Results 111 to 120 of about 143,576 (351)

Expression of steroid hormones receptors and morphofunctional condition endometrium at patients with anomalous uterine bleedings

Бюллетень сибирской медицины, 2009
The research of the influence of drug containing Indole-3-carbinol in combination with Kipferon on morphofunctional condition of endometrium with anomalous uterine bleedings is carried out.
I. P. Tayukina, L. M. Mustafina, O. A. Tikhonovskaya, S. V. Logvinov   +3 more
doaj   +1 more source

Lipid‐Driven OLR1/FOXM1/FGF19 Axis Orchestrates Crosstalk in an Epithelial‐Fibroblast Positive Feedback Promoting Progesterone Resistance in Endometrial Cancer

Advanced Science, EarlyView.
It is revealed that a metabolic–stromal loop driven by oxLDL–OLR1–FOXM1–FGF19 signaling promotes progesterone resistance in endometrial cancer. OxLDL activates epithelial–fibroblast crosstalk, enhancing proliferation and hormonal insensitivity. Disruption of this circuit, especially with resveratrol, restores MPA sensitivity, highlighting a potential ...
Xingchen Li, Yue Qi, Yuman Wu, Xinyi Bi, Yiqin Wang, Jiaqi Wang, Jingyuan Wang, Lingpu Zhang, Haihua Xiao, Jianliu Wang   +9 more
wiley   +1 more source

Autologous Intrauterine Platelet-Rich Plasma Instillation for Suboptimal Endometrium in Frozen Embryo Transfer Cycles: A Pilot Study

Journal of Human Reproductive Sciences, 2017
Introduction: This pilot study was to evaluate the effectiveness of intrauterine infusion of autologous platelet-rich plasma (PRP) in infertile women undergoing frozen embryo transfer cycles with suboptimal endometrium. Material and Methods: Intrauterine
S. Tandulwadkar, Manasi V. Naralkar, Akash D. Surana, M. Selvakarthick, A. Kharat   +4 more
semanticscholar   +1 more source

CypA Mediates Non‐Small Cell Lung Cancer Chemoresistance by Attenuating Ferroptosis via Stabilizing SLC7A11

Advanced Science, EarlyView.
Summary diagram for the role of CypA in chemoresistance in non‐small cell lung cancer (NSCLC). CypA is overexpressed in chemoresistance NSCLC and drives therapeutic evasion by competitively binding to the K37 site of SLC7A11, thereby blocking TRIM3 mediated K11‐linked ubiquitination and proteasomal degradation, ultimately inhibiting lipid peroxidation ...
Zhongcheng Wang, An Li, Ziwei Song, Xiangming Liu, Yong Ge, Zhiqiao Chen, Yuhui Liu, Boyu Zhang, Hao Zhang, Ting Lan   +9 more
wiley   +1 more source

Postmenopausal bleeding from a histological perspective

International Journal of Medicine and Health Development, 2000
Histopathoiogical findings in 170 Ibo women with postmenopausal bleeding were reviewed retrospectively over a 29 yesr period. In descending order, they were atrophic endometrium 21.7%,senile cystic endometrium 11.1%, squamous cell carcinoma of the cervix
H U Ezegwui, B C Ozumba, W I B. Onuigbo
doaj  

Targeting WEE1 in ARID1A/TP53 Concurrent Mutant Colorectal Cancer by Exploiting R‐Loop Accumulation and DNA Repair Deficiencies

Advanced Science, EarlyView.
ARID1A, a SWI/SNF complex component, is frequently mutated in colorectal cancer (CRC). CRC with ARID1A/TP53 concurrent mutations shows marked sensitivity to WEE1 inhibition. ARID1A loss induces R‐loop‐mediated replication stress, impairs ATF3 transcription, and amplifies WEE1i‐induced DNA damage, suggesting a promising therapeutic vulnerability ...
Chi Zhang, Yanjing Zhu, Luoyan Ai, Jingyuan Wang, Shan Yu, Yichen Wang, Xiaojing Xu, Mengling Liu, Yiyi Yu, Mengxuan Zhu, Yutong Liu, Zhenghang Xu, Haojie Zhou, Huishan Li, Qihong Huang, Qing Liu, Ke Peng, Tianshu Liu   +17 more
wiley   +1 more source

Endocrine Gland-Derived Vascular Endothelial Growth Factor Is Expressed in Human Peri-implantation Endometrium, But Not in Endometrial Carcinoma [PDF]

, 2005
Esw Ngan, K. Y. Lee, William S.B. Yeung, Hys Ngan, Ernest Hung Yu Ng, Patrick Ho   +5 more
openalex   +1 more source

Effects of Autologous Platelet-Rich Plasma on Regeneration of Damaged Endometrium in Female Rats

Yonsei medical journal, 2017
Purpose To investigate whether autologous platelet-rich plasma (PRP) treatment can improve regeneration of the endometrium in an experimental model of ethanol-induced damage.
Hang-Yong Jang, S. Myoung, Jeong Min Choe, Tak Kim, Y. Cheon, Yong Min Kim, Hyuntae Park   +6 more
semanticscholar   +1 more source

GSK3β‐Regulated Lipolysis is Required for Histone Acetylation and Decidualization in Early Pregnancy

Advanced Science, EarlyView.
Uterine Gsk3b knockout impairs decidual cell terminal differentiation by causing lipid droplet accumulation. GSK3β phosphorylates RNF213 to promote its lysosomal degradation, thereby enhancing lipolysis. The released fatty acids undergo β‐oxidation to generate acetyl‐CoA, which modulates histone acetylation and regulates decidual cell terminal ...
Peiran Wang, Yedong Tang, Xueling Zhao, Yu Ni, Hualan Zhou, Enhao Zhang, Gaizhen Li, Han Cai, Yinan Wang, James R. Woodgett, Wenbo Deng, Haibin Wang, Zhongxian Lu, Haili Bao, Shuangbo Kong   +14 more
wiley   +1 more source

Tamoxifen induction of angiogenic factor expression in endometrium [PDF]

, 2002
Stephen Hague, Sanjiv Manek, Martin K. Oehler, I.Z. MacKenzie, Roy Bicknell, Margaret Rees   +5 more
openalex   +1 more source