Results 91 to 100 of about 25,057,042 (262)

Rapamycin and Chloroquine Modulate Insulin Resistance and Hepatic Steatosis in a High-Fat/High-Cholesterol Diet-Induced Metabolic Dysfunction-Associated Steatotic Liver Disease Mouse Model

Diabetes, Metabolic Syndrome and Obesity
Qi Liu,1,* Qian Du,2,* Xiaolu Yuan,3 Ting Zhang,3 Jiajing Li,3 Jingyu Xu,4 Rui Xie2 1Department of Gastroenterology, Zhejiang Provincial People’s Hospital Bijie Hospital, Bijie, Guizhou, People’s Republic of China; 2Department of ...
Liu Q, Du Q, Yuan X, Zhang T, Li J, Xu J, Xie R   +6 more
doaj  

Migration‐Associated Variation in Gastric Cancer Risk in the United States: Implications for Risk Stratification

International Journal of Cancer, EarlyView.
This study provides contemporary, population‐based evidence that migration‐associated differences in gastric cancer risk, first described decades ago, remain stable, quantifiable, and prevention‐relevant in the United States. By integrating modern cancer registry data with formal trend analysis and conditional extrapolation, the authors show that ...
Chul S. Hyun, Rong Wang, Sung Hwi Hong, Xuehong Zhang, Jae Il Shin   +4 more
wiley   +1 more source

Acute esophageal necrosis, black esophagus: a case report

Iatreia, 2016
Acute esophageal necrosis, or black esophagus, is a rare syndrome affecting sick elderly patients, with high mortality rate. Its clinical expression is gastrointestinal bleeding.
Ramírez-Quintero, Juan David, Bernal-Sierra, Elisa, Gómez-Rueda, Narly Viviana   +2 more
doaj   +1 more source

Evaluation of Mutation Risk Using Patient‐Derived Organoids in Patients With Lynch Syndrome

International Journal of Cancer, EarlyView.
ABSTRACT Lynch syndrome (LS) is a hereditary cancer predisposition syndrome caused by germline mutation of DNA mismatch repair (MMR) genes, most notably associated with colorectal cancer. Although LS patients face high risk of CRC, risk can vary even among those with the same pathogenic MMR germline mutations. We suggest a functional assay platform for
Youmi Shin, Dong Keon Kim, Yoojeong Seo, Hyeon Hee Lee, Jihye Park, Soo Jung Park, Jae Jun Park, Jae Hee Cheon, Jongwon Oh, Sanghoo Lee, Tae Il Kim   +10 more
wiley   +1 more source

Degree of swallowing impairment in the elderly: clinical and instrumental assessment

Brazilian Journal of Otorhinolaryngology
Objective: To classifying the degree of swallowing impairment in the elderly, comparing clinical and instrumental assessment. Methods: This is a cross-sectional study with quantitative and qualitative analysis of clinical and instrumental assessment of ...
Tatiane Totta Salgado, Cris Magna dos Santos Oliveira, Marina Gatti, Roberta Gonçalves da Silva, Heitor Marques Honório, Giédre Berretin-Felix   +5 more
doaj   +1 more source

Blood Biomarkers of Helicobacter pylori‐Infected Chronic Gastritis in Active Versus Stable Phases: A Clinical Indicator Analysis Combined With Proteomic and Metabolomic Investigations

iMetaMed, EarlyView.
Combining clinical data with serum proteomics and metabolomics, the HGB–CAPZB–acetic acid model was developed as a potential diagnostic index to distinguish the active and stable stages of Helicobacter pylori‐infected chronic gastritis, and the related mechanism was explored through multi‐omics.
Tiantong Jiang, Zhen Ma, Yang Li, Shaoli Wang, Yanjiao Zhang, Lei Song, Xianyu Li, Zhen Liu   +7 more
wiley   +1 more source

Nurse-Administered Sedation in Digestive Endoscopy: A Systematic Review

Diagnostics
Background/Objectives: Nurses are becoming increasingly common healthcare professionals who perform sedation in digestive endoscopy services. Efficacy, safety and patient satisfaction are indicators of quality and safety in the administration of sedation
Miriam Hidalgo-Cabanillas, José Alberto Laredo-Aguilera, Esperanza Barroso-Corroto, Ángel López-González, Joseba Rabanales-Sotos, Juan Manuel Carmona-Torres   +5 more
doaj   +1 more source

Parasitic Diseases of Upper Gastrointestinal Tract [PDF]

The Korean Journal of Helicobacter and Upper Gastrointestinal Research
Korea was a hotspot for parasitic infections until modern times. However, following economic development, improved health and hygiene and farming methods, and successful implementation of active deworming programs, human parasites are rare.
Heung Up Kim
doaj   +1 more source

Adss1–HDAC3 Interaction: A Novel Mechanism for Epigenetic Regulation of Metabolism in Adipose Tissue

iNew Medicine, EarlyView.
ABSTRACT Obesity and its related metabolic disorders have emerged as global public health challenges with underlying mechanisms involving an imbalance between energy storage and expenditure in the adipose tissue. In recent years, with the deepening research on adipose tissue metabolism, the cross talk between metabolic enzymes and epigenetic regulation
Jiarui Zhao, Jingjing Sun, Yan Lu, Ying Yang   +3 more
wiley   +1 more source

Deep learning‐assisted design of nanozyme for immune regulation

Journal of Intelligent Medicine, EarlyView.
Overview of nanozyme‐based strategies for inflammatory bowel disease therapy, featuring metal‐based and non‐metallic nanozymes classified by structure, alongside multifunctional and engineered probiotic‐based nanozymes classified by function. Abstract Inflammatory bowel disease (IBD), with rising global incidence and disease burden, is a multifactorial
Ke Chen, Si Sun, Shaofang Zhang, Huanhuan Qiao   +3 more
wiley   +1 more source