Results 301 to 310 of about 271,229 (377)

An Update: Enzymatic Synthesis for Industrial Applications

Angewandte Chemie International Edition, Volume 64, Issue 27, July 1, 2025.
Biocatalysis has become a sustainable and cost‐competitive alternative to established chemical synthesis, enabling the enzyme‐based production of not only commodity chemicals but (non‐natural) amino acids, (rare) sugars, as well as synthetic nucleotides.
Thomas Bayer, Shuke Wu, Radka Snajdrova, Kai Baldenius, Uwe T. Bornscheuer   +4 more
wiley   +1 more source

In Vitro Structure-Activity Relationship Stability Study of Antisense Oligonucleotide Therapeutics Using Biological Matrices and Nucleases. [PDF]

Pharmacol Res Perspect
Lovrić J, Yan J, Li X, Karlsborn T, Bood M, Dahlén A, Hilgendorf C, Bhatt DK.   +7 more
europepmc   +1 more source

Isolation, Chemical Structure, and Antagonistic Activity Against Galectin‐1 of Water‐Soluble Polysaccharides From Plantago asiatica

Food Science &Nutrition, Volume 13, Issue 7, July 2025.
Plantago asiatica has been utilized as a dietary supplement in health foods and for medicinal purposes, enjoying a long‐standing acceptance throughout history. This study will provide new insights into the relationship between the antagonistic activity against galectin‐1 of P.asiatica polysaccharides and their applications in the fields of food and ...
Yiqing Li, Yonghong Ma, Guanyu Li, Yanqing Jia, Chengxin Sun, Liushaoqiu Zhou, Wenqin Lei, Tao Zhang   +7 more
wiley   +1 more source

Structural characterization of the full-length Hantaan virus polymerase. [PDF]

PLoS Pathog
Keown JR, Carrique L, Nilsson-Payant BE, Fodor E, Grimes JM.   +4 more
europepmc   +1 more source

Mitochondria‐Associated Endoplasmic Reticulum Membranes in Human Health and Diseases

MedComm, Volume 6, Issue 7, July 2025.
MAM dysfunction is considered as an initiator or contributor in the progression of various diseases such as nervous system diseases, circulatory system diseases, digestive system diseases, locomotor system diseases, reproductive system diseases, endocrine system diseases, urinary system diseases, respiratory system diseases and cancer.
Yong Liu, Zi‐Hui Mao, Junwen Huang, Hui Wang, Xiao Zhang, Xin Zhou, Yue Xu, Shaokang Pan, Dongwei Liu, Zhangsuo Liu, Qi Feng   +10 more
wiley   +1 more source

Repair pathway coordination from gap filling by polβ and subsequent nick sealing by LIG1 or LIG3α governs BER efficiency at the downstream steps. [PDF]

DNA Repair (Amst)
Çağlayan M.
europepmc   +1 more source

Opportunistic sampling from the near‐threatened Alexandrine parakeet uncovers genomes of a novel parvovirus and beak and feather disease virus

Australian Veterinary Journal, Volume 103, Issue 7, Page 416-421, July 2025.
Birds are known to harbour a wide range of pathogenic viruses, including the beak and feather disease virus (BFDV; species, Circovirus parrot), which poses a significant threat to the conservation of endangered avian species. This study reports the genomic identification and characterisation of a novel psittaciform chaphamaparvovirus (PsChPV‐6) and ...
S Sarker, N Klukowski, S Talukder, A Athukorala, MJ Uddin   +4 more
wiley   +1 more source

Beyond natural flavonoids: exploring bioisosterism in design and synthesis of influenza endonuclease inhibitors. [PDF]

RSC Med Chem
Reiberger R, Kráľ M, Radilová K, Kotačka T, Dračínský M, Tsalyy A, Brynda J, Majer P, Konvalinka J, Kožíšek M, Machara A.   +10 more
europepmc   +1 more source

The DNA Repair Component EEPD1 Regulates Actin Polymerization

Biology of the Cell, Volume 117, Issue 7, July 2025.
EEPD1 is a DNA repair component important for proper replication. This study demonstrates that EEPD1 is required for phosphorylation of multiple actin polymerization components, SRC, Cortactin, RAC and Profilin. Without EEPD1 cells fail to polymerize actin and lose proper nuclear shape, lamellipodia and cell migration.
Robert Hromas, Austin Kirby, Andrew Carrillo, Aruna Jasiwal, Kimi Kong, Manh Tien Tran, Dominic Arris, Elizabeth A. Williamson   +7 more
wiley   +1 more source

Yatakemycin biosynthesis requires two deoxyribonucleases for toxin self-resistance. [PDF]

RSC Chem Biol
Dorival J, Yuan H, Walker AS, Tang GL, Eichman BF.   +4 more
europepmc   +1 more source