Frontiers in Pharmacology, 2023 Background: Thin endometrium is a reproductive disorder that affects embryo implantation. There are several therapies available for this disease, however they are not so effective. Fibroblast growth factor 1 (FGF1) is a member of fibroblast growth factor
Jing Zhu +7 more
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Autophagy in the physiological endometrium and cancer
Autophagy, 2020 Autophagy is a highly conserved catabolic process and a major cellular pathway for the degradation of long-lived proteins and cytoplasmic organelles. An increasing body of evidence has unveiled autophagy as an indispensable biological function that helps
Laura Devis-Jauregui +4 more
semanticscholar +1 more source
Impact of sitagliptin on endometrial mesenchymal stem-like progenitor cells : a randomised, double-blind placebo-controlled feasibility trial [PDF]
, 2020 Background: Recurrent pregnancy loss (RPL) is associated with the loss of endometrial mesenchymal stem-like progenitor cells (eMSC). DPP4 inhibitors may increase homing and engraftment of bone marrow-derived cells to sites of tissue injury.
Brighton, Paul (Paul J.) +13 more
core +1 more source
Effects of Testicular Platelet-Rich Plasma (PRP) Injection on Sperm Parameters in Men with Severe Oligoasthenoteratozoospermia (OAT): A Clinical Evaluation [PDF]
International Journal of Fertility and SterilityBackground: Severe oligoasthenoteratozoospermia (OAT), characterized by a reduced sperm count, motility, andaltered morphology, presents a significant challenge in the field of male infertility.
Faezeh Fazli +5 more
doaj +1 more source
Histone acetylation and the role of histone deacetylases in normal cyclic endometrium
Reproductive Biology and Endocrinology, 2020 Histone acetylation is a critical epigenetic modification that changes chromatin architecture and regulates gene expression by opening or closing the chromatin structure. It plays an essential role in cell cycle progression and differentiation. The human
Palak Gujral +3 more
semanticscholar +1 more source
Stem Cells International, 2022 Thin endometrium (< 7 mm) could cause low clinical pregnancy, reduced live birth, increased spontaneous abortion, and decreased birth weight. However, the treatments for thin endometrium have not been well developed.
Shuling Zhou +13 more
doaj +1 more source
Comparison of the Effects of Early Pregnancy with Human Interferon, Alpha 2 (IFNA2), on Gene Expression in Bovine Endometrium [PDF]
, 2012 Interferon tau (IFNT), a type I IFN similar to alpha IFNs (IFNA), is the pregnancy recognition signal produced by the ruminant conceptus. To elucidate specific effects of bovine IFNT and of other conceptus-derived factors, endometrial gene expression ...
Bauersachs, Stefan +10 more
core +1 more source
Reproduction and Fertility, 2023 Genome-wide analysis of gene expression has been widely applied to study the endometrium, although to our knowledge no systematic reviews have been performed.
Evangeline R Walker +4 more
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Long-term, hormone-responsive organoid cultures of human endometrium in a chemically-defined medium
Nature Cell Biology, 2017 In humans, the endometrium, the uterine mucosal lining, undergoes dynamic changes throughout the menstrual cycle and pregnancy. Despite the importance of the endometrium as the site of implantation and nutritional support for the conceptus, there are no ...
M. Turco +14 more
semanticscholar +1 more source
Receptivity at different endometrial thickness in women of reproductive age (literature review) [PDF]
Гинекология, 2022 Overcoming infertility and reducing miscarriage are important challenges in obstetrics and gynecology. In the Russian Federation, the frequency of infertile couples reaches 24%; the percentage of miscarriage does not decrease, accounting for up to 20% of
Sergey S. Aganezov +2 more
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