Results 71 to 80 of about 1,223,204 (255)

Endothelial dysfunction: pathogenesis and treatment

, 2017
The endothelium plays a key role in vascular homeostasis through the release of a variety of autocrine and paracrine substances. Endothelial dysfunction can be defined as the partial or complete loss of balance between vasoconstrictors and vasodilators ...
Zeineh, Wissam
core  

Changes in Immune‐Inflammation Status and Prognosis in Pregnancy‐Related Cerebral Venous Thrombosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Distinguishing pathological changes from physiological adaptations in pregnancy‐related cerebral venous thrombosis (CVT) is clinically challenging. This study aimed to characterize coagulation, immune‐inflammation, and dehydration status in these patients and assess their prognostic value.
Xiaoming Zhang, Zilin Xu, Ran Duan, Chunxiao Lu, Da Zhou, Chen Zhou, Ran Meng, Xunming Ji   +7 more
wiley   +1 more source

Green Fluorescent Protein (GFP) color reporter gene visualizes parvovirus B19 Non-structural Segment 1 (NS1) transfected endothelial modification [PDF]

, 2012
Background: Human Parvovirus B19 (PVB19) has been associated with myocarditis putative due to endothelial infection. Whether PVB19 infects endothelial cells and causes a modification of endothelial function and inflammation and, thus, disturbance of ...
Seizer, Peter, Seizer Peter, Paul, Angela, Thomas Wurster, Botnar Rene M., Schönberger, Tanja, Stellos, Konstantinos L., Gawaz, Meinrad Paul, Tanja Schönberger, Gawaz Meinrad, Schuster Andreas, Gawaz, Meinrad, Botnar, Rene M.; id_orcid, Stellos, Konstantinos, Paul Angela, Boris Bigalke, Stellos Konstantinos, Pölzelbauer Catharina, Schönberger Tanja, Poelzelbauer, Catharina, Wurster, Thomas Heinrich, Angela Paul, Konstantinos Stellos, Meinrad Gawaz, Bigalke, Boris, Bigalke Boris, Botnar, Rene Michael, Rene M Botnar, Andreas Schuster, Wurster Thomas, Peter Seizer, Schuster, Andreas, Wurster, Thomas, Schoenberger, Tanja, Pölzelbauer, Catharina, Catharina Pölzelbauer   +35 more
core   +2 more sources

Age‐Dependent Predictive Value of Endothelial Dysfunction for Arrhythmia Recurrence Following Pulmonary Vein Isolation

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
Background The mechanisms of atrial fibrillation (AF) are highly divergent. The prevalence of AF increases significantly with age, and underling mechanisms might vary with age.
Yasushi Matsuzawa, Mahmoud Suleiman, Raviteja R. Guddeti, Taek‐Geun Kwon, Kristi H. Monahan, Lilach O. Lerman, Paul A. Friedman, Amir Lerman   +7 more
doaj   +1 more source

Endothelial dysfunction: pathogensis and treatment

, 2018
The causes of endothelial dysfunction, and how it contributes to many common diseases including hypertension and atherosclerosis. The medical and non-medical therapy of these conditions and what effect they have on the endothelium.
Khosravani, Sophie
core  

Insulin-stimulated phosphorylation of endothelial nitric oxide synthase at serine-615 contributes to nitric oxide synthesis [PDF]

, 2009
Insulin stimulates endothelial NO (nitric oxide) synthesis via PKB (protein kinase B)/Akt-mediated phosphorylation and activation of eNOS (endothelial NO synthase) at Ser-1177.
Boyd, Alasdair R., Stuart A. Ritchie, Ian P. Salt, Salt, Ian P., Kohlhaas, Christine F, Yalla, Krishna C, Kohlhaas, Christine F., Boyd, Alasdair R, Krishna C. Yalla, Walsh, Kenneth, Ritchie, Stuart A, John M. C. Connell, Christine F. Kohlhaas, Kenneth Walsh, Ritchie, Stuart A., Connell, John M.C., Connell, John Mc, Salt, Ian P, Alasdair R. Boyd, Yalla, Krishna C.   +19 more
core   +1 more source

Systemic Extracerebral Atherosclerotic Burden and Dementia Risk After Incident Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Stroke survivors are at increased risk of dementia, but clinically accessible markers of risk heterogeneity remain limited. Previous studies have largely examined atherosclerotic disease in individual vascular beds rather than the overall burden of systemic extracerebral atherosclerosis.
Zhexuan Yu, Tianxue Chen, Wei Jin, Weifeng Jin, Haitong Wan   +4 more
wiley   +1 more source

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

Arthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source

Endothelial dysfunction from a pharmacological point of view

, 2019
Endothelial cells that line the internal surface of the vasculature are a major regulator of vascular tone, inflammation, coagulation and platelet function.
Ali, Bashar Abed Alfattah Dyab
core  

Glu298Asp endothelial nitric oxide synthase gene polymorphism interacts with environmental and dietary factors to influence endothelial function [PDF]

, 2002
An endothelial nitric oxide synthase (eNOS) gene polymorphism (Glu298Asp) has been associated with cardiovascular disease. We investigated whether carriage of the polymorphism was associated with functional changes in the endothelium, and how genotype ...
Jeerooburkhan, N., Muller, D.P.R., Mullen, M.J., Deanfield, J.E., Muller, DP, Deanfield, JE, Humphries, SE, Kattenhorn, M., Cole, T.J., Lucas, A, Humphries, S.E., Leeson, Christopher, Kattenhorn, M, Hingorani, AD, Jeerooburkhan, N, Hingorani, S.D., Leeson, CP, Mullen, MJ, Leeson, C.P.M., Cole, TJ, Lucas, A.   +20 more
core   +1 more source