Results 31 to 40 of about 60,149 (206)

HPV infection and endometrial polyps: insights from a case-control study

BMC Women's Health
Background Endometrial polyps are common benign lesions characterized by localized overgrowths of endometrial tissue within the uterine cavity. The etiology and pathogenesis of these polyps remain unclear.
Leila Nazari, Mansoureh Vahdat, Samaneh Rokhgireh, Shahla Chaichian, Abolfazl Mehdizadehkashi, Zahra Aminzade, Roya Derakhshan   +6 more
doaj   +1 more source

New Insights in Pathogenesis of Endometriosis

Frontiers in Medicine, 2022
Endometriosis is a gynecological disease characterized by the growth of endometrial glands and stroma outside the uterine cavity. The incidence of the disease is very high, there are currently no reliable early diagnostic tests, the therapies are only ...
Pietro G. Signorile, Rosa Viceconte, Alfonso Baldi   +2 more
doaj   +1 more source

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

Molecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński, Krzysztof Pastuszak, Anna Samelak‐Czajka, Zuzanna Cemka, Paulina Jackowiak, Tomasz Stefaniak, Sylwia Łapińska‐Szumczyk, Jacek Jassem, Anna J. Żaczek, Matthew T. Rondina, Myron G. Best, Sjors G. J. G. In 't Veld, Anna Supernat   +12 more
wiley   +1 more source

Intraoperative complications during gender-affirming laparoscopic hysterectomy in transgender men receiving testosterone: a case series

BMC Surgery
Background Laparoscopic hysterectomy is a core component of gender-affirming care for transgender men. However, long-term testosterone therapy can lead to anatomical and tissue changes that increase the complexity of pelvic surgery. Objective To describe
Samaneh Rokhgireh, Sara Norouzi, Roya Derakhshan, Neda Hashemi, Maryam Pourbarghi, Zahra Salehi   +5 more
doaj   +1 more source

Proposals for the #Enzian addendum and update: an international expert survey for item generation

Facts, Views & Vision in ObGyn
Background: Accurate and standardised characterisation of endometriosis extent is essential for patient counselling regarding pain and fertility outcomes, surgical planning, multidisciplinary communication, and clinical research.
Milena Petrovic, Jörg Keckstein, Mohamed Mabrouk, Ertan Saridogan, Mario Malzoni, Gernot Hudelist   +5 more
doaj   +1 more source

Antiapoptotic and antioxidative effects of cerium oxide nanoparticles on the testicular tissues of streptozotocin-induced diabetic rats: An experimental study

International Journal of Reproductive BioMedicine, 2021
Background: Cerium dioxide nanoparticles (CNPs) due to the antidiabetic and antioxidant activities are proposed for the treatment of oxidative stress-associated diseases.
Torab Solgi, Iraj Amiri, Sara Soleimani Asl, Massoud Saidijam, Banafsheh Mirzaei Seresht, Tayebe Artimani   +5 more
doaj   +1 more source

An Injectable ROS‐Responsive Nanozyme Hydrogel Regulates the Uterine Microenvironment to Prevent Intrauterine Adhesions

Advanced Science, EarlyView.
The injectable CeTA@GPP hydrogel is administered via intrauterine injection, forming a protective barrier. In the high ROS inflammatory microenvironment of injured endometrium, boronate ester cleavage triggers responsive CeTA release and local enrichment.
Peixian Cheng, Jian Song, Yuxin Li, Ming Chen, Zeshen Liang, Binyao Qiu, Xuemin Liu, Xuetao Shi, Yong Fan   +8 more
wiley   +1 more source

LncRNA FLJ20021 Restrains Fibroblast Senescence and Matrix Remodeling in Pelvic Organ Prolapse by Promoting XRCC6‐Dependent ADI1 Transcription

Advanced Science, EarlyView.
FLJ20021 interacts with XRCC6 to regulate ADI1 transcription and downstream cellular phenotypes in hUSLFs. Reduced FLJ20021 in POP is associated with lower ADI1, increased apoptosis, senescence, and an ECM‐degrading marker profile. Conversely, FLJ20021 overexpression enhances XRCC6‐dependent ADI1 expression, reduces apoptosis and senescence, and shifts
YanFeng Yang, BingJie Rui, GuangHai Rui, YiNan Duan, Ji Hyang Kim   +4 more
wiley   +1 more source

CGRP neuropeptide levels in patients with endometriosis-related pain treated with dienogest: a comparative study

BMC Women's Health
Background and objective Endometriosis (EM) involves the peripheral nervous system and causes chronic pain. Sensory nerves innervating endometriotic lesions contribute to chronic pain and influence the growth phenotype by releasing neurotrophic factors ...
Shahla Chaichian, Ziba Dehghan Firoozabadi, Samaneh Rokhgireh, Kobra Tahermanesh, Abolfazl Mehdizadeh Kashi, Azam Govahi, Sara Minaeian, Mehdi Mehdizadeh, Marziyeh Ajdary   +8 more
doaj   +1 more source

ATOPE study protocol: a randomised controlled trial comparing cystectomy and plasma vapourisation in endometriomas under 6 cm, with an observational arm for sclerotherapy in larger cysts

BMJ Open
Introduction The Ablative Technique Options for Preserving fertility in Endometrioma study is a prospective, monocentric clinical study that combines a randomised controlled trial comparing cystectomy and plasma vapourisation for endometriomas measuring ...
Benjamin Merlot, Horace Roman, Adrien Crestani, Isabella Chanavaz Lacheray, Thomas Dennis, Paul-Henri Goualard   +5 more
doaj   +1 more source