Reprogramming the gastrointestinal microenvironment with intelligent biomaterials and digital medicine: a perspective on precision intervention for digestive diseases. [PDF]
Peng L, Jia X, Chen H, Wang Y, Du X.
europepmc +1 more source
ABSTRACT Objectives Studies of non‐anesthesiologist‐administered propofol (NAAP) during colorectal endoscopic submucosal dissection (ESD) are scarce, particularly in the elderly. We evaluated its feasibility across a broad age range and identified factors associated with sedation‐related adverse events.
Yumi Kishi +16 more
wiley +1 more source
Endoscopic ultrasound-guided radiofrequency ablation in the treatment of pancreatic ductal adenocarcinoma: when science tries to increases hope. [PDF]
Ardengh JC, Kemp R, Santos JSD.
europepmc +1 more source
Evaluation of Mutation Risk Using Patient‐Derived Organoids in Patients With Lynch Syndrome
ABSTRACT Lynch syndrome (LS) is a hereditary cancer predisposition syndrome caused by germline mutation of DNA mismatch repair (MMR) genes, most notably associated with colorectal cancer. Although LS patients face high risk of CRC, risk can vary even among those with the same pathogenic MMR germline mutations. We suggest a functional assay platform for
Youmi Shin +10 more
wiley +1 more source
The Impact of Artificial Intelligence-Assisted Endoscopy on the Detection of Upper Gastrointestinal Neoplasms: A Systematic Review and Meta-Analyses. [PDF]
Liu M +5 more
europepmc +1 more source
ABSTRACT Background Patients with recurrent head and neck cancer (HNC) often present with severe, persistent dysphagia and xerostomia following prior chemoradiation. Although swallowing impairments and salivary dysfunction have been reported in this population, prior longitudinal studies have not examined changes in salivary composition or how these ...
Jenni Wu +8 more
wiley +1 more source
How Does Artificial Intelligence-Assisted Endoscopy Impact Upper Gastrointestinal Screening? [PDF]
Suzuki S.
europepmc +1 more source
ABSTRACT Background Despite an expanding repertoire of advanced therapies for inflammatory bowel disease (IBD), treatment outcomes remain suboptimal, with only 30%–40% of patients achieving sustained remission. Emerging evidence indicates that therapeutic outcomes are shaped by complex interactions between host immune pathways, the gut microbiome and ...
John P. Thomas +14 more
wiley +1 more source
Intravascular Large B-Cell Lymphoma Diagnosed on Gastroesophageal Junction Biopsy During Evaluation of Dysphagia. [PDF]
Bandaranaike R +3 more
europepmc +1 more source
A prospective study of 150 outpatients with moderate‐to‐severe UC initiating treatment. IUS is performed at baseline, day‐2, ‐7, ‐90 and week 52 alongside clinical, biochemical, endoscopic, patient‐reported and exploratory multiomics assessments. The primary endpoint evaluates whether early change in BWT predicts treatment escalation within 3 and 12 ...
Sabrina Josefsen +6 more
wiley +1 more source

