Results 101 to 110 of about 7,772,950 (251)

Predictive Value of Composite Inflammatory Markers for Stroke Prognosis: A Prospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Novel composite inflammatory markers' role in stroke prognosis is understudied, and the best predictor is unclear, requiring further exploration. Objectives This study aimed to systematically evaluate the associations of 6 novel composite inflammatory markers on stroke prognosis.
Bing Wu, Jie‐Jie Li, Jing Jing, Jin‐Xi Lin, Xia Meng, Yong Jiang, Yong‐Jun Wang, Hong‐Qiu Gu   +7 more
wiley   +1 more source

Morphological Changes of Human Corneal Endothelial Cells after Rho-Associated Kinase Inhibitor Eye Drop (Ripasudil) Administration: A Prospective Open-Label Clinical Study.

PLoS ONE, 2015
PurposeTo investigate the effect and safety of a selective Rho kinase inhibitor, ripasudil 0.4% eye drops, on corneal endothelial cells of healthy subjects.DesignProspective, interventional case series.MethodsIn this study, 6 healthy subjects were ...
Hiroko Nakagawa, Noriko Koizumi, Naoki Okumura, Hideki Suganami, Shigeru Kinoshita   +4 more
doaj   +1 more source

CORNEAL ENDOTHELIOPATHY IN PSEUDOEXFOLIATION SYNDROME

The Iraqi Journal of Medical Sciences, 2018
Background: Pseudoexfoliation syndrome is a common disorder with a wide range of ophthalmic presentation and risks. Corneal endotheliopathy is one of these presentations. Objective: To evaluate corneal endothelial cell morphology, density and function in
Alyaà Kareem, Giyath Aldeen Neamah
doaj   +1 more source

Prostaglandin E Positively Modulates Endothelial Progenitor Cell Homeostasis: An Advanced Treatment Modality for Autologous Cell Therapy [PDF]

, 2009
Aims: The mobilization of endothelial progenitor cells (EPC) and their functioning in postnatal neovascularization are tightly regulated. To identify new modulators of EPC homeostasis, we screened biologically active prostaglandin E compounds for their ...
Hermann, Patrick C., Schwarz, Theresa M., Kopp, Reinhard, Huber, Stephan, Heeschen, Christopher, Herrler, Tanja, Leicht, Simon F.   +6 more
core   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source

Endothelial cell pseudopods and angiogenesis of breast cancer tumors

Cancer Cell International, 2005
Background A neoplastic tumor cannot grow beyond a millimeter or so in diameter without recruitment of endothelial cells and new blood vessels to supply nutrition and oxygen for tumor cell survival. This study was designed to investigate formation of new
Sun LuZhe, Short Nicholas, Cameron Ivan L, Hardman W Elaine   +3 more
doaj   +1 more source

Semaphorins guide PerPlexeD endothelial cells

, 2004
Abrogation of the endothelial cell-specific semaphorin receptor PlexinD1 in zebrafish and mouse reveals semaphorin functions selectively affecting the cardiovascular system.
Deutsch, U, Deutsch, Urban, Deutsch U
core   +1 more source

Diabetes‐Associated Cognitive Impairment: Pathophysiology and Emerging Therapies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Diabetes‐associated cognitive impairment (DACI) is a common yet underrecognized condition, manifesting along a spectrum from mild cognitive impairment to dementia. DACI encompasses patients who develop vascular dementia (VaD) or Alzheimer's disease (AD) with diabetes as a risk factor; however, in certain patients, particularly those lacking ...
Osman Corbali, Priyanka Menon, Halil I. Corbali, Ram Jagannathan, Allan I. Levey   +4 more
wiley   +1 more source

Age-related variations in corneal endothelial cell density and morphology in a healthy Colombian adult population: A cross-sectional study

The Pan-American Journal of Ophthalmology
Purpose: The purpose of this study was to describe age-related variations in corneal endothelial cell density (ECD) and morphology in a healthy adult Colombian population.
Andrea Acosta-Ortega, Isabella Prieto-Avila, Katherine Perea-Gomez, Claudia Blanco, Guillermo Raul Vera-Duarte   +4 more
doaj   +1 more source

Downregulation of ETS rescues diabetes-induced reduction of endothelial progenitor cells [PDF]

, 2009
Background Transplantation of vasculogenic progenitor cells (VPC) improves neovascularization after ischemia. However, patients with type 2 diabetes mellitus show a reduced VPC number and impaired functional activity. Previously, we demonstrated that p38
Aicher Alexandra, Chen Linping, Seeger Florian Hartmut, Altschmied Joachim, Haendeler Judith, Alexandra Aicher, Aicher, Alexandra, Judith Haendeler, Seeger, Florian Hartmut, Chen, Linping, Haendeler, Judith, Florian Hartmut Seeger, Linping Chen, Joachim Altschmied, Spyridopoulos Ioakim, Spyridopoulos, Ioakim, Altschmied, Joachim, Ioakim Spyridopoulos   +17 more
core   +2 more sources