Results 41 to 50 of about 29,303 (219)

Direct cholangioscopy for recurrent pancreatitis after choledochal cyst surgery: Its role in diagnosis and surveillance

International Journal of Gastrointestinal Intervention
We report the case of a 20-year-old woman with a complex type “D” pancreaticobiliary maljunction and recurrent pancreatitis who underwent surgical resection with Roux-en-Y reconstruction. Fourteen years later, magnetic resonance cholangiopancreatography (
Mario Brusco, Simona Faraci, Paola De Angelis, Valerio Balassone   +3 more
doaj   +1 more source

Endoscopic mucosal resection of flat and sessile colorectal adenomas: Our experience with long-term follow-ups [PDF]

Vojnosanitetski Pregled, 2014
Bacground/Aim. Endoscopic mucosal resection (EMR) or mucosectomy is a removing method of flat or sessile lesions, laterally spreading tumors and carcinoma of the colon or the rectum limited to mucosa or the surface part of the submucosa. The aim
Grgov Saša, Dugalić Predrag, Tomašević Ratko, Tasić Tomislav   +3 more
doaj   +1 more source

Senkyunolide I Inhibits mtDNA‐cGAS‐STING Signaling in Macrophages via Targeting VDAC1 Oligomerization to Attenuate Ulcerative Colitis

Advanced Science, EarlyView.
In macrophages, senkyunolide I (SEI) directly targets the K12 residue of VDAC1 to inhibit its stress‐induced oligomerization, a critical upstream event that effectively prevents mitochondrial DNA release and subsequent cGAS‐STING pathway activation.
Zhiming Ye, Yihang Huang, Bohao Han, Lei Zhang, Can Yu, Yang Yang, Bing Liu, Yongping Jian, Zhixiang Xu, Cheng Zeng   +9 more
wiley   +1 more source

Endoscopic diagnosis and treatment of neuroendocrine tumors of the digestive system

Open Medicine, 2016
The authors evaluated the role of endoscopic techniques in the diagnosis and in the potential treatment of neuroendocrine tumors (NET) localized in the gastro-entero-pancreatic system, on the basis of their experience and of the international literature.
Sivero Luigi, Telesca Donato Alessandro, Ruggiero Simona, Russo Teresa, Amato Maurizio, Bianco Tommaso, Amato Bruno, Formisano Cesare, Avellino Manuela, Napolitano Vincenzo   +9 more
doaj   +1 more source

Iron‐Tannic Acid Hydrogel Mediated Mild Photothermal Therapy Combined With Ferroptosis Enhances Anti‐Tumor Immunity in Colorectal Cancer

Advanced Science, EarlyView.
An injectable gelatin‐based tannic acid–iron hydrogel with mild photothermal therapy could not only induce immunogenic cell death, but also elicit ferroptosis of both tumor cells and tumor‐associated macrophages, resulting in DC maturation, T‐cell infiltration and down‐regulation of ferroptosis‐sensitive M2‐type TAMs levels.
Yuan Zhu, Xi Yu, Tao Wang, Wanyi Liu, Chang Lu, Jiani Zhong, Yujie He, Wei Li, Kunxi Zhang, Peihao Yin, Zeting Yuan   +10 more
wiley   +1 more source

Programming Gut Microbiome Function Through Cross‐Feeding: From Ecological Mechanisms to Live Biotherapeutics

Advanced Science, EarlyView.
This graphical abstract presents gut microbial cross‐feeding through a Mechanism–Technology–Application framework. It summarizes major resource‐transfer modes, the experimental and computational tools used to establish causality, and potential interventions involving dietary substrates, live biotherapeutic products, and engineered microbes.
Chuankai Sun, Teng Ma, Hao Jin, Zelong Li, Yi Cheng, Jingjin Li, Lai‐Yu Kwok, Zhihong Sun   +7 more
wiley   +1 more source

Exploration of the optimal regimen of gastric mucosal cleansing medication for the H. pylori population before ME-NBI screening: study protocol for a single-center, single-blind, randomized controlled trial

Frontiers in Medicine
ObjectiveMagnifying endoscopy combined with narrow-band imaging endoscopy is an emerging method for early gastric cancer screening and diagnosis However, its effectiveness is closely related to the cleaning quality of the gastric mucosal preparation.
Xinyi Mu, Yi Fan, Jingyu Xu, Rui Xie
doaj   +1 more source

Diagnostic Accuracy of Size‐Based Preoperative CT Assessment for Predicting Lymph Node Metastasis in Colon Cancer: A Systematic Review and Meta‐Analysis

Annals of Gastroenterological Surgery, EarlyView.
Preoperative CT based on lymph node size shows moderate accuracy for detecting nodal metastasis in colon cancer. In this meta‐analysis of 29 studies (5,634 patients), pooled sensitivity and specificity were 0.69 and 0.66. Size‐based CT alone has limited value for clinical decision‐making.
Yuji Takayama, Tomoya Shimizu, Jun Watanabe, Shimpei Ogawa, Yukihide Kanemitsu   +4 more
wiley   +1 more source

The application of gastrointestinal endoscopy in children: a narrative review

Frontiers in Pediatrics
Digestive endoscopy in children is increasingly used for the diagnosis and treatment of a broad range of diseases affecting the stomach, intestines, biliary tract, and pancreas, with the advantages of being minimally invasive and efficient.
Guo Zhang, Guiping Zhao, Peng Li, Shutian Zhang   +3 more
doaj   +1 more source

MiR‐146a‐5p Suppresses M1 Polarization of Tumor‐Associated Macrophages via IRAK1/NF‐κB Signaling in Colorectal Polyps

Annals of Gastroenterological Surgery, EarlyView.
MiR‐146a‐5p is downregulated in colorectal polyps, leading to IRAK1 upregulation and NF‐κB activation, which promotes M1 macrophage polarization and inflammation. Overexpression of miR‐146a‐5p suppresses IRAK1/NF‐κB signaling, reduces M1 polarization, and alleviates inflammatory responses.
Peng Song, Lianhui Wu, Huabin Qiu, Lei Luo, Jianzhao Qiu, Shuping Xiao, Jincai He   +6 more
wiley   +1 more source