Functional Mapping of AGO-Associated Zika Virus-Derived Small Interfering RNAs in Neural Stem Cells
Frontiers in Cellular and Infection Microbiology, 2021 Viral interfering RNA (viRNA) has been identified from several viral genomes via directly deep RNA sequencing of the virus-infected cells, including zika virus (ZIKV).
Jianxiong Zeng +14 more
doaj +1 more source
Dapagliflozin rescues endoplasmic reticulum stress-mediated cell death. [PDF]
, 2019 学位記番号 ...
Shibusawa, Ryo +2 more
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Hot and crispy : CRISPR-Cas systems in the hyperthermophile Sulfolobus solfataricus [PDF]
, 2013 The CRISPR (clustered regularly interspaced short palindromic repeats) and Cas (CRISPR-associated) genes are widely spread in bacteria and archaea, representing an intracellular defence system against invading viruses and plasmids.
White, Malcolm F., Zhang, Jing
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ESSENTIAL MEIOTIC ENDONUCLEASE 1 is required for chloroplast development and DNA repair in rice
Plant Biotechnology Journal, Volume 23, Issue 7, Page 2931-2948, July 2025.Summary Chloroplast development is fundamental to photosynthesis and plant growth but is sensitive to environmental stress. Chloroplast development and division require genome stability and DNA repair, but the underlying mechanisms have been unclear. Using a forward genetic approach, we identified the striped‐leaf mutant k48 in the rice (Oryza sativa L.
Yanxin Du +5 more
wiley +1 more source
Cleavage sequence specificity of Nsp15
RNA BiologyNsp15 is an EndoU nuclease that is partially responsible for SARS-CoV-2’s ability to evade the immune system response. Despite its importance, the sequence specificity of Nsp15 remains difficult to fully determine.
John V. McGuire, Scott Horowitz
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Hfq binding changes the structure of Escherichia coli small noncoding RNAs OxyS and RprA, which are involved in the riboregulation of rpoS [PDF]
, 2013 OxyS and RprA are two small noncoding RNAs (sRNAs) that modulate the expression of rpoS, encoding an alternative sigma factor that activates transcription of multiple Escherichia coli stress-response genes. While RprA activates rpoS for translation, OxyS
Callaghan, Anastasia +9 more
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Alkane biosynthesis gene expression and its increased production in recombinant cyanobacteria
FEBS Open Bio, Volume 15, Issue 6, Page 949-962, June 2025.The transcription and mRNA structures of the alkane biosynthesis genes ado/aar were analysed in the representative cyanobacteria PCC 6803 and SK1‐2‐1, which produce C17H36 and C15H32, respectively. PCC 6803 transconjugants carrying these genes showed a 1.8‐ to 2.3‐fold increase in C17H36 production.
Misato Nagao +4 more
wiley +1 more source
Homodimerisation-independent cleavage of dsRNA by a pestiviral nicking endoribonuclease [PDF]
Scientific Reports, 2018 AbstractThe glycoprotein Erns plays a central role in the biology of the pestivirus bovine viral diarrhea virus (BVDV). This soluble endonuclease mediates the escape from an interferon (IFN) response in the infected fetus, thereby permitting the establishment of persistent infection. Viral single-stranded (ss) and double-stranded (ds) RNA act as potent
Carmela Lussi +2 more
openaire +3 more sources
5′ DREDGE: Direct Repeat-Enabled Downregulation of Gene Expression via the 5′ UTR of Target Genes
CellsDespite the availability of numerous methods for controlling gene expression, there remains a strong need for technologies that maximize two key properties: selectivity and reversibility.
Sagar J. Parikh +6 more
doaj +1 more source
Impact of alternative carbon sources and antifungal treatment on Candida glabrata biofilms transcription profile [PDF]
, 2016 Candida glabrata is considered a major opportunistic fungal pathogen of humans and has emerged as a leading cause of nosocomial fungal infections. The capacity of this yeast species to cause infections is dependent on the ability to grow within the human
Alves, Rosana +8 more
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