Results 111 to 120 of about 271,229 (377)

Electrochemical‐Genetic Programming of Protein‐Based Magnetic Soft Robots for Active Drug Delivery

Advanced Science, EarlyView.
This manuscript presents a protein‐based soft robot for active drug delivery. Stimuli‐responsive protein is rationally designed and processed into the substrate of robots. Superparamagnetic Fe3O4 nanoparticles are patterned on the substrate using an electrochemical method, enabling the robot to respond to external physical fields.
Hang Zhao, Bo Yu, Dingyi Yu, Ting Ji, Kexin Nie, Jingyi Tian, Xinchen Shen, Kaiyue Zhang, Junhan Ou, Xinyi Yang, Dongfang Xiao, Qi Zhou, Wenwen Huang   +12 more
wiley   +1 more source

Development of FRET-based cap-snatching endonuclease assay

Microbiology Spectrum
The order Bunyavirales consists of over 300 species of segmented, negative-strand RNA viruses. These viruses have a tri-segmented genome (S, M, and L segments) that encodes the nucleocapsid protein (N protein), glycoprotein precursor, and RNA-dependent ...
Jeeva Subbiah, Austin Royster, Sheema Mir, Mohammad Mir   +3 more
doaj   +1 more source

Mlh1-Mlh3, a Meiotic Crossover and DNA Mismatch Repair Factor, Is a Msh2-Msh3-stimulated Endonuclease*

Journal of Biological Chemistry, 2014
Background: Meiotic crossing over requires resolution of Holliday junctions through actions of the DNA mismatch repair factor Mlh1-Mlh3. Results: Mlh1-Mlh3 is a metal-dependent, Msh2-Msh3-stimulated endonuclease.
M. Rogacheva, Carol M. Manhart, Cheng Chen, A. Guarné, J. Surtees, E. Alani   +5 more
semanticscholar   +1 more source

Splicing Endonuclease Is an Important Player in rRNA and tRNA Maturation in Archaea

Frontiers in Microbiology, 2020
In all three domains of life, tRNA genes contain introns that must be removed to yield functional tRNA. In archaea and eukarya, the first step of this process is catalyzed by a splicing endonuclease.
Thandi S. Schwarz, Sarah J. Berkemer, Sarah J. Berkemer, Sarah J. Berkemer, Stephan H. Bernhart, Stephan H. Bernhart, Matthias Weiß, Sébastien Ferreira-Cerca, Peter F. Stadler, Peter F. Stadler, Peter F. Stadler, Peter F. Stadler, Peter F. Stadler, Peter F. Stadler, Peter F. Stadler, Peter F. Stadler, Peter F. Stadler, Anita Marchfelder   +17 more
doaj   +1 more source

Using electrostatic potentials to predict DNA-binding sites on DNA-binding proteins [PDF]

, 2003
A method to detect DNA-binding sites on the surface of a protein structure is important for functional annotation. This work describes the analysis of residue patches on the surface of DNA-binding proteins and the development of a method of predicting ...
Berman, Helen M, Jones, Susan, Shanahan, Hugh P, Thornton, Janet M   +3 more
core   +4 more sources

Engineered Hydrogels Revolutionize Locoregional Cancer Immunotherapy

Advanced NanoBiomed Research, EarlyView.
This review systematically summarizes the latest research progress on injectable hydrogels in cancer immunotherapy, highlighting their unique advantages in precise immune activation, local drug‐controlled release, and immune microenvironment remodeling. These features provide innovative solutions to overcome the bottlenecks of systemic side effects and
Jiyong Wei, Chunliu Huang, Zenghua Zhou, Yanni Lan   +3 more
wiley   +1 more source

Mitochondrial Haplotype-based Identification of Root-knot Nematodes (Meloidogyne spp.) on Cut Foliage Crops in Florida [PDF]

Journal of Nematology, 2016
RICHARD BAIDOO, SOUMI JOSEPH, TESFAMARIAM M. MENGISTU, JANETE A. BRITO, ROBERT MCSORLEY, ROBERT H. STAMPS, WILLIAM T. CROW   +6 more
doaj   +1 more source

Single Strand Annealing and ATP-independent Strand Exchange Activities of Yeast and Human DNA2: possible role in Ozaki fragment maturation [PDF]

, 2006
The Dna2 protein is a multifunctional enzyme with 5'-3' DNA helicase, DNA-dependent ATPase, 3' exo/endonuclease, and 5' exo/endonuclease. The enzyme is highly specific for structures containing single-stranded flaps adjacent to duplex regions.
Campbell, Judith L., Masuda-Sasa, Taro, Polaczek, Piotr   +2 more
core  

The subnuclear localization of tRNA ligase in yeast [PDF]

, 1987
Yeast tRNA ligase is an enzyme required for tRNA splicing. A study by indirect immune fluorescence shows that this enzyme is localized in the cell nucleus. At higher resolution, studies using indirect immune electron microscopy show this nuclear location
Abelson, John, Clark, Michael W.
core   +1 more source

Characterization of ExeM, an Extracellular Nuclease of Shewanella oneidensis MR-1

Frontiers in Microbiology, 2018
Bacterial extracellular nucleases have multiple functions in processes as diverse as nutrient acquisition, natural transformation, biofilm formation, or defense against neutrophil extracellular traps (NETs).
Lucas Binnenkade, Maximilian Kreienbaum, Kai M. Thormann   +2 more
doaj   +1 more source