Results 131 to 140 of about 24,423 (298)
Defective Processing of Cytoplasmic and Chloroplast Ribosomal RNA in the Absence of Arabidopsis DXO1
Plant, Cell &Environment, Volume 48, Issue 6, Page 4227-4244, June 2025.ABSTRACT Decapping 5′‐3′ exoribonucleases from the DXO/Rai1 family are highly conserved among eukaryotes and exhibit diverse enzymatic activities depending on the organism. The biochemical and structural properties of the plant DXO1 differ from the yeast and animal counterparts, which is reflected in the in vivo functions of this enzyme.
Monika Zakrzewska‐Placzek +5 more
wiley +1 more source
Frontiers in Microbiology, 2017 Here we identified a functional MazEF-dr system in the exceptionally stress-resistant bacterium D. radiodurans. We showed that overexpression of the toxin MazF-dr inhibited the growth of Escherichia coli.
Tao Li +9 more
doaj +1 more source
Regulation of the human tRNase ZS gene expression [PDF]
, 2008 There are two types of tRNA 3′ processing endoribonucleases (tRNase Z): a short form (tRNase ZS) and a long form (tRNase ZL). Although the human genome contains both genes, little is known about the physiological role of tRNase ZS.
Nashimoto, Masayuki +2 more
core +1 more source
The FASEB Journal, Volume 39, Issue 10, 31 May 2025.A proposed model showed that the RNA binding proteins MCPIP2 and IGF2BP1 competitively regulate the stability and expression of proangiogenic transcripts in tumor cells. MCPIP2 decays proangiogenic mRNAs by binding to the conserved stem–loop structure in the 3ʹ UTR via its RNase domain, resulting in inhibition of proangiogenic gene expression and ...
Wenbao Lu +4 more
wiley +1 more source
RETRACTED: The RasGAP-associated endoribonuclease G3BP assembles stress granules [PDF]
The Journal of Cell Biology, 2003 Stress granules (SGs) are formed in the cytoplasm in response to various toxic agents, and are believed to play a critical role in the regulation of mRNA metabolism during stress. In SGs, mRNAs are stored in an abortive translation initiation complex that can be routed to either translation initiation or degradation.
Jamal Tazi +6 more
openaire +3 more sources
Subcellular partitioning of MRP RNA assessed by ultrastructural and biochemical analysis. [PDF]
, 1994 A small RNA encoded within the nucleus is an essential subunit of a RNA processing endonuclease (RNase MRP) hypothesized to generate primers for mitochondrial DNA replication from the heavy strand origin of replication.
Gonzalez, M +6 more
core
A secreted endoribonuclease ENDU-2 from the soma protects germline immortality in C. elegans
bioRxiv, 2020 Multicellular organisms coordinate tissue specific response to environmental information via both cell-autonomous and non-autonomous mechanisms. In addition to secreted ligands, secreted small RNAs have recently been reported to regulate gene expression ...
Wenjing Qi +8 more
semanticscholar +1 more source
Controlling mRNA stability and translation with the CRISPR endoribonuclease Csy4 [PDF]
RNA, 2015 The bacterial CRISPR endoribonuclease Csy4 has recently been described as a potential RNA processing tool. Csy4 recognizes substrate RNA through a specific 28-nt hairpin sequence and cleaves at the 3′ end of the stem. To further explore applicability in mammalian cells, we introduced this hairpin at various locations in mRNAs derived from reporter ...
William F. Marzluff +5 more
openaire +3 more sources
Frontiers in Microbiology, 2018 Toxin-antitoxin (TA) systems are implicated in prokaryotic stress adaptation. Previously, bioinformatics analysis predicted that such systems are abundant in some slowly growing chemolithotrophs; e.g., Nitrosomonas europaea.
Tatsuki Miyamoto +10 more
doaj +1 more source
Advanced Science, Volume 12, Issue 18, May 15, 2025.Traditional Chinese Medicine (TCM), while holistic and historically esteemed, faces challenges in “miracle cures” due to slow onset, long cycles, and difficulty controlling quality. This study obtains the active ingredients, glabridin (GLA) and puerarin (PUE), from Ge‐Gen Decoction (GGD), developing a safe and effective drug delivery system, GLA‐PUE ...
Jianhong Qi +7 more
wiley +1 more source