Results 251 to 260 of about 585,558 (296)

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Soft Ionic and Electronic Triboelectric Nanogenerators: Toward Attachable and Implantable Biomedical Applications

Advanced Materials, EarlyView.
This review provides an overview of triboelectric nanogenerator (TENG)–based biomedical applications by classifying studies into electronic and ionic systems across attachable and implantable platforms. It summarizes key material choices, device structures, and working mechanisms that characterize current TENG‐based research, and outlines six future ...
Kyongtae Choi, Jimin Park, Won Jun Song, Soohwan An, Seonggyu Choe, Byeong‐Rak Keum, Min Young Kim, Dae Hee Hwang, Young‐Geun Park, Sung‐Won Kim, Sangyul Baik, Gwang‐Bum Im, Younghoon Lee   +12 more
wiley   +1 more source

Non‐Invasive Brain Targeted Delivery of Cannabidiol for Alleviating Neuroinflammatory Disease

Advanced Materials, EarlyView.
The glucose‐functionalized nanoparticles (GNPs) are developed for the brain‐targeted delivery of cannabidiol (CBD). GNPs bypass the blood‐brain barrier (BBB) via glucose transporter‐1 (GLUT‐1) and release CBD in response to reactive oxygen species (ROS).
Yibin Wang, Yundong Li, Xin Wang, Yaning Hou, Wei Deng, Meng Zheng, Yan Zou, Bingyang Shi   +7 more
wiley   +1 more source

A Nano‐Interception Strategy for Chronic Heart Failure: Prussian Blue Nanoparticles Disrupt Fibroblast‐Immune Communication via CCL2 Sequestration

Advanced Materials, EarlyView.
A nano‐interception strategy disrupts pathogenic fibroblast–macrophage crosstalk in chronic heart failure. Scalable Prussian blue nanoparticles selectively sequester CCL2 via ultrahigh‐affinity binding, preventing CCR2+ macrophage recruitment and breaking a key fibro‐inflammatory circuit. This approach demonstrates robust efficacy in murine and porcine
Bo Chen, Gao Wei, Guowei Zeng, Haoyu Li, Rongrong Wu, Hongyu Yan, Zijie Zhou, Kai Luo, Xiaoyang Zhang, Cong Li, Longming Huang, Lingyan Cheng, Xinjie Zhang, Jinghao Zheng, Bozhong Shi, Xiaojun Cai, Xiaomin He   +16 more
wiley   +1 more source

Bioinspired, Mitochondria‐Targeted Single‐Atom Nanozyme Enhances Bone Regeneration by Reprogramming Stem Cell Energy Metabolism​

Advanced Materials, EarlyView.
A bioinspired nanozyme—triphenylphosphonium (TPP)‐dendritic mesoporous silica nanoparticle (DMSN)‐Fe/Cu—mimics mitochondrial complex IV and targets mitochondria to regulate cellular energy metabolism. This approach markedly boosts bone regeneration in vivo, as demonstrated by enhanced bone volume and mineral density in critical‐sized bone defects rat ...
Yuwen Wang, Xinzhi Liang, Tiandi Xiong, Zheng Zhong, Ning Zhang, Boguang Yang, Dong Li, Qiongjiao Zeng, Xian Chen, Yiting Lei, Shangsi Chen, Chao Zheng, Liu Yang, Wei Huang, Rocky S. Tuan, Denghui Xie, Zhong Alan Li   +16 more
wiley   +1 more source

Mechanically Spatio‐Chimeric Fibrin Assembly Enables Vascular‐Integrated Muscle Reconstruction for Volumetric Muscle Loss Repair

Advanced Materials, EarlyView.
SPARC (spatio‐chimeric, plasma‐based, anisotropic, and shear‐responsive construct) that integrates myogenic and vascular microenvironments within a single construct. The dual‐modulus matrix directs aligned myotube formation and endothelial network development, enabling a vascularized muscle implant that seamlessly anastomoses with host tissue and ...
Su Hyun Jung, Minjun Kim, Da‐Yoon Kim, Min Kyu Kim, Sieun Lee, Yoonhee Jin, Joo H. Kang   +6 more
wiley   +1 more source

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Preserflo MicroShunt: Efficacy and Endothelial Cell Density

Journal of Glaucoma, 2023
Précis: A main safety concern associated with new glaucoma implants is corneal endothelial cell loss, which could even be observed in already established procedures. Purpose: The purpose of this study was to evaluate the efficacy and corneal safety, especially corneal endothelial ...
Friedrich, Anton Steindor, Céline, Trigaux, Christoph, Holtmann, Kristina, Spaniol, Gerd, Geerling, Maria, Borrelli   +5 more
openaire   +2 more sources

Corneal endothelial cell density in patients receiving chemotherapy

Cutaneous and Ocular Toxicology, 2021
This study aimed to determine if the corneal endothelium was affected by chemotherapy.Chemotherapy patients were recruited to undergo specular microscopy before treatment and again at 1- and 2-year follow-up visits. One eye per patient, per follow-up, was selected for comparison to baseline.Forty-six volunteers completed baseline and at least one ...
Shawn P. Gallagher, Barton L. Halpern, Shanthi Sivendran   +2 more
openaire   +2 more sources

Corneal Endothelial Cell Density in Glaucoma

Cornea, 1997
We studied corneal endothelial cell density in patients with glaucoma.One hundred two patients with glaucoma were compared with 52 patients without glaucoma of the same age group. Exclusion criteria included history of either corneal disease, ocular inflammation, trauma, or surgery other than peripheral iridectomy.
M M, Gagnon, H M, Boisjoly, I, Brunette, M, Charest, M, Amyot   +4 more
openaire   +2 more sources

Postmortem Interval Estimation With Corneal Endothelial Cell Density

American Journal of Forensic Medicine & Pathology, 2021
Objectives In the neonatal period, healthy people have the highest corneal endothelial cell density (CECD) (5000–7000 cells/mm2). Corneal endothelial cell density declines with age in adults (2500–3000 cells/mm2) and continues to decline in the postmortem period. We measured CECD in cases with different postmortem interval (PMI)
AKYOL, MESUT, Özge, Gökhan, Balandiz, Hüseyin, Özsoy, Sait, Kaya, Burak, UYSAL, BETÜL SEHER, ÖZMEN, MEHMET CÜNEYT   +6 more
openaire   +4 more sources