Results 71 to 80 of about 160,423 (342)
Advanced Science, EarlyView.CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He +17 more
wiley +1 more source
Comparison of T and NK lymphocyte subsets between human endometrial tissue and peripheral blood
Central European Journal of Immunology, 2019 Immune profiles in endometrium may be changed in patients with IVF failure and its possible correlations with immune parameters in peripheral blood are important for the diagnostic approach.
Viktor Chernyshov +3 more
doaj +1 more source
The effects of androgen therapy on the endometrium of transgender men [PDF]
, 2017 Individuals who identify themselves as transgender have gender identities that do not match their anatomical sex. Females who identify as male, also known as female-to-male transgender (FTM), may opt to undergo hormonal and surgical treatment in order to
Shah, Anita
core
Mutations and amplification of oncogenes in endometrial cancer [PDF]
, 1999 Alterations in oncogenes are critical steps in the development of endometrial cancer. To investigate the potential clinical relevance of the amplification of the oncogenes c-erbB2, c-myc, and int-2 and the mutation of K-ras in endometrial cancer, 112 ...
An, Han-Xiang +5 more
core +1 more source
Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy
Advanced Science, EarlyView.Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong +5 more
wiley +1 more source
Middle East Fertility Society Journal, 2015 Objective: To study the histopathology of endometrium and the serum concentration of sex steroid hormones in different types of atrophic endometrium associated with postmenopausal uterine bleeding (PMB). Design: Prospective observational study.
Dina Gamal Eldeen Elkholi +1 more
doaj +1 more source
Xanthogranulomatous endometritis [PDF]
, 1989 Xanthogranulomatous inflammatory changes of the endometrium are rare and appear to be related to obstructive changes in the endocervical canal. An elderly patient with an advanced squamous carcinoma of the cervix uteri presented with this condition ...
Busuttil, Anthony, Soria, M.
core
Uterine selection of human embryos at implantation [PDF]
, 2014 Human embryos frequently harbor large-scale complex chromosomal errors that impede normal development. Affected embryos may fail to implant although many first breach the endometrial epithelium and embed in the decidualizing stroma before being rejected ...
A Mertzanidou +44 more
core +2 more sources
Sphingomonas paucimobilis‐Driven Epithelial–Endothelial Transition in Adenomyosis Pathogenesis
Advanced Science, EarlyView.This study identifies epithelial–endothelial transition (EET) as a novel adenomyosis pathogenic mechanism driven by Sphingomonas paucimobilis colonization. Systematic inhibitor experiments validate a TNFα→NF‐κB→MMP signaling cascade essential for EET. Critically, bacterial culture supernatant fails to induce pathological changes, demonstrating viable ...
Peigen Chen +7 more
wiley +1 more source
Collagen and Eosinophils in Jenny's Endometrium: Do They Differ With Endometrial Classification?
Frontiers in Veterinary Science, 2020 Collagen fibers and inflammatory cells are the basis for jenny endometrium Kenney and Doig's classification developed for the mare. The infiltration of a large number of eosinophils in the jenny endometrium is intriguing.
Jordi Miró +8 more
doaj +1 more source