Results 181 to 190 of about 45,270 (243)

Effect of Mirikizumab on Clinical and Endoscopic Outcomes Based on Prior Advanced Therapy Failure in Patients With Moderately to Severely Active Ulcerative Colitis

United European Gastroenterology Journal, Volume 14, Issue 4, May 2026.
ABSTRACT Background Mirikizumab demonstrated efficacy in moderately‐to‐severely active ulcerative colitis, including in patients with prior advanced therapy failure (PATF) (Phase 3: LUCENT‐1 [NCT03518086], LUCENT‐2 [NCT03524092]). This post hoc analysis evaluates mirikizumab efficacy by number/mechanism of PATF.
Ailsa Hart, Seyedehsan Navabi, Geert D'Haens, Katsuyoshi Matsuoka, María Dolores Martín‐Arranz, Raja Atreya, Karen Hamrick Samaan, Endip Dhesi, Isabel Redondo, Baojin Zhu, Jerome Paulissen, Liliana Zaremba‐Pechmann, Simin Baygani, Jimmy Limdi, David Laharie, Silvio Danese   +15 more
wiley   +1 more source

Ondasetron as Premedication for Unsedated Upper Digestive Endoscopy: A Cross-Sectional Study Assessing Tolerance and Acceptability. [PDF]

Health Sci Rep
Murhi EB, Iranga RB, Lembembu C, Shindano TA.   +3 more
europepmc   +1 more source

Spontaneous resolution of a gastro‐gastric intussusception in a dog: Diagnostic approach and clinical implications

Veterinary Record Case Reports, Volume 14, Issue 2, May 2026.
Abstract A 7‐month‐old, male, entire Dalmatian dog presented with acute‐onset haematemesis. Following symptomatic medical treatment, vomiting resolved, although the dog remained subdued and inappetent. True gastro‐gastric intussusception was suspected on abdominal radiography and ultrasonography and was confirmed by contrast‐enhanced computed ...
Afroditi Evangelia Pontikaki, Henry Cloete, Anthi Katsiorchi, William J. E. Humphreys, Rachel Burrow   +4 more
wiley   +1 more source

Combined gastric mucosal ablation of the fundus using a new hybrid device with endoscopic sleeve gastroplasty for obesity. [PDF]

Endoscopy
Boškoski I, Gualtieri L, De Siena M, Matteo MV, Pontecorvi V, Spada C, Bove V.   +6 more
europepmc   +1 more source

Acetylcholine From Solitary Chemosensory Cell, Not Neuron, Regulates Basal Cell Fate Driving Eosinophilic Chronic Rhinosinusitis With Nasal Polyps

Allergy, Volume 81, Issue 5, Page 1617-1634, May 2026.
This study identifies that Ach levels are elevated in eCRSwNP and primarily released from SCCs rather than neurons. Ach induces epithelial remodeling in eCRSwNP by binding to M1R/M3R and activating YAP signaling in basal cells, driving basal cell hyperplasia and abnormal differentiation. Blocking M1R/M3R with TB inhibits eCRSwNP progression.
Bowen Zheng, Tao Lu, Ji Wang, Yalan Zhang, Panhui Xiong, Jieyu Zeng, Shuman Li, Yu Jiang, Yijun Liu, Longlan Shu, Yuan Chen, Yin Zhou, Yue Gu, Dayu Guan, Chenxi Li, Lei Zhao, Shujin Wang, Jie Liu, Xia Ke, Yang Shen, Yucheng Yang   +20 more
wiley   +1 more source

Club Cells in Nasal Epithelial Repair: Insights From an IL‐13‐Induced Inflammatory Model

Allergy, Volume 81, Issue 5, Page 1459-1471, May 2026.
Four inflammatory endotypes of CRSwNP, defined by eosinophil and neutrophil infiltration, show distinct patterns of basal, club, ciliated, and goblet cell expression in nasal epithelium. Using an ALI‐HNECs model, we demonstrate that IL‐13 impairs mucociliary function by promoting club‐to‐goblet cell differentiation while inhibiting club‐to‐ciliated ...
Zhi‐Qun Huang, Jing Liu, Jing Ye, Li‐Ying Sun, Hsiao Hui Ong, Yang Peng, Bing‐Qi Lin, Jun‐Hao Tu, Ke‐Shuang Wang, Yi‐Shan Xiong, Qing Luo, Mark Thong, Yu Xu, De‐Yun Wang   +13 more
wiley   +1 more source

School and School‐Related Experiences of Children and Adolescents With Inflammatory Bowel Disease: A Scoping Review

Child: Care, Health and Development, Volume 52, Issue 3, May 2026.
ABSTRACT Background This scoping review explores the school and school‐related experiences of children and adolescents with Inflammatory Bowel Disease (IBD), drawing on 10 studies identified from an initial pool of 2676 records published between 2014 and 2022 across eight countries. The review identifies the following four key themes: school attendance/
Jenna Rice, Catherine Wilkinson
wiley   +1 more source

Endoscopist and Patients' Values and Preferences on Artificial Intelligence in Endoscopy: An Intercontinental Opinion Survey by the World Endoscopy Organization. [PDF]

Dig Endosc
Ahmad OF, de Groof A, Ali A, Bassett P, Engels M, Hoogenboom S, Coelho-Prabhu N, Yu H, Mwachiro M, Parasa S, Vivar RM, Mushtaq J, Neumann H, Thakkar S, Byrne MF, van Hooft JE, Yano T, Mori Y.   +17 more
europepmc   +1 more source

Case Report: Scar-Like Alterations of the Gastric Mucosa Observed Under Endoscopy in Collagenous Gastritis. [PDF]

Clin Case Rep
Luo Q, Li Y, Liu J, Lin X, Zhou S.
europepmc   +1 more source

Collagen and microvascular alterations contribute to neuromuscular degeneration and disease progression in chronic intestinal pseudo‐obstruction

Journal of Internal Medicine, Volume 299, Issue 5, Page 587-603, May 2026.
Abstract Background Chronic intestinal pseudo‐obstruction (CIPO) is a severe gastrointestinal motility disorder that may be idiopathic or associated with systemic disease. In idiopathic cases, the pathophysiological mechanisms remain poorly defined. Although mutations in angiogenic factors have been reported in mitochondrial forms of CIPO, their role ...
Elisa Boschetti, Irene Neri, Leonardo Caporali, Elena Bonora, Carolina Malagelada, Claudio Fiorini, Danara Ormanbekova, Alessandro Berghella, Roberto D'Angelo, Rita Rinaldi, Cristiana Caliceti, Anna Costanzini, Mirella Falconi, Vincenzo Stanghellini, Stefano Ratti, Lucia Manzoli, Valerio Carelli, Roberto De Giorgio   +17 more
wiley   +1 more source