Results 91 to 100 of about 585,558 (296)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Enhanced endothelial cell density on NiTi surfaces with sub-micron to nanometer roughness

International Journal of Nanomedicine, 2008
Harry D Samaroo, Jing Lu, Thomas J WebsterDivision of Engineering, Brown, University, Providence, RI, USAAbstract: The shape memory effect and superelastic properties of NiTi (or Nitinol, a nickel-titanium alloy) have already attracted much attention for
Harry D Samaroo, Jing Lu, Thomas J Webster   +2 more
doaj  

Longitudinal Changes to Tight Junction Expression and Endothelial Cell Integrity in a Mouse Model of Sterile Corneal Inflammation [PDF]

, 2016
PURPOSE: We previously reported that applying toll-like receptor (TLR) ligands to an injured cornea induces corneal edema at 24 hours, which subsides by 1 week.
Larkin, DFP
core   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Millennial Generation’s Choice of Contact Lens as the Preference Over Spectacles: A Study of Corneal Endothelial Cell Density

Medical Journal of Dr. D.Y. Patil Vidyapeeth
Introduction: The cornea of the eye is the most vulnerable organ to external insult. Contact lens is no exception. Changes in corneal epithelium, stroma, and loss of hexagonal shape in the endothelium have been taught in contact lens classes.
Neeta Mishra, Neelam Prasad, Rekha Chotalia, Uday Bajare, Veshal V. Madan   +4 more
doaj   +1 more source

Morphological Changes of Human Corneal Endothelial Cells after Rho-Associated Kinase Inhibitor Eye Drop (Ripasudil) Administration: A Prospective Open-Label Clinical Study.

PLoS ONE, 2015
PurposeTo investigate the effect and safety of a selective Rho kinase inhibitor, ripasudil 0.4% eye drops, on corneal endothelial cells of healthy subjects.DesignProspective, interventional case series.MethodsIn this study, 6 healthy subjects were ...
Hiroko Nakagawa, Noriko Koizumi, Naoki Okumura, Hideki Suganami, Shigeru Kinoshita   +4 more
doaj   +1 more source

The relationship between oxidised LDL, endothelial progenitor cells and coronary endothelial function in patients with CHD [PDF]

, 2016
Objective The balance between coronary endothelial dysfunction and repair is influenced by many protective and deleterious factors circulating in the blood.
Ahmed, Nadeem, Berry, Colin, Hayhurst, James, Kennedy, Simon, McClure, John D., Oldroyd, Keith G., Wadsworth, Roger M., Watt, Jonathan   +7 more
core   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Association of corneal endothelial cell morphology with neurodegeneration in mild cognitive impairment and dementia

Alzheimer’s & Dementia: Translational Research & Clinical Interventions
INTRODUCTION Corneal confocal microscopy (CCM) detects neurodegeneration in mild cognitive impairment (MCI) and dementia and identifies subjects with MCI who develop dementia.
Georgios Ponirakis, Hanadi Al Hamad, Alaa S. Al‐Waisy, Ioannis N. Petropoulos, Adnan Khan, Hoda Gad, Mani Chandran, Masharig Gadelseed, Salah Mahmoud, Ahmed Elsotouhy, Marwan Ramadan, Shafi Khan, Rustu E. Akcan, Priya V. Gawhale, Noushad Thodi, Tala Nakouzi, Moayad Homssi, Nebras Hadid, Aisha Al Obaidan, Rawan Hussein, Ahmed Own, Ashfaq Shuaib, Rayaz A. Malik   +22 more
doaj   +1 more source

CORNEAL ENDOTHELIOPATHY IN PSEUDOEXFOLIATION SYNDROME

The Iraqi Journal of Medical Sciences, 2018
Background: Pseudoexfoliation syndrome is a common disorder with a wide range of ophthalmic presentation and risks. Corneal endotheliopathy is one of these presentations. Objective: To evaluate corneal endothelial cell morphology, density and function in
Alyaà Kareem, Giyath Aldeen Neamah
doaj   +1 more source