Results 21 to 30 of about 2,425 (97)
Aggregate, Volume 6, Issue 5, May 2025.Pathogen‐derived extracellular vesicle detection: theoretical insights and advanced methodologies: This review explores the theoretical foundations and practical applications of pEV detection, emphasizing the challenges and innovative strategies involving novel aggregate materials and machine learning for enhanced diagnostic accuracy.
Lihan Lai +6 more
wiley +1 more source
Innovative Wirkstoffe aus der antibakteriellen Forschung im Kampf gegen mikrobielle Resistenzen
Angewandte Chemie, Volume 137, Issue 10, March 3, 2025.Dieser Artikel gewährt einen Überblick über in den letzten drei Jahrzehnten untersuchte antibakteriellen Wirkstoffe. Aspekte der Herkunft, der zellulären Targetstrukturen, des antibakteriellen Wirkspektrums und dem Nachweis der Wirksamkeit in Tierstudien werden zusammen mit aktuellen Entwicklungen beleuchtet.
Roderich D. Süssmuth +3 more
wiley +1 more source
Fighting Antimicrobial Resistance: Innovative Drugs in Antibacterial Research
Angewandte Chemie International Edition, Volume 64, Issue 10, March 3, 2025.This article provides an overview over antibacterial drugs investigated in the past three decades. Aspects of the compound's origins, their cellular targets, the antibacterial spectrum and proof‐of‐concept in animal studies are covered and current trends are highlighted.
Roderich D. Süssmuth +3 more
wiley +1 more source
The Plant Genome, Volume 18, Issue 1, March 2025.Abstract The Septoria tritici blotch (STB) [Zymoseptoria tritici (Desm.)] of wheat (Triticum aestivum L.) is characterized by its polycyclic and hemibiotrophic nature. It is one of the most dangerous diseases affecting wheat production worldwide. Durable resistance is largely decided by the combined effect of several quantitative trait loci (QTLs ...
Manjeet Kumar +5 more
wiley +1 more source
MicroRNA gatekeepers: Orchestrating rhizospheric dynamics
Journal of Integrative Plant Biology, Volume 67, Issue 3, Page 845-876, March 2025.MicroRNAs play a crucial role in plant communication within the rhizosphere, shaping growth, development, and resilience to biotic and abiotic stresses. ABSTRACT The rhizosphere plays a crucial role in plant growth and resilience to biotic and abiotic stresses, highlighting the complex communication between plants and their dynamic rhizosphere ...
Muhammad Fahad +3 more
wiley +1 more source
Wound Repair and Regeneration, Volume 33, Issue 1, January/February 2025.Abstract As the number of patients requiring organ transplants continues to rise exponentially, there is a dire need for therapeutics, with repair and regenerative properties, to assist in alleviating this medical crisis. Over the past decade, there has been a shift from conventional stem cell treatments towards the use of the secretome, the protein ...
Kate Da Silva +2 more
wiley +1 more source
Aquaculture Nutrition, Volume 2025, Issue 1, 2025.Glucoside is the main antinutritional factor (ANF) of rapeseed meal. In the present study, a bacterium with high efficiency in degrading rapeseed glucoside was screened from pond water. The initial concentration of 1.0 × 107 CFU/mL bacterial solution was added to rapeseed meal and fermented for 48 h with a degradation rate of glucoside and ...
Hong-yu Lu +10 more
wiley +1 more source
Study on the mechanism of Shenmai injection in the treatment of sepsis
Journal of Cellular and Molecular Medicine, Volume 28, Issue 22, November 2024.Abstract Shenmai injection (SMI) is widely used in the clinical treatment of sepsis, but its mechanism is not yet clear. This study aimed to explore the molecular mechanism through network pharmacology, bioinformatics, and molecular docking technologies.
Mengxia Yang +4 more
wiley +1 more source
Journal of Peptide Science, Volume 30, Issue 7, July 2024.The development of highly affine, selective peptides and small molecules in recent years has allowed peptide drugs (PDCs) and small molecule–drug conjugates (SMDCs) to increasingly compete with antibody–drug conjugates (ADCs). This review summarises and describes integrin‐addressing PDCs and SMDCs, while highlighting points of great interest.
Jannik Paulus, Norbert Sewald
wiley +1 more source
Comparative proteomics of a versatile, marine, iron‐oxidizing chemolithoautotroph
Environmental Microbiology, Volume 26, Issue 6, June 2024.In this study, we identified proteins that were upregulated under iron‐oxidizing conditions. Notably, we highlight a periplasmic di‐heme cytochrome c that is associated with a putative redox complex spanning the inner membrane, periplasm, outer membrane, and extracellular space.
Roman A. Barco +8 more
wiley +1 more source