Results 111 to 120 of about 30,241 (215)

Sensing‐Integrated Patient‐Derived Tumorspheres Predict Chemotherapeutic Efficacy via Local Extracellular pH Dynamics

open access: yesSmall, EarlyView.
The study introduces a 3D sensing‐integrated platform enabling real‐time, non‐invasive monitoring of pH dynamics in patient‐derived PDAC tumorspheres. It revealed distinct extracellular acidification patterns under FOLFIRINOX, gemcitabine, and paclitaxel, correlating with therapeutic efficacy.
Stefania Forciniti   +10 more
wiley   +1 more source

Depth and Procedure Specific Effects of Antimicrobial Versus Conventional Sutures on Surgical Site Infection: A Systematic Review and Meta‐Analysis

open access: yesANZ Journal of Surgery, EarlyView.
Antimicrobial sutures may be particularly beneficial in colorectal and abdominal procedures, where reductions in deep SSI may offset the additional suture cost. Several studies also reported favorable wound‐healing outcomes. ABSTRACT Background Surgical site infections (SSIs) are common postoperative complications that delay wound healing and increase ...
Ryan Muakkassa   +3 more
wiley   +1 more source

Severe Abdominal Aortic Calcification in Pancreaticoduodenectomy: A Vascular Frailty Marker for Selecting Total Pancreatectomy?

open access: yesANZ Journal of Surgery, EarlyView.
Severe abdominal aortic calcification on preoperative CT may identify vascular frailty in patients undergoing pancreaticoduodenectomy. Integrated with fistula‐risk scores and frailty assessment, it may inform discussion of standard PD versus planned total pancreatectomy in selected high‐risk patients, while AAC alone is not an indication for TP ...
Mohamed Hajri   +3 more
wiley   +1 more source

Clinical Course and Predictors of Biologic Therapy, Hospitalisation and Surgery: A Five‐Year Prospective Study in Newly Diagnosed Inflammatory Bowel Disease

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
In this large multicentre Spanish inception cohort, biologics/JAK inhibitors were frequently used during the first 5 years after inflammatory bowel disease diagnosis and were associated with reduced hospitalisation risk, although not with lower abdominal surgery rates.
Ana Garre   +308 more
wiley   +1 more source

Successful endoscopic closure of a duodenal anastomotic leak using a through-the-scope suturing device. [PDF]

open access: yesEndoscopy
Marti Romero L   +4 more
europepmc   +1 more source

Review Article: Socioeconomic and Racial or Ethnic Inequalities Across the Colorectal Cancer Continuum: From Disparities to Action

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
Socioeconomic and racial or ethnic inequalities affect every stage of the colorectal cancer continuum, potentially worsening outcomes over time. The strongest evidence for reducing these inequalities is found in screening, which highlights the urgent need to develop and evaluate equity‐focused interventions in treatment, surveillance, and survivorship.
Marc Bardou   +3 more
wiley   +1 more source

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