Results 41 to 50 of about 8,924 (196)

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

British Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli, Emanuela Micioni Di Bonaventura, Giacomo Einaudi, Gustavo Provensi, Alessia Costa, Claudio D'Addario, Carlo Cifani, Maria Vittoria Micioni Di Bonaventura   +7 more
wiley   +1 more source

The psychophysiology of music-based interventions and the experience of pain

Frontiers in Psychology
In modern times there is increasing acceptance that music-based interventions are useful aids in the clinical treatment of a range of neurological and psychiatric conditions, including helping to reduce the perception of pain.
Carolyn A. Arnold, Carolyn A. Arnold, Matthew K. Bagg, Matthew K. Bagg, Matthew K. Bagg, Matthew K. Bagg, Alan R. Harvey, Alan R. Harvey   +7 more
doaj   +1 more source

From morphine to endogenous opioid peptides, e.g., endorphins: the endless quest for the perfect painkiller

Substantia, 2018
Opium was known since the Neolithic era and in 5th century wild Papaver use was reported to induce sleep and relieving pain. First active component isolated from Opium was morphine, the paradigm of a natural product discovered 150 years before isolation ...
Anna Maria Papini
doaj   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Challenges and new opportunities for detecting endogenous opioid peptides in reward

Addiction Neuroscience, 2022
The endogenous opioid peptide system, comprised of enkephalins, endorphins, dynorphins, and nociceptin, is a highly complex neurobiological system. Opioid peptides are derived from four precursor molecules and undergo several processing events yielding ...
Sineadh M. Conway, Marwa O. Mikati, Ream Al-Hasani   +2 more
doaj   +1 more source

Opioids in breast cancer: Between analgesia and modulation of tumour progression

British Journal of Pharmacology, EarlyView.
Preclinical investigations consistently demonstrate that activation of μ‐opioid receptors and δ‐opioid receptors promote proliferation, migration, angiogenesis, epithelial‐mesenchymal transition, acquisition of cancer stem cell phenotypes, and chemoresistance.
Marianna Ciwun, Anna Tankiewicz‐Kwedlo, Dariusz Pawlak   +2 more
wiley   +1 more source

Efficacy and welfare effects of different forms of physical restraint for upper airway endoscopy of horses

Equine Veterinary Journal, EarlyView.
Abstract Background Physical restraint of horses for veterinary procedures is necessary to allow completion of tasks effectively and without injury to patient or personnel. Objectives To compare physiological effects and behavioural responses to four commonly used restraint techniques for upper respiratory tract (URT) endoscopy in unsedated horses ...
Claire O'Brien, Olivier Simon, Samantha H. Franklin, Gustavo Ferlini Agne, Sarah Weaver, Sharanne L. Raidal   +5 more
wiley   +1 more source

Beyond Bouncing Back: Exploring Undergraduate Dental Professional Students' Perceptions of Resilience

International Journal of Dental Hygiene, EarlyView.
ABSTRACT Introduction The first signs of mental health issues in dentistry manifest as early as undergraduate training, thus it is essential to delve into the concept of resilience to equip those studying and working in dentistry with the resources to cultivate a positive mindset.
Vaida Kaunaite, Marina Harris
wiley   +1 more source

Endorphins, Exercise, and Addictions: A Review of Exercise Dependence [PDF]

Impulse: The Premier Undergraduate Neuroscience Journal, 2006
Endorphins are endogenous opioids released from the pituitary gland that are believed to mediate analgesia, induce euphoria, and play a role in the reward system in the brain. It has been suggested that endorphins are responsible for creating the relaxed
Andrea Leuenberger
doaj  

Hyperthermia and endorphins

Biomedicine & Pharmacotherapy, 1993
This paper discusses the role of endogenous opioids in response to hyperthermia and the alterations observed in drug or alcohol addicts. Endorphins, rather than enkephalins are involved in adaptation to heat in the central nervous system. The pituitary secretion of beta endorphin together with ACTH in response to thermal stress provided the opportunity
P P, Vescovi, V, Coiro
openaire   +2 more sources