Results 311 to 320 of about 537,635 (384)
Mechanism of Lenvatinib Resistance via Exosomal miRNA‐132/Nrf2 Axis in Hepatocellular Carcinoma
Exosomal miRNA‐132 from LVT‐res HCC cells activated Nrf2 expression through the PTEN/GSK3β pathway in recipient cells. This cascade could induce drug resistance in non‐resistant HCC cells in the TME. ABSTRACT Introduction Lenvatinib is a multiple receptor tyrosine kinase inhibitor and a first‐line targeted therapy for hepatocellular carcinoma (HCC ...
Chie Takasu +7 more
wiley +1 more source
A novel slim cholangioscope facilitates antegrade laser lithotripsy for an intrahepatic biliary stone with acute ductal angulation. [PDF]
Miwa H +6 more
europepmc +1 more source
This study showed that the pancreaticogastrostomy technique in HPD of biliary tract cancer reduced the incidence of pancreatic fistula from 45% to 12%. In‐hospital mortality was also reduced from 27% to 3%. ABSTRACT Background and Purpose Although hepatopancreaticoduodenectomy (HPD) is effective for margin‐negative curative resection of biliary tract ...
Ryusei Matsuyama +9 more
wiley +1 more source
Salvage hemostasis with endoscopic suturing for refractory transverse colonic ulcer bleeding. [PDF]
Wu TL, Su PY, Chen YY, Yen HH.
europepmc +1 more source
This prospective study investigated the impact of MIS on frailty and outcomes in elderly CRC patients. While frail patients showed lower OS, MIS was safely performed. Among recurrence‐free patients, frailty status improved at 1 year, suggesting that curative surgery may offer not only oncologic benefits but also potential for frailty improvement ...
Hajime Ushigome +9 more
wiley +1 more source
Multiple transluminal gateway technique for drainage of an infected walled-off pancreatic necrosis and pancreatic pseudocyst. [PDF]
Altonbary A +3 more
europepmc +1 more source
ABSTRACT Background Large type III gastric cancer (GC) ≥ 8 cm has conventionally been categorized with type IV GC in Japan, leading to alternative treatment strategies such as neoadjuvant chemotherapy and staging laparoscopy (SL). However, whether 8 cm is the correct cutoff remains unclear.
Yutaka Sugita +8 more
wiley +1 more source

