Results 61 to 70 of about 60,149 (206)

Menopause hormone therapy in women with cardiovascular risk factors or established ischemic heart disease: A joint FIGO and WHF position paper

International Journal of Gynecology &Obstetrics, EarlyView.
Integrated approach to menopausal hormone therapy in women with cardiovascular risk factors or established ischemic heart disease, from early treatment initiation and risk stratification to individualized therapy, multidisciplinary follow‐up, and health‐system recommendations.
Chiara Benedetto, Martha Gulati, Suvarna S. Khadilkar, Angela H. E. M. Maas, Federica Frezet, Gláucia Maria Moraes de Oliveira, Andrea R. Genazzani, Hema Divakar, Athena Poppas, on behalf of the World Heart Federation (WHF) and the International Federation of Gynecology and Obstetrics (FIGO)   +9 more
wiley   +1 more source

Occult serous tubal intraepithelial carcinoma and high‐grade serous carcinoma at risk‐reducing salpingo‐oophorectomy in BRCA1/2 carriers: A Czech two‐center cohort

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background Risk‐reducing salpingo‐oophorectomy is the standard intervention for prevention of tubo‐ovarian carcinoma in women with pathogenic BRCA1/2 variants, yet the optimal timing remains clinically challenging, particularly for BRCA2 carriers.
Olga Zikan Dubova, Lukas Dostalek, Michal Emingr, Munachiso Ndukwe, Michal Zikan   +4 more
wiley   +1 more source

Long‐term gastrointestinal function outcomes of women undergoing nerve‐vessel sparing segmental or full‐thickness discoid resection for deep colorectal endometriosis

Acta Obstetricia et Gynecologica Scandinavica
Introduction Patients undergoing colorectal surgery for symptomatic deep endometriosis may experience postoperative impairment of gastrointestinal function. However, there is limited information on long‐term follow‐up of this surgical sequela.
Daria Pashkunova, Ezgi Darici Kurt, Theresa Hudelist, Anna Rath, Attila Bokor, Gernot Hudelist   +5 more
doaj   +1 more source

Evaluating the diagnostic value of PLR and related hematologic parameters combined with CA‐125 for endometriomas

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Endometriosis is a chronic inflammatory disease, with inflammation relating to pathogenesis and staging. We compared inflammatory indices and clinical characteristics between patients with ovarian endometriomas and those with benign ovarian tumors to evaluate their diagnostic value and identify affordable blood markers for diagnosis ...
Pingping Su, Yanni Huang, Fenhong Kang, Lili Zhang, Lirui Yu, Hongli Liu   +5 more
wiley   +1 more source

Levator ani muscle enthesis‐related pain in patients with bladder pain syndrome: A retrospective cross‐sectional study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Interstitial cystitis/bladder pain syndrome is a chronic pelvic pain condition with heterogenous mechanisms. Levator ani muscle (LAM) enthesis‐related pain has been proposed as a musculoskeletal contributor to bladder pain symptoms. This study investigated whether LAM enthesis‐related pain is independent of cystoscopic glomerulation ...
Hong Ci Lim, Peng‐Hui Wang, Kuan‐Cheng Lin, Hung‐Yen Chin   +3 more
wiley   +1 more source

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

iNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid, Weirong Fan, Farah Nazir, Yixiang Xing, Tengchuan Jin   +4 more
wiley   +1 more source

The Role of High Cxcl11 Expression in Ovarian Dysfunction Through NF‐κB and AKT Pathways in a Thin Endometrium Mouse Model

iNew Medicine, EarlyView.
Thin endometrium upregulates Cxcl11, which polarizes ovarian macrophages via NF‐κB/AKT, impairing ovarian function. A new uter‐ovarian signaling axis is identified. ABSTRACT Objective Thin endometrium (TE) is a recognized cause of female infertility, primarily associated with impaired uterine receptivity.
Yulu Yang, Fei Tang, Zihan Meng, Yunxi Bao, Jujun Han, Xiaohua Jiang, Jianye Wang, Ying Wang, Zhaolian Wei   +8 more
wiley   +1 more source

Exploring vaginal microbiota–tissue resident stem cell crosstalk: VCAM1/Akt signaling ‐mediated enhancement of regenerative capacity

Interdisciplinary Medicine, EarlyView.
Vaginal microbiota‐derived secretory factors enhance the regenerative capacity of human endometrial stem cells by upregulating VCAM1 and activating PI3K/Akt signaling. This microbiota–stem cell crosstalk promotes self‐renewal, migration, multilineage differentiation, and metabolic reprogramming in vitro and in vivo, establishing a novel microbiota ...
Soo‐Rim Kim, Eun‐Kyung Min, Choon‐Mi Lee, Kun‐Hee Na, Chan Hum Park, YunJae Jung, Hwa‐Yong Lee   +6 more
wiley   +1 more source

Identification of a circulating immunological signature as a liquid biopsy approach for the diagnosis of endometriosis

Scientific Reports
Endometriosis is a chronic inflammatory disease characterized by ectopic endometrial tissue growth, causing pain and infertility. Diagnosis is often delayed due to reliance on imaging and invasive methods, highlighting the need for non-invasive ...
Alicia Hernández, Olivia Fernández-Medina, Paula Almellones Araiz, Verónica Terrón, Tamara Ruiz Martínez, Ana López Carrasco, Maria Luisa Juan Rodrigo, Eduardo López-Collazo, Carlos Del Fresno, Emanuela Spagnolo   +9 more
doaj   +1 more source

Transperineal Ultrasound in Chronic Pelvic Pain: A Systematic Review

Journal of Clinical Ultrasound, EarlyView.
Graphical abstract illustrating the systematic review process and highlighting key pelvic floor musculature (PFM) alterations detected by transperineal ultrasound (TPU) in patients with chronic pelvic pain (CPP) and associated conditions. These findings provide insights to enhance understanding and management of CPP.
Giulia Paoni Saccone, Noemi Tonti, Valeria Gangale, Maria Grazia Porpora, Federica Tomao, Violante Di Donato, Innocenza Palaia, Giusi Santangelo, Ludovico Muzii, Giuseppe Rizzo, Giorgia Perniola   +10 more
wiley   +1 more source