Results 171 to 180 of about 30,241 (215)

Migration‐Associated Variation in Gastric Cancer Risk in the United States: Implications for Risk Stratification

open access: yesInternational Journal of Cancer, Volume 159, Issue 8, Page 1891-1903, 15 October 2026.
This study provides contemporary, population‐based evidence that migration‐associated differences in gastric cancer risk, first described decades ago, remain stable, quantifiable, and prevention‐relevant in the United States. By integrating modern cancer registry data with formal trend analysis and conditional extrapolation, the authors show that ...
Chul S. Hyun   +4 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, Volume 600, Issue 19, Page 2876-2898, October 2026.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Probiotic‐Derived Vesicles Rectally Delivered via Thermo‐Gelling Copolymer Promote Mucosal Healing and Reduce Inflammation in Ulcerative Colitis

open access: yesAdvanced Science, Volume 13, Issue 56, 9 October 2026.
A thermo‐responsive rectal delivery platform integrating probiotic‐derived extracellular vesicles within a hyaluronic acid‐based copolymer enables localized and sustained therapy for ulcerative colitis. The formulation effectively suppresses inflammation, promotes macrophage polarization toward a regenerative phenotype, restores epithelial barrier ...
Ayushi Mairal   +5 more
wiley   +1 more source

Programming Gut Microbiome Function Through Cross‐Feeding: From Ecological Mechanisms to Live Biotherapeutics

open access: yesAdvanced Science, Volume 13, Issue 55, 5 October 2026.
This graphical abstract presents gut microbial cross‐feeding through a Mechanism–Technology–Application framework. It summarizes major resource‐transfer modes, the experimental and computational tools used to establish causality, and potential interventions involving dietary substrates, live biotherapeutic products, and engineered microbes.
Chuankai Sun   +7 more
wiley   +1 more source

Serum Bile Acid Metabolomics‐Based Machine Learning Model for Non‐Invasive Diagnosis of Gastric Cancer

open access: yesCancer Medicine, Volume 15, Issue 10, October 2026.
ABSTRACT Background Gastric cancer (GC) has posed a severe threat to human health. Metabolomics analysis has been applied in the context of multiple diseases, offering new perspectives for the development of non‐invasive detections. Objective We aimed to develop a diagnostic model for GC based on a serum bile acid (BA) panel.
Nuo Yao   +10 more
wiley   +1 more source

ISG Task Force on Upper Gastrointestinal Bleeding (UGIB)—Comparison of Risk Scores in Nonvariceal Bleeding—A Prospective Multicenter Study [PDF]

open access: yesJGH Open
ABSTRACT Background To compare the performance of the Glasgow Blatchford score (GBS) to the Total Rockall score (TRS) in predicting clinical interventions in Indian patients with acute nonvariceal upper gastrointestinal bleeding (ANVUGIB). Materials and Methods We prospectively studied ANVUGIB in 93 hospitals in India from October 2014 to September ...
Sahu M   +36 more
europepmc   +2 more sources

Gastric Emptying in Obesity and Weight‐Loss Interventions: Physiology, Assessment, and Clinical Implications

open access: yesComprehensive Physiology, Volume 16, Issue 5, October 2026.
Obesity is associated with accelerated gastric emptying. Weight‐loss interventions each impose a distinct emptying signature: acceleration after sleeve gastrectomy and gastric bypass, delay after endoscopic sleeve gastroplasty, intragastric balloon, and GLP‐1 receptor agonists.
Maxime Amoyel   +4 more
wiley   +1 more source

Gallstone formation and hepatobiliary tumour risk: Clinical implications of the bile acid–gut microbiota axis

open access: yesClinical and Translational Discovery, Volume 6, Issue 5, October 2026.
1. Irregular dietary patterns (e.g., late breakfast, reduced meal frequency) upregulate the bai gene cluster by disrupting cholecystokinin (CCK) release rhythms and gut microbiota circadian rhythms, leading to increased production of secondary bile acids, particularly DCA. High‐carbohydrate dietary patterns increase gallstone risk (OR = 1.329).
Rui Li   +6 more
wiley   +1 more source

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