Results 51 to 60 of about 288,270 (313)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Gastric Peroral Endoscopic Myotomy (G-POEM) as a Treatment for Refractory Gastroparesis: Long-Term Outcomes

open access: yesCanadian Journal of Gastroenterology and Hepatology, 2018
Background and Aims. Gastric peroral endoscopic myotomy (G-POEM) has been regarded as a novel and minimally invasive therapy for refractory gastroparesis.
Jiaxin Xu   +9 more
doaj   +1 more source

Endoscopy in surgery

open access: yesTurkish Journal of Surgery, 2021
In the last 20 years, there have been important developments in endoscopy. Initially, endoscopy was developed and used as a diagnostic tool. As new technology developed, these devices also became the basis for therapeutic maneuvers. In recent years, flexible endoscopes have been used to per- form procedures replacing traditional surgical approaches ...
Ahmet Serdar, Karaca   +3 more
openaire   +3 more sources

Should Capsule Endoscopy Be the First Test for Every Obscure Gastrointestinal Bleeding?

open access: yes, 2019
Obscure gastrointestinal bleeding (OGIB) refers to gastrointestinal (GI) bleeding of unclear origin that persists or recurs after negative findings on esophagogastroduodenoscopy and colonoscopy.
태정현, 심기남
core   +1 more source

Nomenclature and definition of atrophic lesions in small bowel capsule endoscopy : a Delphi consensus statement of the International CApsule endoscopy REsearch (I-CARE) Group [PDF]

open access: yes, 2022
(1) Background: Villous atrophy is an indication for small bowel capsule endoscopy (SBCE). However, SBCE findings are not described uniformly and atrophic features are sometimes not recognized; (2) Methods: The Delphi technique was employed to reach ...
Rami Eliakim   +155 more
core   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Esophageal submucosal tumor diagnosed with EBUS‐guided transbronchial mediastinal cryobiopsy: A case report

open access: yesThoracic Cancer, 2022
Cryobiopsy is advantageous for collecting larger specimens with minimum crushing compared to forceps biopsy and transbronchial needle aspiration (TBNA), but it has not been widely used for mediastinal tumors.
Yuki Ishiguro   +6 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Endoscopic Management of Jejunal Diverticular Bleeding: A Case Report and Systematic Review of the Literature

open access: yesCase Reports in Gastrointestinal Medicine
Bleeding from a jejunal diverticulum is a rare and potentially severe condition, challenging both to diagnose and to treat. We report the case of a 56-year-old woman presenting with massive melena, who initially underwent esophagogastroduodenoscopy (EGD)
Marta Pettinelli   +7 more
doaj   +1 more source

The evolution of lower gastrointestinal endoscopy; where are we now [PDF]

open access: yes, 2020
Lower gastrointestinal (LGI) endoscopy has evolved over time fulfilling a widening diagnostic and therapeutic remit. As our understanding of colorectal cancer and its prevention has improved, endoscopy has progressed with improved diagnostic technologies
Patel, Kinesh   +5 more
core   +1 more source

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