Results 321 to 330 of about 272,760 (374)

Protonated Glutamate and Aspartate Side Chains Can Recognize Phosphodiester Groups via Strong and Short Hydrogen Bonds in Biomacromolecular Complexes

Angewandte Chemie International Edition, Volume 64, Issue 27, July 1, 2025.
The highly negatively charged phosphodiester groups of nucleic acids and cyclic (di‐)nucleotides often interact with amino acids containing polar or positively charged sidechains. Due to charge repulsion with their negatively charged carboxylate groups in their side chains, glutamate and aspartate are considered to be detrimental to such interactions ...
Konstantin Neißner, Elke Duchardt‐Ferner, Christoph Wiedemann, Julian Kraus, Ute A. Hellmich, Jens Wöhnert   +5 more
wiley   +1 more source

Beyond natural flavonoids: exploring bioisosterism in design and synthesis of influenza endonuclease inhibitors. [PDF]

RSC Med Chem
Reiberger R, Kráľ M, Radilová K, Kotačka T, Dračínský M, Tsalyy A, Brynda J, Majer P, Konvalinka J, Kožíšek M, Machara A.   +10 more
europepmc   +1 more source

Correspondence: "Association of CD40 gene polymorphisms and immune thrombocytopenic purpura in the adult Egyptian population". [PDF]

Blood Res
Abdelkreem E.
europepmc   +1 more source

Solid-State Nanopore Real-Time Assay for Monitoring Cas9 Endonuclease Reactivity. [PDF]

ACS Nano
Chau CCC, Weckman NE, Thomson EE, Actis P.   +3 more
europepmc   +1 more source

MRN-CtIP, EXO1, and DNA2-WRN/BLM act bidirectionally to process DNA gaps in PARPi-treated cells without strand cleavage. [PDF]

Genes Dev
Seppa IM, Ceppi I, Tennakoon M, Reginato G, Jackson J, Rouault CD, Agashe S, Sviderskiy VO, Limbu M, Lantelme E, Meroni A, Braunshier S, Borrello D, Verma P, Cejka P, Vindigni A.   +15 more
europepmc   +1 more source

<i>Caulobacter</i> Strains Code for Novel Restriction Endonucleases That Protect Them from Bacteriophage Infections. [PDF]

Viruses
Sisto I, Ely B.
europepmc   +1 more source

Identification and characterization of a dsRNA-degrading nuclease CmdsRNase2 influencing RNAi efficiency in the rice leaffolder Cnaphalocrocis medinalis. [PDF]

Sci Rep
Wang X, Du J, Li S, Li J, Zha R.
europepmc   +1 more source

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Endonucleases

Current Protocols in Molecular Biology, 1989
AbstractReaction conditions for numerous ensonucleases are detailed in this unit along with discussions of potential applications. Specific enzymes include BAL 31 nuclease, S1 nuclease, mung bean nuclease, micrococcal nuclease and DNase I.
Stanley Tabor, Kevin Struhl
openaire   +3 more sources