Results 101 to 110 of about 77,089 (218)

MLH1 p.His112Arg Variant Is Associated With Increased Cancer Susceptibility

International Journal of Cancer, EarlyView.
ABSTRACT Lynch syndrome, a prevalent hereditary cancer predisposition, is frequently caused by pathogenic variants in the MutL homolog 1 (MLH1) mismatch repair gene. However, a significant proportion of MLH1 missense variants remain classified as variants of uncertain significance (VUS), creating clinical ambiguity.
Amal Elfatih, Issam Tout, Najwa Ahmad Doha, Tala Abu Arja, Idris Mohammed, Doua Abdelrhaman, Waseem Hasan, Chadi Saad, Hamdi Mbarek, Borbala Mifsud, Sahar Isa Da'as   +10 more
wiley   +1 more source

The mitochondrial DNA copy number and ovary‐related reproductive disorders: A bidirectional two‐sample Mendelian randomization study

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 112-120, April 2025.
Abstract Objective In the present study, a bidirectional two‐sample Mendelian randomization approach was utilized to explore potential causal relationships between mitochondrial DNA copy number (mtDNA‐CN) and ovary‐related reproductive disorders (ORRDs), including ovarian dysfunction, ovarian cyst, polycystic ovary syndrome (PCOS), premature ovarian ...
Ke Peng, Xiao Han, Congquan Wu, Qiaowen Lu, Shujun Gao   +4 more
wiley   +1 more source

Inflammation in the endometrium of the tammar wallaby (Macropus eugenii) at the time of birth. [PDF]

Reprod Fertil
Muenzenberger MK, Menzies BR, Drews B.
europepmc   +1 more source

The effectiveness of a training program in improving the prenatal diagnosis accuracy of placenta accreta spectrum with ultrasound

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective This study evaluates the effectiveness of a structured training program in improving prenatal ultrasound diagnostic accuracy for placenta accreta spectrum (PAS) and assesses trainees' ability to recognize individual ultrasound markers of PAS.
Nicha Vetvitayavatana, Pharuhas Chanprapaph, Julaporn Pooliam   +2 more
wiley   +1 more source

Methodological Pitfalls in Endometriosis Biospecimen Research: Lessons From MAP4K4 Expression Studies. [PDF]

FASEB Bioadv
Badran D, Clarke H, Salvini S, Drury J, Tempest N, Maclean A, Hill CJ, Hapangama DK.   +7 more
europepmc   +1 more source

The effect of ovarian stimulation protocol on follicular asynchrony during in vitro fertilization – A retrospective cohort study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To examine the effect of controlled ovarian stimulation (COS) protocol on follicular synchrony in a subsequent in vitro fertilization (IVF) cycle in patients whose previous cycle was canceled due to asynchrony. Methods A single‐center retrospective‐cohort study (January 2018–March 2024), including women undergoing IVF who had: (1) a ...
Alyssa Hochberg, Maria Hincapie, Uri Amikam, Nir Kugelman, William Buckett, Shauna Reinblatt   +5 more
wiley   +1 more source

Reconstructing the Human Endometrium <i>In Vitro</i>: Current Three-Dimensional (3D) Models and Future Perspectives. [PDF]

Dev Reprod
Han SH, Cheon YP.
europepmc   +1 more source

Retrospective analysis of outcome after endometrial ablation with the NovaSure device: A German single‐center experience

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Evaluation of retrospective outcomes of NovaSure treatment in patients with abnormal uterine bleeding, including safety and cost‐effectiveness, and risk factors related to therapeutic outcomes. Subgroup analysis was conducted for patients who underwent concomitant surgical procedures, required subsequent interventions, and were ...
Oliver M. Schleicher, Felix Heindl, Julia Gocke, Katharina Keller, Lothar Häberle, Alaa Hamzeh, Christian Matek, Matthias W. Beckmann, Julius Emons   +8 more
wiley   +1 more source

Patient reported outcomes and results of endometrial balloon ablation for the treatment of heavy menstrual bleeding: A single center observational cohort study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Heavy menstrual bleeding is one of the most common gynecologic disorders among women of reproductive age and has a significant impact on their physical, psychological, and social well‐being. Although international guidelines recommend medical therapy as the first‐line treatment, it may prove ineffective, poorly tolerated, or ...
Jonas Rudaitis, Patricija Marozaite, Egle Bareikiene, Vilius Rudaitis   +3 more
wiley   +1 more source

Histopathological Changes in the Uterus, Ovaries, and Fallopian Tubes Following Testosterone Therapy in Transgender Men: A Retrospective Cohort Study from a Tertiary Referral Center. [PDF]

J Clin Med
Canbolat KH, Atılgan Yıldırım H, Urgancı N, İlvan Ş, Öncül M, Gök K, Tüten A.   +6 more
europepmc   +1 more source