Results 211 to 220 of about 201,910 (397)

Integrative omics approaches to uncover liquid‐based cancer‐predicting biomarkers in Lynch syndrome

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Lynch syndrome (LS) significantly increases lifetime cancer risk, necessitating innovative approaches for risk stratification. Current risk assessment methods, however, fail to integrate data from different biological systems, which may be influenced by lifestyle factors.
Minta Kärkkäinen   +9 more
wiley   +1 more source

The mitochondrial DNA copy number and ovary‐related reproductive disorders: A bidirectional two‐sample Mendelian randomization study

open access: yesInternational Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 112-120, April 2025.
Abstract Objective In the present study, a bidirectional two‐sample Mendelian randomization approach was utilized to explore potential causal relationships between mitochondrial DNA copy number (mtDNA‐CN) and ovary‐related reproductive disorders (ORRDs), including ovarian dysfunction, ovarian cyst, polycystic ovary syndrome (PCOS), premature ovarian ...
Ke Peng   +4 more
wiley   +1 more source

A systems-based approach to uterine fibroids identifies differential splicing associated with abnormal uterine bleeding. [PDF]

open access: yesCommun Med (Lond)
Wang CY   +23 more
europepmc   +1 more source

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