in Cancer Dissemination

Advanced Science, EarlyView.
Tumor metastasis results from complex interactions between cancer cells and mechanical microenvironments. We propose a “nucleus‐centered, cross‐stage mechanical signal decoding” model, highlighting how nuclear mechanosensors interpret forces at different stages.
Linqi Song, Jingyang Liu, Xue Wang, Minpu Zhang, Changgang Sun   +4 more
wiley   +1 more source

The Importance of the Study of the Hemodynamics of the Uterine Tumors by the Method of Dopplerometry in the Two- and Three-dimensional Echography Modes for Differential Diagnostics of Simple, Proliferating Leiomyomas and Uterine Sarcomas (Review of Litera [PDF]

, 2018
The article analyzes modern literature data on the importance of studying the hemodynamics of uterine tumors with dopplerometry in two - and three - dimensional regimens of echography for differential diagnosis of simple proliferating leiomyomas and ...
Sukhin, V. (Vladyslav), Tamm, T. (Tamara), Yakovenko, E. (Elena), Yakovenko, K. (Kirill)   +3 more
core   +2 more sources

Cold atmospheric plasma‐mediated tumor microenvironment remodeling for cancer treatment

BMEMat, EarlyView.
Schematic presentation of CAP‐mediated TME remodeling. This review summarizes recent efforts in cold atmospheric plasma (CAP) application in cancer treatment, highlighting the anticancer potential of CAP, molecular mechanisms, and future perspectives for further improvement and clinical translation.
Israr Khan, Qiujie Fang, Cao Fei, Ziyuan Wang, Zhaowei Chen, Guojun Chen, Zhiming Xu, Shu Xu, Zhitong Chen   +8 more
wiley   +1 more source

A rare case report of high-grade endometrial stromal sarcoma in a seemingly healthy uterus of a young patient – Optimally managed by minimally access surgery

Indian Journal of Medical and Paediatric Oncology, 2019
Endometrial stromal sarcomas (ESSs) are a rare entity, constituting 10% of all uterine sarcomas and 0.2% of all uterine malignancies. We report a very rare case of high-grade endometrial stromal sarcoma in a 34-year-old female with fibroids uterus ...
Kanika Jain, Debasis Dutta, Kanika Chopra, Pallav Gupta   +3 more
doaj   +1 more source

Disseminated Endometriosis and Low-Grade Endometrioid Stromal Sarcoma in a Patient with a History of Uterine Morcellation for Adenomyosis

Case Reports in Obstetrics and Gynecology, 2020
Morcellation of benign uterine tumors allows for removal of the tumors via minimally invasive laparoscopic procedures. However, in rare cases, morcellation has been associated with upstaging of unexpected malignancies.
Daniel P. Stefanko, Ramez Eskander, Omonigho Aisagbonhi   +2 more
doaj   +1 more source

Potential Targets' Analysis Reveals Dual PI3K/mTOR Pathway Inhibition as a Promising Therapeutic Strategy for Uterine Leiomyosarcomas-an ENITEC Group Initiative [PDF]

, 2017
Purpose: Uterine sarcomas are rare and heterogeneous tumors characterized by an aggressive clinical behavior. Their high rates of recurrence and mortality point to the urgent need for novel targeted therapies and alternative treatment strategies. However,
Amant, Frederic, Annibali, Daniela, Bosse, Tjalling, Brinkhuis, Mariel, Carpen, Olli, Colas, Eva, Coosemans, An, Cuppens, Tine, Dundr, Pavel, Garcia-Jimenez, Angel, Gomme, Ellen, Haybaeck, Johannes, Hermans, Els, Huvila, Jutta, Kruitwagen, Roy P. M., Mallmann, Michael R., Massuger, Leonardus F., Mestdagh, Carole, Mints, Miriam, Moerman, Philippe, Moinfar, Farid, Salvesen, Helga B., Stukan, Maciej, ter Haar, Natalja, Thomas, Debby, Trovik, Jone, Van de Vijver, Koen, Verbist, Godelieve, Wardelmann, Eva, Zikan, Michal, Zweemer, Ronald P.   +30 more
core   +2 more sources

Urokinase Plasminogen Activator Receptor‐Associated Protein (uPARAP) as a Potential Next Generation Molecular Target for Treatment of Gastrointestinal Stromal Tumors (GIST)

International Journal of Cancer, EarlyView.
A key component of the collagen internalization and lysosomal degradation cellular machinery, uPARAP may contribute to cancer progression. Here, the authors explored the expression of uPARAP in gastrointestinal stromal tumors using well‐annotated clinical patient samples and specimens from cell line‐ and patient‐derived xenografts.
Chao‐Chi Wang, Flavia Paternostro, Agnieszka Wozniak, Lore De Cock, Luna De Sutter, Kimberly Verbeeck, Ulla Vanleeuw, Daniël Gorgels, Che‐Jui Lee, Raf Sciot, Patrick Schöffski   +10 more
wiley   +1 more source