Estrogen Receptor Function: Impact on the Human Endometrium
The physiological role of estrogen in the female endometrium is well established. On the basis of responses to steroid hormones (progesterone, androgen, and estrogen), the endometrium is considered to have proliferative and secretory phases. Estrogen can
Kun Yu +5 more
doaj +2 more sources
Endometrium and endometriosis tissue mitochondrial energy metabolism in a nonhuman primate model
Background Endometriosis is the growth of uterine lining (endometrium) outside of the uterus. In other chronic inflammatory diseases, mitochondrial dysfunction is suspected of playing a role in disease pathogenesis.
Hannah M. Atkins +5 more
doaj +2 more sources
Amino acids in the uterine luminal fluid reflects the temporal changes in transporter expression in the endometrium and conceptus during early pregnancy in cattle [PDF]
In cattle, conceptus-maternal interactions are critical for the establishment and maintenance of pregnancy. A major component of this early interaction involves the transport of nutrients and secretion of key molecules by uterine epithelial cells to help
Bazer, Fuller W. +8 more
core +23 more sources
Mechanisms of Regeneration and Fibrosis in the Endometrium.
The uterine lining (endometrium) regenerates repeatedly over the life span as part of its normal physiology. Substantial portions of the endometrium are shed during childbirth (parturition) and, in some species, menstruation, but the tissue is rapidly ...
Claire J. Ang +2 more
semanticscholar +1 more source
Deciphering the endometrial niche of human thin endometrium at single-cell resolution
Significance Thin endometrium is the most common reason for uterine infertility and refractory gynecological diseases due to its complexity in pathogenesis and adverse pregnancy outcomes.
Haining Lv +11 more
semanticscholar +1 more source
Stem cell-based therapy for ameliorating intrauterine adhesion and endometrium injury
Intrauterine adhesion refers to endometrial repair disorders which are usually caused by uterine injury and may lead to a series of complications such as abnormal menstrual bleeding, recurrent abortion and secondary infertility.
Yu-Ting Song +6 more
semanticscholar +1 more source
Three-dimensional microengineered vascularised endometrium-on-a-chip
STUDY QUESTION Can we reconstitute physiologically relevant 3-dimensional (3D) microengineered endometrium in-vitro model? SUMMARY ANSWER Our representative microengineered vascularised endometrium on-a-chip closely recapitulates the endometrial ...
Jungho Ahn +10 more
semanticscholar +1 more source
Recurrent pregnancy loss is associated with a pro-senescent decidual response during the peri-implantation window [PDF]
During the implantation window, the endometrium becomes poised to transition to a pregnant state, a process driven by differentiation of stromal cells into decidual cells (DC).
Brighton, Paul (Paul J.) +12 more
core +1 more source
Cancer of the endometrium [PDF]
1Centre Leon Berard, Lyon; 2FNCLCC, Paris; 3Institut Bergonie, Bordeaux; 4Centre Jean Perrin, Clermont-Ferrand; 5Centre Paul Papin, Angers; 6CHU Bretonneau, Tours; 7Centre Alexis Vautrin, Nancy; 8Centre Henri Becquerel, Rouen; 9CHU, Angers; 10CHU, Hopital Arnaud de Villeneuve, Montpellier; 11Centre Paul Strauss, Strasbourg; 12Clinique Sainte-Catherine,
Jean-Paul Guastalla +17 more
openaire +3 more sources
Background: Methylenetetrahydrofolate reductase enzyme (MTHFR) plays a key role in regulating folate balance, converting homocysteine to methionine, and producing s-adenosylmethionine (SAM) that plays a role in the methylation process.
Khadijeh Baranizadeh +6 more
doaj +1 more source

