Results 181 to 190 of about 271,229 (377)

Rapid and Sensitive Detection of RNA Viruses through Imaging of Marker Molecules Derived from Designed Circular DNA Probes

open access: yesSmall Methods, EarlyView.
This study presents a rapid and sensitive virus detection method that employs imaging of virus‐specific DNA markers. Utilizing specially designed single‐stranded circular DNA probes, this method captures RNA fragments from RNase‐digested viral genomes during the reverse transcriptase‐based reaction, resulting in double‐stranded markers that are ...
Yoon‐ha Jang   +13 more
wiley   +1 more source

The Specificity of Escherichia coli Endonuclease I [PDF]

open access: bronze, 1973
S. Dusko Ehrlich   +2 more
openalex   +1 more source

CRISPR/Cas9‐edited tumor‐associated immune cells in cancer immunotherapy

open access: yesVIEW, EarlyView.
Abstract Immuno‐oncology represents an emerging field that has significantly transformed tumor therapeutics, with immune cells serving as the cellular foundations of cancer immunotherapy. Due to its high efficiency and sensitivity, CRISPR/Cas9 genome editing is a highly promising technique for precise and rapid gene modification.
Yuhui Ma   +6 more
wiley   +1 more source

Cleavage of Adenovirus Type 2 DNA into Six Unique Fragments by Endonuclease R·RI [PDF]

open access: green, 1973
Ulf Pettersson   +3 more
openalex   +1 more source

Mechanistic Insights Into 5′‐tiRNA‐His‐GTG Mediated Activation of the JNK Pathway in Skin Photoaging

open access: yesAging Cell, EarlyView.
5′‐tiRNA‐His‐GTG expression level is upregulated in the photoaging cell model. 5′‐tiRNA‐His‐GTG negatively regulates the expression of NUP98, thereby activating the JNK signaling pathway to regulate cell senescence. ABSTRACT UV exposure leads to skin damage, thus inducing skin aging.
Lihao Liu   +10 more
wiley   +1 more source

Dietary Restriction Mitigates Vascular Aging, Modulates the cGAS‐STING Pathway and Reverses Macrophage‐Like VSMC Phenotypes in Progeroid DNA‐Repair‐Deficient Ercc1Δ/− Mice

open access: yesAging Cell, EarlyView.
Dietary restriction mitigates vascular aging in DNA‐repair‐deficient Ercc1Δ/− mice by reducing extracellular matrix remodeling, inflammation, oxidative stress, and switching of vascular smooth muscle cells to a macrophage‐like phenotype. Our findings suggest that the cGAS‐STING pathway plays a key role in vascular aging and that the benefits of dietary
S. J. M. Stefens   +14 more
wiley   +1 more source

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