Results 131 to 140 of about 45,270 (243)

Appropriate use of endoscopy in the diagnosis and treatment of gastrointestinal diseases: up-to-date indications for primary care providers

International Journal of General Medicine, 2010
Vien X Nguyen1, Vi Thuy Le Nguyen2, Cuong C Nguyen11Department of Gastroenterology, Mayo Clinic, Scottsdale, AZ, USA; 2Department of Pharmacy, Banner Baywood Medical Center, Mesa, AZ, USAAbstract: The field of endoscopy has revolutionized the diagnosis ...
Vien X Nguyen, Vi Thuy Le Nguyen, Cuong C Nguyen   +2 more
doaj  

Disordered Bile Acid Metabolism in Alcohol‐Related Hepatitis

Alimentary Pharmacology &Therapeutics, EarlyView.
Serum conjugated primary bile acids accumulate in alcohol‐related hepatitis due to downregulation of hepatocyte bile acid transporters. Hepatocyte growth factor is elevated in alcohol‐related hepatitis and downregulates BSEP expression. This detrimentally affects the hepatoprotective adaptive reduction in NTCP/increase in BSEP seen in cholestasis ...
Luke D. Tyson, Stephen Atkinson, Benjamin H. Mullish, Alexandros Pechlivanis, Michael Allison, Andrew Austin, Katie Chappell, Stuart J. Forbes, Ewan H. Forrest, Alastair M. Kilpatrick, Tong Liu, Laura Martinez‐Gili, Steven Masson, Mark J. W. McPhail, Joao Nunes, Paul Richardson, Daniel Rodrigo‐Torres, Stephen D. Ryder, Mark Wright, Vishal C. Patel, Nikhil Vergis, Elaine Holmes, Mark R. Thursz   +22 more
wiley   +1 more source

Correlation of Bile Acid Dynamics to Bulevirtide Response and Disease Severity in Patients With Hepatitis D

Alimentary Pharmacology &Therapeutics, EarlyView.
Bulevirtide increases bile acid levels in most patients; however, changes in bile acids do not predict virological response or adverse events, nor do they reflect treatment adherence. After discontinuation of bulevirtide, bile acid levels rapidly decline.
Marlene Hintersteininger, Michael Schwarz, Philipp Schwabl, Lukas Hartl, Lorenz Balcar, Benedikt Silvester Hofer, Georg Kramer, Christian Sebesta, Paul Thöne, Patrik Attalla, Michael Gschwantler, Michael Trauner, Mattias Mandorfer, Thomas Reiberger, Mathias Jachs   +14 more
wiley   +1 more source

The Emerging Short Chain Fatty Acid Enriched Metabotype in Irritable Bowel Syndrome and Its Potential Clinical Relevance

Alimentary Pharmacology &Therapeutics, EarlyView.
In a cohort of IBS‐D patients recruited to the TRITON study, faecal metabolomic profiling reveals a SCFA‐enriched metabotype associated with increased pain and urgency, altered stool characteristics and accelerated intestinal transit. ABSTRACT Background Metabolomic analysis in irritable bowel syndrome (IBS) has identified metabotypes enriched in ...
T. E. Conley, A. Duncan, A. Modasia, A. C. Ford, D. M. Pritchard, F. Hildebrand, F. J. Warren, R. Spiller, C. S. Probert   +8 more
wiley   +1 more source

Secular Trend in Glycaemic Management in Type 2 Diabetes Patients With and Without Cirrhosis Between 2000 and 2023: A Territory‐Wide Cohort Study

Alimentary Pharmacology &Therapeutics, EarlyView.
In this territory‐wide cohort study, improving glycemic control can be observed regardless of cirrhosis status. Oral antidiabetic medication was more often used in the non‐cirrhosis group, and insulin was preferred in patients with decompensated cirrhosis, who exhibited an increasing incidence of hypoglycemia over the years and need individualized ...
Mary Yue Wang, Sherlot Juan Song, Nana Peng, Grace Lai‐Hung Wong, Vincent Wai‐Sun Wong, Jimmy Che‐To Lai, Terry Cheuk‐Fung Yip   +6 more
wiley   +1 more source

Top 5 Advances in the Last 50 Years: Malignant Gastric and Esophageal Surgery

World Journal of Surgery, EarlyView.
Luís Santos Castro, Lorenzo Ferri
wiley   +1 more source

Relationships Between Job Engagement and Self‐Efficacy, Perceived Organisational Support and Perceived Job Security for Newly Recruited Nurses: A Cross‐Sectional Study

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aims To examine the relationships among perceived organisational support, perceived job security, self‐efficacy and job engagement among newly recruited nurses and the mediating role of perceived job security and self‐efficacy in the relationship between perceived organisational support and job engagement.
Rongfei Suo, Xiao'e Zeng, Liru Hao, Xiuping Ye, Haifeng Huang, Xiujun Fan, Zhen Ning, Yichun Zhang, Lidan Pang, Lihua Zhang, Xiaoha Lin, Song Zhou   +11 more
wiley   +1 more source

Five‐Year Unified Risk Prediction Model for Gastric and Esophageal Cancer Based on Nationwide Health Check‐Up Data in Japan: J‐GESS Score

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Background and Aim In Japan, gastric cancer (GC) and esophageal squamous cell carcinoma (ESCC) account for nearly all fatal upper gastrointestinal malignancies. A unified model that simultaneously predicts the incidence of these two cancers could help optimize endoscopic screening and postindex surveillance strategies.
Kenta Watanabe, Sho Fukuda, Dai Kubota, Nobutake Yamamichi, Yu Takahashi, Yoshitaka Watanabe, Kyoichi Adachi, Norihisa Ishimura, Tomoyuki Koike, Hideyuki Sugawara, Kiyotaka Asanuma, Yasuhiko Abe, Takashi Kon, Eikichi Ihara, Kazuhiro Haraguchi, Yoshihiro Otsuka, Rie Yoshimura, Yugo Iwaya, Takuma Okamura, Noriaki Manabe, Akira Horiuchi, Mio Matsumoto, Kengo Onochi, So Takahashi, Tatsuki Yoshida, Yosuke Shimodaira, Katsunori Iijima   +26 more
wiley   +1 more source

Dietary management of normoalbuminaemic canine chronic enteropathies

Journal of Small Animal Practice, EarlyView.
Dietary management represents the cornerstone of treatment for chronic enteropathy in dogs, with approximately 50% of cases in referral practice responding to dietary intervention alone. Success rates improve significantly when multiple systematic diet trials are implemented.
A. Kathrani, K. Allenspach, D. Dito, J. Hernandez, S. Unterer, M. Vecchio, C. Webb, M. K. Tolbert   +7 more
wiley   +1 more source

Length of the Adult Human Colon in Health and Constipation Measured Using Magnetic Resonance Imaging

Neurogastroenterology &Motility, EarlyView.
Colon length was measured in adult healthy volunteers, people with chronic constipation, and people with IBS with constipation using MRI. Colon length is significantly longer in chronic constipation. The chronically constipated colon is unable to accommodate longitudinally in response to fluid influx from a macrogol challenge.
Faiz Alqarni, Soma Kumasaka, Caroline L. Hoad, Victoria Wilkinson‐Smith, Stuart Taylor, David Atkinson, Iyad Naim, Alex Menys, S. Mark Scott, Marc A. Benninga, Hayfa Sharif, Penny A. Gowland, Moira A. Taylor, Guruprasad P. Aithal, Robin C. Spiller, Maura Corsetti, Luca Marciani   +16 more
wiley   +1 more source