Results 81 to 90 of about 1,668,803 (258)

Clinical Longitudinal Evaluation After Regimen Stop (CLEAR) of Dupilumab in Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Long‐term management strategies for severe chronic rhinosinusitis with nasal polyps (CRSwNP) increasingly include biologic therapy targeting Type 2 inflammation. However, data on outcomes after complete discontinuation of dupilumab following sustained disease control are scarce.
Patrick Huber, Manuel Lasch, Veronika Volgger, Clemens Stihl, Philipp Teupe, Fabienne Oettgen, Sophia Gantner, Moritz Gröger   +7 more
wiley   +1 more source

Patient satisfaction with endoscopic ear surgery technique: a comparative study with the postauricular incision microscopic technique

The Egyptian Journal of Otolaryngology
Background Endoscopic ear surgery has numerous benefits, such as the capacity to obtain high-resolution pictures and visualize normally inaccessible locations such as the retrotympanum, sinus tympani, and facial recess.
Osama Metwaly, Mohamed Salah, Abdelrahman Ali   +2 more
doaj   +1 more source

The first Malaysian experience on totally endoscopic ear surgery

Proceedings of Singapore Healthcare, 2020
Introduction: Totally endoscopic ear surgery (TEES) is defined as exclusive application of endoscope transcanally in otologic surgery. This study is aimed to highlight indications and ear pathologies for TEES.
Khairunnisak Misron, Tengku Mohamed Izam Tengku Kamalden   +1 more
doaj   +1 more source

Factors affecting the learning curve in endoscopic ear surgery: experience, training and case selection

The Egyptian Journal of Otolaryngology
Introduction Hundreds of studies have been conducted on the overall success of endoscopic ear surgery over the traditional microscopic technique, prompting further usage of the endoscope.
Osama Metwaly
doaj   +1 more source

Microbial‐Metabolite Signatures Are Associated With Glucocorticoid Responsiveness in Chronic Rhinosinusitis With Nasal Polyps

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Patients with chronic rhinosinusitis with nasal polyps (CRSwNP) exhibit heterogeneous responses to oral glucocorticoids (GCs), but the biological basis of this variability remains unclear. Objective To identify gut microbiome‒plasma metabolomic signatures associated with GC responsiveness in CRSwNP patients and to compare their ...
Ying‐Ying Zhang, Xin‐Yu Ding, Mei‐Ping Lu, Yan‐Bing Chen, Ye Yuan, Lin Jiang, Min Zhang, Lei Cheng   +7 more
wiley   +1 more source

Remote Screening for Age‐Related Olfactory Dysfunction Using the 4‐Item Concise Aging Adults Smell Test

International Forum of Allergy &Rhinology, EarlyView.
Zachary M. Soler, Daniel Giles, Mathew J. Gregoski, Rodney J. Schlosser   +3 more
wiley   +1 more source

Development and Reliability Testing of the Sinonasal Assessment of Reepithelialization, a Novel Wound Healing Scale to Assess Postoperative Healing

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Sinus and skull base surgery create areas of demucosalized bone and cartilage in the sinonasal cavity, yet no standardized system exists to describe the progressive healing of these wounds. The goal of this study was to develop the novel Sinonasal Assessment of Reepithelialization (SNARE) and perform parametric testing including ...
Rohan Bellary, Zakaria Dairi, Niraj Rama, Jennifer Kreinik, Thomas S. Higgins, Taylor Carle, Arthur W. Wu, Dilpreet Mann, Jennifer K. Mulligan, Brian Lobo, Christopher Ito, Elisa A. Illing, Satyan B. Sreenath, Martin J. Citardi, Christopher Roxbury, Raj Sindwani, Edward McCoul, Jeffrey Suh, Daniel Beswick, Philip G. Chen, Dennis M. Tang   +20 more
wiley   +1 more source

Impact of Highly Effective Modulator Therapy on Olfactory‐Specific Gene Expression in People With Cystic Fibrosis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis is common in people with cystic fibrosis (PwCF). Highly effective modulator therapy (HEMT) has been shown to improve sinonasal outcomes. However, prior studies failed to show improvement in objective olfaction with HEMT, and the impact of HEMT on olfactory‐specific quality of life has yet to be studied ...
Michael R. Xiang, Ankit Chauhan, Gina Hong, Denis Hadjiliadis, Daniel Dorgan, Michael M. Rey, Samantha Kane, James N. Palmer, Nithin D. Adappa, Noam A. Cohen, Michael A. Kohanski, Jennifer E. Douglas   +11 more
wiley   +1 more source

The feasibility of endoscopic stapes surgery: A three‐dimensional planning method

Laryngoscope Investigative Otolaryngology
Objective The primary aim of this study was to investigate the accuracy of a semi‐automatic algorithm in assessing the feasibility and complexity of endoscopic stapes surgery preoperatively.
Maaike Jellema, Mijs Buter, Esther E. Blijleven, Koen Willemsen, H. Chien Nguyen, Robert J. Stokroos, Inge Wegner, Henricus G. X. M. Thomeer   +7 more
doaj   +1 more source

Biologics Adoption in CRSwNP and the Associated Decline in Endoscopic Sinus Surgery: A Longitudinal Claims Database Study

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Biologic treatments were introduced for chronic rhinosinusitis with nasal polyps (CRSwNP) in 2019. Treatment algorithms for medically refractory CRSwNP remain open, with patients choosing among surgery, biologics, or both. Real‐world utilization of surgery and biologics remains incompletely characterized.
Stephanie Shintani Smith, Sam L. Kaefer, Harsh Duvvuru, Robert C. Kern, Brent A. Senior, Vijay R. Ramakrishnan   +5 more
wiley   +1 more source