Results 81 to 90 of about 22,926 (249)
Hfq binding changes the structure of Escherichia coli small noncoding RNAs OxyS and RprA, which are involved in the riboregulation of rpoS [PDF]
OxyS and RprA are two small noncoding RNAs (sRNAs) that modulate the expression of rpoS, encoding an alternative sigma factor that activates transcription of multiple Escherichia coli stress-response genes. While RprA activates rpoS for translation, OxyS
Callaghan, Anastasia +9 more
core +1 more source
Tipiracil binds to uridine site and inhibits Nsp15 endoribonuclease NendoU from SARS-CoV-2
Youngchang Kim, Jacek Wower, and colleagues explore the sequence specificity, metal ion dependence and catalytic mechanism of the Nsp15 endoribonuclease NendoU from SARS-CoV-2.
Youngchang Kim +10 more
doaj +1 more source
Dapagliflozin rescues endoplasmic reticulum stress-mediated cell death. [PDF]
学位記番号 ...
Shibusawa, Ryo +2 more
core
A PAS domain-containing regulator controls flagella-flagella interactions in Campylobacter jejuni [PDF]
The bipolar flagella of the foodborne bacterial pathogen Campylobacter jejuni confer motility, which is essential for virulence. The flagella of C. jejuni are post-translationally modified, but how this process is controlled is not well understood.
Arnoud H M Van Vliet +6 more
core +5 more sources
Cleavage sequence specificity of Nsp15
Nsp15 is an EndoU nuclease that is partially responsible for SARS-CoV-2’s ability to evade the immune system response. Despite its importance, the sequence specificity of Nsp15 remains difficult to fully determine.
John V. McGuire, Scott Horowitz
doaj +1 more source
Impact of alternative carbon sources and antifungal treatment on Candida glabrata biofilms transcription profile [PDF]
Candida glabrata is considered a major opportunistic fungal pathogen of humans and has emerged as a leading cause of nosocomial fungal infections. The capacity of this yeast species to cause infections is dependent on the ability to grow within the human
Alves, Rosana +8 more
core +1 more source
Protease‐mediated maturation of M‐PMV reverse transcriptase into a functional heterodimer
Abstract Reverse transcriptase (RT) of retroviruses orchestrates viral replication, yet its structural diversity remains poorly understood. Well‐studied RTs, such as those from HIV‐1, murine leukemia virus, and avian myeloblastosis virus, were characterized decades ago, but less prominent retroviruses have escaped detailed analysis.
Marina Kapisheva +6 more
wiley +1 more source
Processing Endoribonucleases and mRNA Degradation in Bacteria [PDF]
Volume 184, no. 17, p. 4645-4657, 2002. Page 4647, column 1, lines 42-45: The sentence should read “For example, one message in the T7 early polycistronic mRNA, as well as a few late messages, yields increased protein from RNase III cleavage while the others are not affected by such cleavages (41).”
openaire +3 more sources
This review illustrates how intracellular bacterial pathogens—such as Brucella, Mycobacterium tuberculosis, and Legionella—secrete effector proteins that specifically target the IRE1α, PERK, and ATF6 branches of the unfolded protein response (UPR) to hijack ER stress signaling.
Enhui Dai +5 more
wiley +1 more source
The S100A4/STAT3 axis promotes Rmrp transcription in AEC‐IIs and Rmrp expression in AEC‐II‐derived exosomes. Upon entry into AMs, Rmrp binds to and blocks the ubiquitination and degradation of ZFP36. Increased ZFP36 induced Pfkfb3 mRNA decay by binding to AREs in the 3′ UTR, curbing glycolysis and immune responses of AMs and aggravating SII and ...
Chengxi Liu +17 more
wiley +1 more source

