Results 71 to 80 of about 77,089 (218)

Postmenopausal bleeding from a histological perspective

open access: yesInternational Journal of Medicine and Health Development, 2000
Histopathoiogical findings in 170 Ibo women with postmenopausal bleeding were reviewed retrospectively over a 29 yesr period. In descending order, they were atrophic endometrium 21.7%,senile cystic endometrium 11.1%, squamous cell carcinoma of the cervix
H U Ezegwui, B C Ozumba, W I B. Onuigbo
doaj  

CausalCellInfer: Prioritizing Cell‐Type‐Specific Disease Associations From Genetically Predicted Transcriptomes in Biobank Cohorts

open access: yesAdvanced Science, EarlyView.
Bulk and genotype‐imputed transcriptomes obscure the cellular drivers of complex disease. CausalCellInfer resolves them by integrating invariant marker selection, deep learning deconvolution, and regularized matrix completion. Applied to ∼500 000 UK Biobank participants across 29 traits, it uncovers hallmark cell‐type proportion shifts, including ...
Liangying Yin   +6 more
wiley   +1 more source

The Characteristics of Tumor Microenvironment by the Single Cell Profile in Endometrial Cancer of no Specific Molecular Profile (NSMP) Subtype

open access: yesAdvanced Science, EarlyView.
A subset of tumor‐associated macrophages (TAMs) characterized by SPP1 expression is discovered, which may remodel the tumor microenvironment by potentially promoting CD4+ T cell stress and maintaining epithelial cell stemness through SPP1‐CD44, thereby potentially contributing to the proliferation and migration of tumor cells, which has been verified ...
Xinhui Yuan   +5 more
wiley   +1 more source

Morphological features and activity of estrogen receptors of endometrium and foci of adenomyosis in postmenopausal patients

open access: yesPatologìâ, 2016
Aim. The article is devoted to the research of morphological features and activity of estrogen receptors of endometrium and foci of adenomyosis in postmenopausal patients. Materials and methods. 30 cases of adenomyosis were investigated in the presence
V. A. Sitnikova   +2 more
doaj   +1 more source

AI‐Driven Cancer Multi‐Omics: A Review From the Data Pipeline Perspective

open access: yesAdvanced Intelligent Discovery, EarlyView.
The exponential growth of cancer multi‐omics data brings opportunities and challenges for precision oncology. This review systematically examines AI's role in addressing these challenges, covering generative models, integration architectures, Explainable AI for clinical trust, clinical applications, and key directions for clinical translation.
Shilong Liu, Shunxiang Li, Kun Qian
wiley   +1 more source

KORELASI EKSPRESI IMMUNOSITOKIMIA VASCULAR ENDOTHELIAL GROWTH FACTOR A (VEGF A) DENGAN PROTEIN GENE PRODUCT 9,5 (PGP 9,5) DARAH HAID PADA PATOFISIOLOGI ENDOMETRIOSIS

open access: yesAndalas Obstetrics and Gynecology Journal, 2017
Terdapat perubahan fenotip molekuler endometrium eutopik pada endometriosis berupa perubahan ekspresi gen, respon terhadap hormone steroid, peningkatan marker inflamasi dan molekul adesi seluler, penurunan indeks apoptosis dan kapasitas desidualisasi ...
Dedy Hendry   +3 more
doaj   +1 more source

Clinically Informed Intelligent Classification of Ovarian Cancer Cells by Label‐Free Holographic Imaging Flow Cytometry

open access: yesAdvanced Intelligent Systems, Volume 7, Issue 3, March 2025.
Quantitative phase maps of single cells recorded in flow cytometry modality feed a hierarchical architecture of machine learning models for the label‐free identification of subtypes of ovarian cancer. The employment of a priori clinical information improves the classification performance, thus emulating the clinical application of liquid biopsy during ...
Daniele Pirone   +11 more
wiley   +1 more source

Community partner perspectives on community‐academic health research partnerships with Black American communities: A scoping review

open access: yesAmerican Journal of Community Psychology, EarlyView.
Abstract Evaluations of community‐engaged research (CEnR) typically emphasize health outcomes rather than the partnership processes that contribute to intervention effectiveness. This scoping review synthesized community partner‐identified strategies for successful community‐academic health research partnerships with Black American communities and ...
Kaylyn A. Garcia   +6 more
wiley   +1 more source

Biomimetic Nanofiber Scaffold Coated With Acellular Matrices for Uterine Myometrial Tissue Engineering

open access: yesAdvanced NanoBiomed Research, EarlyView.
Schematic representation of acellular matrix generation from human uterine fibroblast cells, coating on polycaprolactone electrospun nanofibers, and subsequent in vitro and in vivo characterization. A tissue‐engineered scaffold tailored for uterine myometrium‐specific regeneration is designed. The electrospinning technique was used to fabricate aligned
Srividya Hanuman   +3 more
wiley   +1 more source

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