Results 221 to 230 of about 375,393 (288)

Nb2C‐Reinforced Hydrogel Microneedle as Dual ROS‐Scavenging Platform to Promote Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
An advanced microneedle patch integrating niobium carbide nanosheets and curcumin is engineered for diabetic wound healing. The system enables dual ROS scavenging and NIR‐enhanced antimicrobial activity, effectively rebalancing the oxidative microenvironment, promoting macrophage repolarization and angiogenesis, and accelerating full‐thickness wound ...
Zhi Zheng, Heyan Huang, Xiangru Chen, Jie Fu, Zhiwei Sun, Mengjuan Tao, Jianwei Mao, Fei Zhang, Zhou Wan, Yuan Li, Dingan Wu, Chuchao Zhou, Yanqing Yang   +12 more
wiley   +1 more source

Targeting Piezo1 can improve endometrial fibrosis by inhibiting ferroptosis in endothelial cells. [PDF]

iScience
Yang H, Dou C, Pan R, Xu Y, Zeng K, Huang J, Sun L, Yao Y, Wang J.   +8 more
europepmc   +1 more source

Electro‐Stimulated Graphene‐Polymer Nanocomposites Enable Wearable Patches With Feedback‐Controlled Drug Release

Advanced Healthcare Materials, EarlyView.
xx xx. ABSTRACT Stimuli‐responsive nanomaterials capable of spatiotemporal control over drug release are of nanocomposite patch (“e‐Medi‐Patch”) engineered from biodegradable polycaprolactone (PCL), graphene nanoplatelets, and a redox‐active therapeutic, niclosamide. The hierarchical composite integrates π‐π interactions between aromatic drug molecules
Santosh K. Misra, Ketan Dighe, Pranay Saha, Teresa Aditya, Muhammad S. Khan, Maha Alafeef, Parikshit Moitra, Dipanjan Pan   +7 more
wiley   +1 more source

3D electron microscopy reveals novel ultrastructural changes in the diabetic retinal neurovascular unit. [PDF]

Diabetologia
Albargothy MJ, Troendle EP, Laws R, Barabas P, Steel DHW, Taggart MJ, Curtis TM.   +6 more
europepmc   +1 more source

Mitochondrial Transplantation via Magnetically Responsive Artificial Cells Promotes Intracerebral Hemorrhage Recovery by Supporting Microglia Immunological Homeostasis

Advanced Materials, Volume 37, Issue 13, April 2, 2025.
A type of magnetically responsive artificial cells (ACs) has been developed, demonstrating the loading of mitochondria and self‐enclosure processes to ensure the protection of mitochondrial transport via the bloodstream. The treatment with ACs effectively transplanted mitochondria around the lesion, thereby improving neurological recovery by supporting
Mi Zhou, Jinhui Zang, Yuxuan Qian, Qiang Zhang, Yifan Wang, Tingting Yao, Hongyu Yan, Kai Zhang, Xiaojun Cai, Lixian Jiang, Yuanyi Zheng   +10 more
wiley   +1 more source

RAB5C Increases Endothelial Release of VWF by Regulating Vesicle Trafficking. [PDF]

Arterioscler Thromb Vasc Biol
Reventun P, Toledano-Sanz P, Delgado-Marin M, Viskadourou M, Foster DB, de Vries PS, Sabater-Lleal M, Alcharani N, Gonzalez-Cucharero C, Osburn WO, Morrison AC, Wolberg AS, Smith NL, Arvanitis M, Cohorts for Heart and Aging in Genomic Epidemiology Hemostasis Working Group, Lowenstein CJ.   +15 more
europepmc   +1 more source

Tunable Enhancement of T Cell Expansion Through Modulation of Stiffness and Adhesion Receptor Engagement in an Engineered Hydrogel Platform

Advanced Materials, EarlyView.
We develop a hydrogel scaffold with controlled substrate stiffness and ligand functionalization for cell culture. Stiff substrates presenting CD3/CD28/CD2 ligands induce 2000‐fold expansion of T cells; this is 68% greater than the clinical standard (Dynabeads) and the first hydrogel capable of large‐scale expansion. Although expanding at a lower yield,
Niroshan Anandasivam, Rabia Ali, Lordean Gustinvil, Matthew J. Rosenwasser, Iain E. Dunlop, Derfogail Delcassian   +5 more
wiley   +1 more source

Autoantibodies reactive with glomerular endothelial cells and podocytes in patients with membranous nephropathy. [PDF]

J Transl Autoimmun
Petr V, Purohit S, Poppelaars F, Renner B, Laskowski J, Whelan R, Kulik L, Kendrick J, Frazer-Abel A, Jalal D, Marcolin B, Schmelzer I, Debiec H, Ronco P, Saleem MA, Satchell SC, Thurman JM.   +16 more
europepmc   +1 more source

Rapid Fabrication of Self‐Propelled and Steerable Magnetic Microcatheters for Precision Medicine

Advanced Materials, EarlyView.
A rapid Joule heating fabrication method for the production of self‐propelling, adaptive microcatheters, with tunable stiffness and integrated microfluidic channels is presented. Demonstrated through three microrobotic designs, including a steerable guiding catheter, an untethered wave‐crawling TubeBot, and a distal‐end propelled microcatheter, it was ...
Zhi Chen, Boris Rivkin, David Castellanos‐Robles, Ivan Soldatov, Lukas Beyer, Mariana Medina‐Sánchez   +5 more
wiley   +1 more source

Single-Cell Metabolic Imaging Reveals Glycogen-Driven Adaptations in Endothelial Cells. [PDF]

Adv Sci (Weinh)
Chadha RS, Yang B, Yuan D, Kapelczak ED, Kocheril PA, Tapia A, Mahajan S, Colazo A, Malhi NK, Ambarian JA, Liu X, TeSlaa TA, Chen ZB, Wei L.   +13 more
europepmc   +1 more source