Results 111 to 120 of about 201,910 (397)
The GGH/HuR Complex Binds and Stabilizes mRNAs to Maintain Tumor Cell Cycle and DNA Replication
Advanced Science, EarlyView.Despite its canonical role in inhibiting DNA synthesis, GGH promotes tumor growth as a novel RNA‐binding protein. GGH binds GC‐rich 5′UTRs (e.g., CDC6/CCND1), recruits HuR to form a ternary complex that stabilizes mRNA via circular conformation, fueling DNA replication and the cell cycle. Targeting this axis suppresses NSCLC progression.
Yu Li +9 more
wiley +1 more source
The relationship between endometrial thickness on the third day of cycle and the ovulation day
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2000 Objective: Infertility is a common health problem and its treatment is sometimes complicated by several factors. Endometrium thickness has been suggested as one of important predictor of uterine predisposition for pregnancy.
N Mousavi Far, N Mir Hoseini
doaj
The Egyptian Journal of Radiology and Nuclear Medicine, 2020 Background Previous studies reported changes in the local vasoactive substance production within the endometrium with a subsequent increase in vascularity as a possible mechanism of intrauterine contraceptive device (IUCD)-induced heavy menstrual ...
Mohamed S. Sweed +4 more
doaj +1 more source
Pulse of inflammatory proteins in the pregnant uterus of European polecats (Mustela putorius) leading to the time of implantation [PDF]
, 2017 Uterine secretory proteins protect the uterus and conceptuses against infection, facilitate implantation, control cellular damage resulting from implantation, and supply pre-implantation embryos with nutrients.
Burchmore, Richard J.S. +2 more
core +1 more source
Transcriptome sequencing of adenomyosis eutopic endometrium: A new insight into its pathophysiology
Journal of Cellular and Molecular Medicine, 2019 The eutopic endometrium has been suggested to play a crucial role in the pathogenesis of adenomyosis. However, the specific genes in eutopic endometrium responsible for the pathogenesis of adenomyosis still remain to be elucidated.
Yuqian Xiang +8 more
semanticscholar +1 more source
Advanced Science, EarlyView.Dysfunctional decidual CD4+T cells induce recurrent pregnancy loss via palmitoylation‐dependent Tim‐3 lysosomal sorting and degradation. The integrated bioinformatics, proteomic, functional and model studies elucidate that Tim‐3 is palmitoylated by ZDHHC3 at Cys9. Sortilin bound to and directed palmitoylated Tim‐3 toward lysosome degradation, resulting
Liyuan Cui +6 more
wiley +1 more source
Advanced Science, EarlyView.PAD1 is upregulated within the CD133+ subset or cisplatin‐resistant ovarian cancer cells, which is positively associated with the upregulation of stemness‐related markers and maintenance of stemness in OCSLCs. Mechanistically, PAD1‐catalyzed AKT2 citrullination at R202 facilitates AKT2 phosphorylation, promoting CEBPβ expression and its binding to the ...
Teng Xue +10 more
wiley +1 more source
THE PHYSIOLOGY OF THE ENDOMETRIUM AND UTERINE MUSCLE, AND OF THE OVARIAN CYCLE [PDF]
, 1937 J. M. Robson
openalex +3 more sources
Postpartum uterine diseases in dairy cows : a review with emphasis on subclinical endometritis [PDF]
, 2016 In this review, updated and precise definitions of the most common postpartum uterine diseases in dairy cows are provided. An aberrant uterine environment at inappropriate stages of the reproductive cycle inflicts damage to gametes and zygotes, impairing
Bogado Pascottini, Osvaldo Américo +1 more
core +1 more source
Advanced Science, EarlyView.Cardiovascular disease (CVD) and cancer are leading causes of death worldwide, with overlapping risk factors and pathophysiological mechanisms. This review explores shared pathways, including metabolic dysregulation, chronic inflammation, and gut microbiome alterations, highlighting dual‐benefit strategies such as lifestyle modifications and repurposed
Shihan Xiang +6 more
wiley +1 more source