Results 31 to 40 of about 5,412,359 (296)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Accuracy of UWB Path Loss-Based Localization of Wireless Capsule Endoscopy

Journal of Healthcare Engineering, 2023
Wireless capsule endoscopy (WCE) is used to diagnose lesions in the gastrointestinal (GI) tract. The physicians require to know the exact position of the lesions which can be performed by localizing the WCE in the GI tract.
Umma Hany, L. Akter
semanticscholar   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Patient-derived measures of GI endoscopy: a meta-narrative review of the literature

, 2015
Background and AimsGI endoscopy (GIE) is widely performed, with 1 in 3 people requiring an endoscopic procedure at some point. Patient experience of medical procedures is important, but, to date, experience measures of GIE are derived from clinician ...
Rubin, Greg, Nixon, Catherine, Rees, Colin, Rees, Colin J, Brown, Sally, Dunn, Simon, Bevan, Roisin, Panter, Simon   +7 more
core   +1 more source

Safety of Prescription Nonsteroidal Anti‐inflammatory Drugs in Adults With Inflammatory Bowel Disease: Data From a Large Administrative Claims Cohort

Arthritis Care &Research, EarlyView.
Objective The concern that nonsteroidal anti‐inflammatory drugs (NSAIDs) may precipitate flares of inflammatory bowel disease (IBD) has limited their use in managing musculoskeletal symptoms in those with IBD, but safety data are mixed. Methods This retrospective cohort study included patients with IBD aged at least 18 years from Optum's deidentified ...
Adam S. Mayer, Rui Xiao, Meenakshi Bewtra, Michael D. George, Pamela F. Weiss   +4 more
wiley   +1 more source

Video Capsule Endoscopy: Think Pharyngeal Pouch – Retention of a Video Capsule in a 94-Year-Old in the Upper Gastrointestinal Tract

Annals of Geriatric Medicine and Research
Video capsule endoscopy (VCE) provides endoluminal visualisation of the small bowel. It is often regarded as well-tolerated, non-invasive, and safe across all age groups, with the main, albeit rare, complication of retention of the capsule, normally in ...
William Tai, R. Claassen
semanticscholar   +1 more source

Severe lower respiratory tract infection in early infancy and pneumonia hospitalizations among children, Kenya. [PDF]

, 2013
Severe lower respiratory tract infection (LRTI) in infants caused by respiratory syncytial virus (RSV) has been associated with later pneumonia hospitalization among children.
Eric O. Ohuma, Nokes, D. James, Nokes, DJ, Ngama, Mwanajuma, Ngama, M, Patrick Kiio Munywoki, Bauni, E, Scott, J Anthony G, Ohuma, Eric O., Munywoki, Patrick Kiio, Scott, John, Ohuma, EO, J. Anthony G. Scott, Munywoki, PK, Bauni, Evasius, Mwanajuma Ngama, Scott, J. Anthony G., Nokes, D James, Ohuma, Eric O, Evasius Bauni, D. James Nokes   +20 more
core   +1 more source

Programmable Pneumatic Actuator System for a Bioinspired Artificial Colon

Advanced Materials Technologies, EarlyView.
A modular soft robotic colon simulator driven by programmable pneumatic actuation is developed to mimic physiological and pathological‐like motility patterns of the large intestine. Finite element–guided design and distributed control enable anatomically realistic deformation for peristalsis, segmentation, and mass movements, supporting capsule ...
Andrew Bickerdike, Bo Tian, Xizheng Fang, Zepeng Wang, Yang Liu, Lucy Adams, Shyam Prasad   +6 more
wiley   +1 more source

Gastrointestinal cancer screening and surveillance programmes : a worldwide perspective : part 1 [PDF]

, 2012
Part 2 of this article can be found through this link: https://www.um.edu.mt/library/oar//handle/123456789/13101Cancer is a leading cause of death worldwide and such deaths are projected to continue to rise, creating significant morbidity and ...
Gerada, Jurgen
core