Results 61 to 70 of about 230,438 (387)

Organochlorine pesticides exposure & preterm birth [PDF]

, 2016
Commento su invito ad uno studio su esposizione fetale a composti ...
Fuggetta, Eliana, Porpora, Maria Grazia, Resta, Serena   +2 more
core   +3 more sources

Recent advances in understanding and managing chronic pelvic pain in women with special consideration to endometriosis [PDF]

, 2020
Chronic pelvic pain (CPP) in women is defined variably, but for clinical use it is cyclical or non-cyclical pain of at least 3-6 months' duration. It has major impacts on individuals and society. There are both structural and idiopathic causes.
Ball, E., Khan, K. S.
core   +1 more source

Targeting Itga8 Mitigates Neurogenic Bladder Fibrosis Driven by Trem2⁺ Macrophage‐Derived Fn1 via FAK/RhoA/ROCK Signaling

Advanced Science, EarlyView.
Normal bladders exhibit quiescent fibroblasts/macrophages, whereas neurogenic bladders show acute‐phase Itga8⁺ fibroblast expansion driven by Trem2⁺ macrophage‐secreted Fn1, which activates FAK/RhoA/ROCK signaling, promotes cytoskeletal remodeling, and upregulates pro‐fibrotic genes.
Jiaxin Wang, Siyuan Wang, Lida Ren, Xinqi Liu, Lei Zhang, Peng Hu, Wenchao Xu, Shuaixiang Zheng, Jihong Liu, Qing Ling   +9 more
wiley   +1 more source

Macrophages and small extracellular vesicle mediated-intracellular communication in the peritoneal microenvironment: Impact on endometriosis development

Frontiers in Reproductive Health, 2023
Endometriosis is an inflammatory disease that is defined as the growth of endometrium-like tissue outside the uterus, commonly on the lining of the pelvic cavity, visceral organs and in the ovaries. It affects around 190 million women of reproductive age
Yifan Wang, Rebecca A. Dragovic, Erin Greaves, Christian M. Becker, Jennifer H. Southcombe   +4 more
doaj   +1 more source

A polymorphism in a let-7 microRNA binding site of KRAS in women with endometriosis. [PDF]

, 2012
Endometriosis is found in 5-15% of women of reproductive age and is more frequent in relatives of women with the disease. Activation of KRAS results in de novo endometriosis in mice, however, activating KRAS mutations have not been identified in women ...
Chan, Elcie, Flores, Idhaliz, Grechukhina, Olga, Massasa, Efi, Paranjape, Trupti, Petracco, Rafaella, Popkhadze, Shota, Taylor, Hugh S, Weidhaas, Joanne B   +8 more
core   +1 more source

The Burden of Endometriosis on Women’s Lifespan: A Narrative Overview on Quality of Life and Psychosocial Wellbeing

International Journal of Environmental Research and Public Health, 2020
Endometriosis is a chronic, inflammatory disease affecting more than 170 million women worldwide and up to 10% of women of reproductive age. As a consequence of inflammatory reaction and infiltration of anatomic structures, endometriosis can cause “pain ...
L. Della Corte, C. Di Filippo, Olimpia Gabrielli, Sabrina Reppuccia, V. L. La Rosa, R. Ragusa, M. Fichera, Elena Commodari, G. Bifulco, P. Giampaolino   +9 more
semanticscholar   +1 more source

A Biomarker‐Driven Ovary–Endometrium Organ‐on‐a‐Chip Mimicking 3D Multicellular Complexity and Menstrual Cyclicity for Predicting Reproductive Toxicity

Advanced Science, EarlyView.
We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim, Eun‐kyung Min, Choon‐Mi Lee, Chan Hum Park, Byung‐Chul Oh, YunJae Jung, In‐Sun Hong   +6 more
wiley   +1 more source

CGRP neuropeptide levels in patients with endometriosis-related pain treated with dienogest: a comparative study

BMC Women's Health
Background and objective Endometriosis (EM) involves the peripheral nervous system and causes chronic pain. Sensory nerves innervating endometriotic lesions contribute to chronic pain and influence the growth phenotype by releasing neurotrophic factors ...
Shahla Chaichian, Ziba Dehghan Firoozabadi, Samaneh Rokhgireh, Kobra Tahermanesh, Abolfazl Mehdizadeh Kashi, Azam Govahi, Sara Minaeian, Mehdi Mehdizadeh, Marziyeh Ajdary   +8 more
doaj   +1 more source

Comparison of diagnostic values of transvaginal sonography with laparoscopic and histological results in the evaluation of uterosacral ligaments’ involvement in endometriosis patients

Caspian Journal of Internal Medicine, 2022
Background: Endometriosis is one of the most common gynecological disorders, which causes pain and reduces fertility. An accurate diagnostic technique would be helpful in the management of these patients preoperatively. The objective of this study was to
Pegah Kamkarfar, Roya Shahriyaripoor, Samaneh Rokhgireh, Seyed Reza Saadat Mostafavi, Shahla Chaichian, Abolfazl Mehdizadeh Kashi   +5 more
doaj  

Abdominal-pelvic pain in female patients with endometriosis - a review of the literature [PDF]

, 2018
Abdominal-pelvic pain is the dominant symptom in endometriosis, one of the most common pathologies that affect women, being also a multifactorial disorder.
Andronache, Liliana Florina, Badiu, Cristinel Dumitru, Grigorean, Valentin Titus, Mandu, Mihaela, Mastalier, Bogdan, Mehedintu, Claudia, Paduraru, Dan Nicolae, Pantea Stoian, Anca Mihaela, Sima, Marina Romina   +8 more
core   +1 more source