Results 41 to 50 of about 401,605 (317)

Remnant cholesterol, a potential risk factor of metabolic dysfunction-associated fatty liver disease

Nutrition & Metabolism
Objectives This study aimed to explore the association between remnant cholesterol and metabolic dysfunction-associated fatty liver disease (MAFLD) in an adult population in the United States.
Xuanyu Hao, Dongyang Li, Xingyong Huang, Tingting Wang, Peng Wu, Lufan Shen, Kai Zhang, Siyu Sun   +7 more
doaj   +1 more source

A Novel Decellularized Fibrocartilage Graft Promotes Tympanic Membrane Repair

Advanced Healthcare Materials, EarlyView.
An off‐the‐shelf decellularized porcine meniscus fibrocartilage graft (MEND) is engineered for pediatric tympanoplasty. Featuring a microchannel architecture that promotes host cell invasion, MEND rapidly closes tympanic membrane perforations and fully remodels in vivo, outperforming fascia and matching cartilage grafts while avoiding donor‐site ...
Paul M. Gehret, Ryan M. Friedman, Gautham Nair, Stephanie L. Fung, Dana D. Ragbirsingh, John Germiller, Riccardo Gottardi   +6 more
wiley   +1 more source

Development and validation of a disulfidptosis-related prognostic model for colorectal cancer using multi-omics analysis

Discover Oncology
This study aims to integrate multi-omic and clinical data concerning disulfidptosis-related genes (DRGs) to facilitate molecular typing and prognosis in colorectal cancer (CRC).
Lei Shi, Huimei Wang, Yongxiao Sun, Na Xu, Aiyue Pei, Nan Zhang   +5 more
doaj   +1 more source

Early increase in blood supply (EIBS) is associated with tumor risk in the Azoxymethane model of colon cancer

BMC Cancer, 2018
Background The present study aimed to investigate the role of blood supply in early tumorigenesis in colorectal cancer. We leveraged the renin angiotensin system (RAS) to alter colonic blood supply and determine the effect on tumor initiation and ...
Sarah Ruderman, Adam Eshein, Vesta Valuckaite, Urszula Dougherty, Anas Almoghrabi, Andrew Gomes, Ajaypal Singh, Baldeep Pabla, Hemant K. Roy, John Hart, Marc Bissonnette, Vani Konda, Vadim Backman   +12 more
doaj   +1 more source

Clinical comparison of percutaneous transforaminal endoscopic discectomy and unilateral biportal endoscopic discectomy for single-level lumbar disc herniation

Frontiers in Surgery, 2023
PurposeTo compare the clinical outcomes of percutaneous transforaminal endoscopic discectomy (PTED) and unilateral biportal endoscopic discectomy (UBE) for the treatment of single-level lumbar disc herniation (LDH).Materials and methodsFrom January 2020 ...
Xiaokang Cheng, Xiaokang Cheng, Beixi Bao, Yuxuan Wu, Yuanpei Cheng, Chunyang Xu, Yang Ye, Chentao Dou, Bin Chen, Hui Yan, Jiaguang Tang   +10 more
doaj   +1 more source

Endoscopic Ear Surgery for Congenital Cholesteatoma in Children

, 2022
Background: Endoscopic ear surgery is a promising technique for removing congenital cholesteatoma in children. It can provide greater visual access to hidden areas of the middle ear and facilitate middle-ear manipulation.
Woo Seok Kang, Min Young Kwak, Yeonjoo Choi, Jong Woo Chung   +3 more
core   +1 more source

Rapid Fabrication of Self‐Propelled and Steerable Magnetic Microcatheters for Precision Medicine

Advanced Materials, EarlyView.
A rapid Joule heating fabrication method for the production of self‐propelling, adaptive microcatheters, with tunable stiffness and integrated microfluidic channels is presented. Demonstrated through three microrobotic designs, including a steerable guiding catheter, an untethered wave‐crawling TubeBot, and a distal‐end propelled microcatheter, it was ...
Zhi Chen, Boris Rivkin, David Castellanos‐Robles, Ivan Soldatov, Lukas Beyer, Mariana Medina‐Sánchez   +5 more
wiley   +1 more source

Sex-related association between smoke exposure and gallstones in a US population: a cross-sectional study

BMC Public Health
Background Cholelithiasis are a condition that creates an economic and medical burden on society, and women are more susceptible to gallbladder stones. However, the effect of smoking on the development of gallstones remains controversial.
Xingyong Huang, Xuanyu Hao, Tingting Wang, Xiaoyue Zhang, Peng Wu, Lufan Shen, Yuanyuan Yang, Wanchuan Zhang, Kai Zhang   +8 more
doaj   +1 more source

Turning Unpredictable Biomolecule Adsorption to Controlled Corona Formation: Focus on Carbon Nanomaterials

Advanced Materials, EarlyView.
Controlling the protein corona formation onto carbon nanomaterials (CNMs) enhances their functionalities as platforms for cancer theranostics. Here, we reviewed the effects of the intrinsic and acquired properties of CNMs on protein corona formation, the consequent biological and toxicological outcomes, and the strategies to reshape corona formation ...
Yajuan Zou, Yalei Hu, Jie Yu, Naoki Komatsu, Yuta Nishina, Alberto Bianco   +5 more
wiley   +1 more source

Fusobacterium mortiferum and its metabolite 5-aminovaleric acid promote the development of colorectal cancer in obese individuals through Wnt/β-catenin pathway by DKK2

Gut Microbes
Colorectal cancer (CRC) is one of the most prevalent cancers worldwide, with high incidence and mortality rates. An increasing body of research suggests that obesity is a significant risk factor for the development of CRC.
Jiaxin Deng, Jiawei Zhang, Mingli Su, Juan Li, Yuping Su, Qinghua Zhong, Jiancong Hu, Yongcheng Chen, Sen Liao, Dezheng Lin, Xuefeng Guo   +10 more
doaj   +1 more source