Results 71 to 80 of about 94,099 (313)

The Role of Combined Treatment of Granulocyte Colony-stimulating Factor and Oestrogen in Treatment of Thin Endometrium: A Rat Model

Journal of Human Reproductive Sciences
Background: Thin endometrium, described as endometrial thickness below 7 mm on embryo transfer day in assisted reproduction cycles, is associated with decreased pregnancy rates.
Inci Kahyaoglu, Gülnur Take Kaplanoglu, Gökçe Nur Arik Erol, Serkan Kahyaoglu   +3 more
doaj   +1 more source

Dose‐Dependent Reprogramming of Chromatin Accessibility by SOX4 Drives the Transcriptional Response to Iron Overload

Advanced Science, EarlyView.
This study demonstrates that iron overload triggers widespread chromatin compaction and transcriptional repression in human granulosa cells, recapitulating features of endometriosis. The epigenetic reprogramming is orchestrated by a TFEB‐SOX4‐SWI/SNF axis, with SOX4 acting as a central, dosage‐sensitive regulator.
Feifei Li, Yaoqiu Wu, Guangyu Yang, Jingyi Lai, Xiaoyue Sun, Liyan Wang, Xiaoli Li, Jing Zhang, Qingxue Zhang, Hui Chen, Haiyan Lin, Bingxiang Xu, Junfeng Zhang, Hailong Wang, Anming Meng, Chunwei Cao   +15 more
wiley   +1 more source

Augmented cell survival in eutopic endometrium from women with endometriosis: Expression of c-myc, TGF-beta1 and bax genes

Reproductive Biology and Endocrinology, 2005
Background Endometriosis is a common gynaecological disorder characterized by the presence of endometrial tissue outside of the uterus. The fragments in normal menstruation are composed of necrotic and living cells, which do not survive in ectopic ...
Vega Margarita, Fuentes Ariel, Bacallao Ketty, Alves Alessandra, Torres Marisa, Johnson M Cecilia, Boric M Angélica   +6 more
doaj   +1 more source

Reassessing the Proposed Creatine–PrP Axis in Endometriosis: Methodological and Mechanistic Considerations

Advanced Science, EarlyView.
ABSTRACT The research by Chen et al. (2024) presents an innovative hypothesis linking creatine metabolism to ferroptosis resistance in endometriotic stromal cells via PrP suppression. While conceptually valuable, methodological aspects warrant reflection.
Marco Machado
wiley   +1 more source

Correlation between aromatase expression in the eutopic endometrium of symptomatic patients and the presence of endometriosis [PDF]

, 2012
Hugo Maia Jr1,2, Clarice Haddad1,2, Julio Casoy11CEPARH, 2Itaigara Memorial Day Hospital, Salvador, Bahia, BrazilObjective: To investigate whether aromatase expression in the eutopic endometrium correlates with the presence and severity of endometriosis ...
Maia Jr H, Casoy J, Haddad C
core  

Effects of selective oestrogen receptor modulators on proliferation in tissue cultures of pre- and postmenopausal human endometrium [PDF]

, 2008
We characterised the effects of selective oestrogen receptor modulators (SERM) in explant cultures of human endometrium tissue. Endometrium tissues were cultured for 24 h in Millicell-CM culture inserts in serum-free medium in the presence of vehicle,17 ...
Ederveen, A., Punyadeera, Chamindie, Kamps, R., Groothuis, P, Dijcks, F, Defrere, Sylvie, Punyadeera, C., Groothuis, P., Punyadeera, C, Kamps, R, Dunselman, G, de Goeij, A., Dunselman, G., de Goeij, A, Dijcks, F., Defrere, S, Ederveen, A, Defrere, S.   +17 more
core   +1 more source

Comparison of T and NK lymphocyte subsets between human endometrial tissue and peripheral blood

Central European Journal of Immunology, 2019
Immune profiles in endometrium may be changed in patients with IVF failure and its possible correlations with immune parameters in peripheral blood are important for the diagnostic approach.
Viktor Chernyshov, Boris Dons’koi, Iryna Sudoma, Yana Goncharova   +3 more
doaj   +1 more source

Unveiling Lactylation: A Novel Frontier in Cancer Stemness and Therapy

Advanced Science, EarlyView.
Tumor metabolism and epigenetic regulation are intrinsically linked. This review highlights lactylation as a pivotal bridge connecting these processes, acting as an active epigenetic effector in cancer stemness. We delineate how lactylation orchestrates the cancer stem cell landscape and evaluate its regulatory networks.
Ting Li, Hongyu Gu, Chang Liu, Yuesheng Lv, Feifei Li, Liang Liang, Jia Yi, Xuanyi Wang, Yi Zhun Zhu, Chuan Xu   +9 more
wiley   +1 more source

Efficacy of silicone sheet as a personalized barrier for preventing adhesion reformation after hysteroscopic adhesiolysis of intrauterine adhesions

Reproductive Medicine and Biology, 2019
Purpose To evaluate the efficacy of silicone sheet as a new type of barrier for preventing adhesion reformation following hysteroscopic adhesiolysis of intrauterine adhesions (IUAs).
Atsushi Azumaguchi, Hirofumi Henmi, Tsuyoshi Saito   +2 more
doaj   +1 more source

Apoptosis is increased and cell proliferation is decreased in out-of-phase endometria from infertile and recurrent abortion patients

Reproductive Biology and Endocrinology, 2010
Background Various endometrial abnormalities have been associated with luteal phase deficiency: a significant dyssynchrony in the maturation of the glandular epithelium and the stroma and a prevalence of out-of-phase endometrial biopsy specimens.
Irigoyen Marcela, Alfie Margarita, Vighi Susana, Olivares Carla, Meresman Gabriela F, Etchepareborda Juan J   +5 more
doaj   +1 more source