Influence of Cancer-Associated Endometrial Stromal Cells on Hormone-Driven Endometrial Tumor Growth [PDF]
Hormones and Cancer, 2015 Cancer-associated fibroblasts have been shown to inhibit or stimulate tumor growth depending on stage, grade, and tumor type. It remains unclear, however, the effect of endometrial-cancer-associated fibroblasts on hormone-driven responses in endometrial cancer. In this study, we investigated the effect of normal and cancer-associated stromal cells from
M J, Pineda, Z, Lu, D, Cao, J J, Kim
openaire +2 more sources
Role for growth regulation by estrogen in breast cancer 1 (GREB1) in hormone-dependent cancers [PDF]
, 2018 Sex hormones play important roles in the onset and progression of several cancers, such as breast, ovarian, and prostate cancer. Although drugs targeting sex hormone function are useful in treating cancer, tumors often develop resistance.
Cheng, Meng +2 more
core +2 more sources
Metformin as a Therapeutic Target in Endometrial Cancers. [PDF]
, 2018 Endometrial cancer is the most common gynecologic malignancy in developed countries. Its increasing incidence is thought to be related in part to the rise of metabolic syndrome, which has been shown to be a risk factor for the development of ...
Johnson, Jennifer +6 more
core +2 more sources
Endometrial Stromal Sarcoma Recurrence in the Caecum
Case Reports in Surgery, 2018 Endometrial stromal sarcomas of uterus are quite rare. Most of the recurrences in these tumors are seen in the pelvis. However, extrapelvic recurrences and metastases to other parts are quite unusual.
Nisar A. Chowdri +5 more
doaj +1 more source
Sarcoma de estroma endometrial. Estudio clinicopatológico e inmunofenotípico de 5 casos [PDF]
, 2007 Introducción: El sarcoma de estroma endometrial uterino es un tumor muy poco frecuente con una incidencia de 0,4 -3,4 por 100.000 mujeres, comprende menos del 1% de tumores malignos ginecológicos y el 2-5% de tumores malignos uterinos, siendo el tercer ...
Llombart Bosch, Antonio +4 more
core +1 more source
Cyclin D1 and p16INK4 positive endometrial stromal sarcoma: A case report with new insights
Indian Journal of Pathology and Microbiology, 2014 Endometrial stromal sarcoma (ESS) has a wide histopathological spectrum with CD10 as its diagnostic marker. Recently, few non-conventional ESSs have been identified that lack diffuse CD10 expression. A 46-year-old, perimenopausal lady referred to us with
Bharat Rekhi, Priyal Motghare
doaj +1 more source
Primary ovarian endometrioid stromal sarcoma presenting with reno-ureteral colic
BMC Women's Health, 2022 Background Endometrioid Stromal Sarcomas are an infrequent group of mesenchymal tumors that we must take into account in the differential diagnosis despite representing only 0.2% of tumors of the female genital tract, as they can go unnoticed until ...
Ana Isabel Bueno Moral +5 more
doaj +1 more source
Frontiers in Immunology, 2022 Endometrial stromal tumor (EST) is an uncommon and unusual mesenchymal tumor of the uterus characterized by multicolored histopathological, immunohistochemical, and molecular features. The morphology of ESTs is similar to normal endometrial stromal cells
Youngah Kim +4 more
doaj +1 more source
Delayed menopause due to granulosa cell tumor of the ovary
Journal of Mid-Life Health, 2011 A 52-year-old patient presented with complaints of menorrhagia. Endometrial biopsy revealed simple hyperplasia of the endometrium. Total abdominal hysterectomy with bilateral oophorectomy was carried out.
Bhushan Murkey +3 more
doaj +1 more source
Clinicopathological and molecular markers associated with prognosis and treatment effectiveness of endometrial stromal sarcoma: a retrospective study in China [PDF]
, 2013 PURPOSE: To evaluate the clinicopathological and immunophenotypic characteristics of endometrial stromal sarcoma (ESS) in China. METHODS AND MATERIALS: Seventy-two consecutive ESS cases treated between 1995 and 2009 were retrospectively reviewed. RESULTS:
Jia-xin Lin +7 more
core +1 more source