Results 11 to 20 of about 159,563 (339)

Impact of sitagliptin on endometrial mesenchymal stem-like progenitor cells : a randomised, double-blind placebo-controlled feasibility trial [PDF]

, 2020
Background: Recurrent pregnancy loss (RPL) is associated with the loss of endometrial mesenchymal stem-like progenitor cells (eMSC). DPP4 inhibitors may increase homing and engraftment of bone marrow-derived cells to sites of tissue injury.
Brighton, Paul (Paul J.), Brosens, Jan J., Da Costa, Maria José Minhoto Diniz, Ewington, Lauren J., Fishwick, Katherine, Fujihara, Risa, Kimani, Peter K., Lacey, Lauren, Lucas, Emma S., Muter, Joanne, Polanco, Angela, Quenby, Siobhan, Takeda, Satoru, Tewary, Shreeya   +13 more
core   +1 more source

Evaluation of methylenetetrahydrofolate reductase and S-adenosyl-methionine level in male infertility: A case-control study

International Journal of Reproductive BioMedicine, 2022
Background: Methylenetetrahydrofolate reductase enzyme (MTHFR) plays a key role in regulating folate balance, converting homocysteine to methionine, and producing s-adenosylmethionine (SAM) that plays a role in the methylation process.
Khadijeh Baranizadeh, Maryam Bahmanzadeh, Heidar Tavilani, Tayebeh Ghiasvand, Iraj Amiri, Mahnaz Yavangi, Gholamreza Shafiee   +6 more
doaj   +1 more source

Progestins Related to Progesterone and Testosterone Elicit Divergent Human Endometrial Transcriptomes and Biofunctions. [PDF]

, 2020
Progestins are widely used for the treatment of gynecologic disorders and alone, or combined with an estrogen, are used as contraceptives. While their potencies, efficacies and side effects vary due to differences in structures, doses and routes of ...
Balayan, Shayna, Chen, Joseph C, Giudice, Linda C, Greenblatt, Ruth M, Houshdaran, Sahar, Irwin, Juan C, Smith-McCune, Karen, Vallvé-Juanico, Júlia, Vo, Kim Chi   +8 more
core   +2 more sources

Immunohistochemical expression of Drosha is reduced in eutopic and ectopic endometrium of women with adenomyosis

Brazilian Journal of Medical and Biological Research, 2022
The objective of this study was to evaluate the immunohistochemical expression of Dicer, Drosha, and Exportin-5 in the eutopic and ectopic endometrium of women with adenomyosis.
I. Ormenezi, A. Ribeiro-Silva, J.C. Rosa-e-Silva, J. Meola, F.J. Candido-dos-Reis, O.B. Poli-Neto   +5 more
doaj   +1 more source

A pilot and ex-vivo study of examination of endometrium tissue by catheter based optical coherence tomography

BMC Medical Imaging, 2022
Objective This study aimed to distinguish ex-vivo normal and abnormal endometrium tissue samples histologically by catheter based optical coherence tomography (OCT).
Bo Ding, Tao Jinyuan, Kuiyuan Tao, Zhenyang Ding, Shen Yang   +4 more
doaj   +1 more source

Fibroblast growth factor 1 ameliorates thin endometrium in rats through activation of the autophagic pathway

Frontiers in Pharmacology, 2023
Background: Thin endometrium is a reproductive disorder that affects embryo implantation. There are several therapies available for this disease, however they are not so effective. Fibroblast growth factor 1 (FGF1) is a member of fibroblast growth factor
Jing Zhu, Zhenyao Li, Fengli Yin, Xiaoting Yu, Yuanfan Lu, Tong Zhou, Fanghua Gong, Zhangye Xu   +7 more
doaj   +1 more source

Effects of Testicular Platelet-Rich Plasma (PRP) Injection on Sperm Parameters in Men with Severe Oligoasthenoteratozoospermia (OAT): A Clinical Evaluation [PDF]

International Journal of Fertility and Sterility
Background: Severe oligoasthenoteratozoospermia (OAT), characterized by a reduced sperm count, motility, andaltered morphology, presents a significant challenge in the field of male infertility.
Faezeh Fazli, Hossein Torkashvand, Ali Reza Soltanian, Ali Babalhavaeji, Hanieh Olomi, Shamim Pilehvari   +5 more
doaj   +1 more source

Total tissue lactate dehydrogenase activity in endometrial carcinoma [PDF]

, 2008
Lactate dehydrogenase (LDH) is essential for continuous glycolysis necessary for accelerated tumor growth. The aim of this study was to reconsider if assay of total tissue activity of this enzyme could be useful as marker for endometrial carcinoma (EC ...
Abramić, Marija, Babić, Damir, Ilić-Forko, Jadranka, Osmak, Maja, Šimaga, Šumski   +4 more
core   +1 more source

Recurrent pregnancy loss is associated with a pro-senescent decidual response during the peri-implantation window [PDF]

, 2020
During the implantation window, the endometrium becomes poised to transition to a pregnant state, a process driven by differentiation of stromal cells into decidual cells (DC).
Brighton, Paul (Paul J.), Brosens, Jan J., Diniz-da-Costa, Maria, Ewington, Lauren J., Fishwick, Katherine J., Kong, Chow-Seng, Lipecki, Julia, Lucas, Emma S., Muter, Joanne, Odendaal, Joshua, Ott, Sascha, Quenby, Siobhan, Vrljicak, Pavle   +12 more
core   +1 more source

Human Umbilical Cord Mesenchymal Stem Cells Encapsulated with Pluronic F-127 Enhance the Regeneration and Angiogenesis of Thin Endometrium in Rat via Local IL-1β Stimulation

Stem Cells International, 2022
Thin endometrium (< 7 mm) could cause low clinical pregnancy, reduced live birth, increased spontaneous abortion, and decreased birth weight. However, the treatments for thin endometrium have not been well developed.
Shuling Zhou, Yu Lei, Ping Wang, Jianying Chen, Liting Zeng, Ting Qu, Martin Maldonado, Jihua Huang, Tingting Han, Zina Wen, Erpo Tian, Xiangqian Meng, Ying Zhong, Jiang Gu   +13 more
doaj   +1 more source