Results 41 to 50 of about 3,552 (138)

The paradigm of stem cell secretome in tissue repair and regeneration: Present and future perspectives

Wound Repair and Regeneration, Volume 33, Issue 1, January/February 2025.
Abstract As the number of patients requiring organ transplants continues to rise exponentially, there is a dire need for therapeutics, with repair and regenerative properties, to assist in alleviating this medical crisis. Over the past decade, there has been a shift from conventional stem cell treatments towards the use of the secretome, the protein ...
Kate Da Silva, Pradeep Kumar, Yahya E. Choonara   +2 more
wiley   +1 more source

Multi-omics Reveals the Lifestyle of the Acidophilic, Mineral-Oxidizing Model Species Leptospirillum ferriphilumT. [PDF]

, 2017
Leptospirillum ferriphilum plays a major role in acidic, metal-rich environments, where it represents one of the most prevalent iron oxidizers. These milieus include acid rock and mine drainage as well as biomining operations.
Acosta, Agar, Aliaga Goltsman, Ansgar Poetsch, Antoine Buetti-Dinh, Baker-Austin, Bellenberg, Bellenberg, Bird, Bolger, Bond, Bonnefoy, Borda, Brierley, Buetti-Dinh, Bury-Moné, Bykov, Cardenas, Castro, Cohn, Coram, Cox, Cox, Dopson, Dopson, Dopson, Esparza, Ferrer, Ferrer, Frawley, Fujimura, Gehrke, Goltsman, González, Harneit, Heintz-Buschart, Hengge, Hippe, Hoffman, Hugler, Hunt, Hyatt, Igor V. Pivkin, Imlay, Issotta, Jiang, Jünemann, Kaur, Keiski, Kinnunen, Koskinen, Kotze, Krumsiek, Krzywinski, Köster, Lemire, Leverrier, Li, Liao, Love, M. Julia Pettinari, Mackintosh, Malte Herold, Mangold, Mark Dopson, Markowitz, Mi, Mohamed El Hajjami, Moreno-Paz, Noël, Paul Wilmes, Pitcher, Rappsilber, Richard, Rider, Rohwerder, Roume, Roux, Ruiz, Samartzidou, Sand, Schoonen, Seemann, Slonczewski, Stephan Christel, Sören Bellenberg, Tyanova, Vera, Watling, Wibberg, Wilmes, Wolfgang Sand, Wolstencroft, Yelton, Yu, Zapata, Zhang   +96 more
core   +2 more sources

Biological Characterization and Glucosinolate Degradation Mechanisms of Bacillus subtilis BSY82 in Rapeseed Meal

Aquaculture Nutrition, Volume 2025, Issue 1, 2025.
Glucoside is the main antinutritional factor (ANF) of rapeseed meal. In the present study, a bacterium with high efficiency in degrading rapeseed glucoside was screened from pond water. The initial concentration of 1.0 × 107 CFU/mL bacterial solution was added to rapeseed meal and fermented for 48 h with a degradation rate of glucoside and ...
Hong-yu Lu, An-Ning Shi, Jun Wang, Li-Juan Liu, Jiang-Yi Tang, Ya-Jun Wang, Xue-Zhi Zhu, De-Feng Zhang, Li-Yan Liu, Qing Wang, Lee Seong Wei   +10 more
wiley   +1 more source

Molecular cloning and biochemical characterization of Xaa-Pro dipeptidyl-peptidase from Streptococcus mutans and its inhibition by anti-human DPP IV drugs

, 2016
Streptococcus mutans harbours an intracellular, human DPP IV-analogous enzyme Xaa-Pro dipeptidyl-peptidase (EC 3.4.14.11). According to previous reports, an extracellular isozyme in S. gordonii and S. suis has been associated with virulence.
De, A, Lupidi, Giulio, Petrelli, Dezemona, Vitali, Luca Agostino   +3 more
core   +1 more source

Automatic selection of representative proteins for bacterial phylogeny [PDF]

, 2005
Background Although there are now about 200 complete bacterial genomes in GenBank, deep bacterial phylogeny remains a difficult problem, due to confounding horizontal gene transfers and other phylogenetic "noise".
Goldberg David, Bern Marshall
core   +2 more sources

Study on the mechanism of Shenmai injection in the treatment of sepsis

Journal of Cellular and Molecular Medicine, Volume 28, Issue 22, November 2024.
Abstract Shenmai injection (SMI) is widely used in the clinical treatment of sepsis, but its mechanism is not yet clear. This study aimed to explore the molecular mechanism through network pharmacology, bioinformatics, and molecular docking technologies.
Mengxia Yang, Tengfei Chen, Yue Xu, Qingquan Liu, Xiaolong Xu   +4 more
wiley   +1 more source

Roles of the second messenger cyclic di-GMP in environmental adaptation of Sinorhizobium meliloti [PDF]

, 2017
Bacteria have evolved various systems for the integration of environmental signals to rapidly coordinate cellular pathways and adapt to changes in their environment.
Schäper, Simon
core   +1 more source

Small molecule– and peptide–drug conjugates addressing integrins: A story of targeted cancer treatment

Journal of Peptide Science, Volume 30, Issue 7, July 2024.
The development of highly affine, selective peptides and small molecules in recent years has allowed peptide drugs (PDCs) and small molecule–drug conjugates (SMDCs) to increasingly compete with antibody–drug conjugates (ADCs). This review summarises and describes integrin‐addressing PDCs and SMDCs, while highlighting points of great interest.
Jannik Paulus, Norbert Sewald
wiley   +1 more source

Proteomic alterations of Escherichia coli by paraquat [PDF]

, 2010
Paraquat (PQ; a widely used herbicide) exerts its harmful effect to human, mammals and microorganisms upon intracellular conversion to superoxide radical.
Isarankura-Na-Ayudhya, Chartchalerm, Isarankura-Na-Ayudhya, Patcharee, Polprachum, Wilaiwan, Prachayasittikul, Virapong, Roytrakul, Sittiruk, Singhagamol, Watsarach, Thippakorn, Chadinee, Yainoy, Sakda   +7 more
core  

Drought stress response in winter wheat varieties – changes in leaf proteins and proteolytic activities [PDF]

, 2020
Radiation mutagenesis has been used in sustainable agriculture as a tool for increasing plant variability and providing new lines for selection. This necessitates a comparison, by using suitable stress markers, of the newly created lines with some well ...
Dobrina Pecheva, Elisaveta Kirova, Lyudmila Simova-Stoilova   +2 more
core   +3 more sources