Results 81 to 90 of about 204,639 (266)

Success of Systemic Methotrexate Administration Versus Laparoscopic Salpingostomy in Ectopic Pregnancy

open access: yesGynecology Obstetrics & Reproductive Medicine, 2011
OBJECTIVE: In this study, we tried to compare the efficacies of laparoscopic salpingostomy and medication with a single dose of Methotrexate (50mg/m2) in ectopic pregnancy to determine the differences between the two methods in terms of treatment ...
Özlem Gün Eryılmaz   +5 more
doaj  

Enteric ChAT‐Expressing Neurons Mediate the Protective Effect of Lactobacillus plantarum in Inflammatory Bowel Disease

open access: yesAdvanced Science, EarlyView.
In colitis patients and mice, reduced Lactobacillus abundance is observed. Experimental studies show that L. plantarum A736 metabolizes dietary tryptophan into indole‐3‐lactic acid (ILA), while both L. plantarum A736 and ILA impact ChAT‐expressing enteric neurons and acetylcholine levels, thereby regulating intestinal immune responses and alleviating ...
Bing Xia   +15 more
wiley   +1 more source

A Preclinical Multifunctional Capsule Robot with Unified Diagnosis and Targeted Thermal Therapy for Gastrointestinal Diseases

open access: yesAdvanced Science, EarlyView.
A proof‐of‐concept multifunctional capsule robot integrates diagnostic imaging, magnetic navigation, wireless power transfer, and targeted thermotherapy for gastrointestinal applications. Magnetically guided positioning and stable wireless power enable localized thermal ablation, achieving controlled heating and high cell mortality in vitro.
Heng Zhang   +7 more
wiley   +1 more source

Gastric greater curvature plication combined with Nissen fundoplication in the treatment of gastroesophageal reflux disease and obesity

open access: yesMedicina, 2016
Background and aim: Established anti-reflux procedures such as fundoplications are less efficient in obese patients. The aim of this study was to investigate clinical effectiveness of the fundoplication combined with gastric greater curvature plication ...
Oral Ospanov   +2 more
doaj   +1 more source

Acid‐Responsive Nanobot‐Integrated Core‐Shell Microneedles Reprogram the Degenerative Annulus Fibrosus Microenvironment Through Epigenetic Suppression of Ferroptosis

open access: yesAdvanced Science, EarlyView.
An acid‐responsive core‐shell microneedle system normalizes the degenerative annulus fibrosus microenvironment by consuming pathological H+, generating O2, and providing NIR‐amplified redox buffering. Mechanistically, it epigenetically suppresses ferroptosis via DNMT3A‐dependent methylation of the ATF3 promoter, relieving ATF3‐mediated repression of ...
Lu Tan   +7 more
wiley   +1 more source

The differences in microbial composition may be an important cause of pancreatic pseudocyst infection—an observational study based on 16SrRNA

open access: yesFrontiers in Microbiology
BackgroundThere are no studies of pancreatic pseudocyst infections related to microorganisms. The purpose of this study was to analyze the microbiological differences between infective and non-infective pseudocysts.MethodsThis was an observational cohort
Yaoting Li   +3 more
doaj   +1 more source

Bio‐Memristor Based on Clinical Bile Samples: A Proof‐of‐Concept Pilot Study for Detection of Gallbladder Cancer

open access: yesAdvanced Science, EarlyView.
In this work, we present a bile‐based memristor hardware framework that enables direct, label‐free identification of cholelithiasis and gallbladder cancer at the device level. The Ag/bile/FTO memristor features stable resistive switching and disease‐specific electrical responses, providing a conceptual foundation for circuits and an integrated ERCP ...
Junming Zhu   +17 more
wiley   +1 more source

The Impact of Time Interval to Surgery After Neoadjuvant Chemoradiotherapy on Oncological Outcomes: A Long‐Term Follow‐Up Study on Rectal Cancer Patients

open access: yesCancer Reports
Background Neoadjuvant chemoradiotherapy (nCRT) has been shown to improve prognosis in patients with locally advanced rectal cancer (LARC). However, there is still debate regarding the optimal time of surgery following nCRT.
Marzieh Rahimi   +6 more
doaj   +1 more source

Topological Quantum Biomaterials Enable Pyroptosis‐Senescence Coupling for Enhanced Colorectal Cancer Therapy

open access: yesAdvanced Science, EarlyView.
This work reports conceptually unprecedented topological quantum biomaterials derived from engineered Pd3Sn nanostrips for oncological applications. Their near‐Fermi‐level electronic architecture and superior interfacial charge transport facilitate ultrasound‐amplified redox reactions and efficient ROS generation.
Zilu Chen   +10 more
wiley   +1 more source

An Expertise Transfer Framework For Autonomous Surgical Assistance

open access: yesAdvanced Science, EarlyView.
This study introduces an expertise transfer framework for procedure‐spanning autonomous surgical assistance. By emulating expert logic through hierarchical perception, attention modeling, and knowledge graph‐based decision‐making, the system provides near‐expert surgical view assistance.
Yuan Gao   +12 more
wiley   +1 more source

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