Results 41 to 50 of about 24,423 (298)
The Continuing Story of Endoribonuclease III [PDF]
Microbial Physiology, 2004 Endoribonuclease III (RNase III) plays an important role in the processing of rRNA and mRNAs. It is timely to summarize the most relevant insights obtained during the last years stemming from RNase III. With this aim, the present mini-review provides a wealth of new information focusing on the distribution and architecture of RNase III, substrate ...
Ciarán Condon, Djamel Drider
openaire +2 more sources
bioRxiv, 2021 SARS-CoV-2 is responsible for COVID-19, a human disease that has caused over 2 million deaths, stretched health systems to near-breaking point and endangered the economies of countries and families around the world.
Berta Canal +13 more
semanticscholar +1 more source
Crystals, 2017 The CRISPR-associated protein 6, Cas6 protein, is an endoribonuclease that cleaves precursor CRISPR RNAs within the repeat sequence to release specific invader-targeting RNAs. Cas6 protein can recognize different sequences by their specific scaffold.
Ming-Chang Lee +13 more
doaj +1 more source
Drosophila CG3303 is an essential endoribonuclease linked to TDP-43-mediated neurodegeneration [PDF]
, 2017 Endoribonucleases participate in almost every step of eukaryotic RNA metabolism, acting either as degradative or biosynthetic enzymes. We previously identified the founding member of the Eukaryotic EndoU ribonuclease family, whose components display ...
BOZZONI, Irene +11 more
core +1 more source
Journal of Medicinal Chemistry, 2021 To develop antiviral therapeutics against human coronavirus (HCoV) infections, suitable coronavirus drug targets and corresponding lead molecules must be urgently identified.
Annelies Stevaert +11 more
semanticscholar +1 more source
Inhibition of HIV-1 Viral Infection by an Engineered CRISPR Csy4 RNA Endoribonuclease. [PDF]
PLoS ONE, 2015 The bacterial defense system CRISPR (clustered regularly interspaced short palindromic repeats) has been explored as a powerful tool to edit genomic elements.
Rui Guo +5 more
doaj +1 more source
Regulated Inositol‐Requiring Protein 1‐Dependent Decay as a Mechanism of Corin RNA and Protein Deficiency in Advanced Human Systolic Heart Failure [PDF]
, 2014 BACKGROUND: The compensatory actions of the endogenous natriuretic peptide system require adequate processing of natriuretic peptide pro‐hormones into biologically active, carboxyl‐terminal fragments.
Barton, P +5 more
core +1 more source
The endoplasmic reticulum in plant immunity and cell death [PDF]
, 2012 The endoplasmic reticulum (ER) is a highly dynamic organelle in eukaryotic cells and a major production site of proteins destined for vacuoles, the plasma membrane, or apoplast in plants.
Eichmann, Ruth, Schäfer, P. (Patrick)
core +9 more sources
Structure, Evolution, and Functions of Bacterial Type III Toxin-Antitoxin Systems
Toxins, 2016 Toxin-antitoxin (TA) systems are small genetic modules that encode a toxin (that targets an essential cellular process) and an antitoxin that neutralises or suppresses the deleterious effect of the toxin.
Nathalie Goeders +4 more
doaj +1 more source
The inhibition of IRE1alpha/XBP1 axis prevents EBV-driven lymphomagenesis in NSG mice
Microbiology Spectrum, 2023 Post-transplant lymphoproliferative disorders (PTLD) are a group of heterogeneous diseases originating in conditions of immune deficiency, whose main driver is considered to be Epstein-Barr virus (EBV).
Andrea Arena +9 more
doaj +1 more source