Results 71 to 80 of about 375,393 (288)
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
TNOA Journal of Ophthalmic Science and Research, 2018 Endothelial cell loss after penetrating keratoplasty leads to graft failure. The critical limit of the endothelial cell count for corneal decompensation is thought to be 700 cells/mm2.
Aruna Kumari R. Gupta +1 more
doaj +1 more source
Uterine spiral artery remodeling involves endothelial apoptosis induced by extravillous trophoblasts through Fas/FasL interactions. [PDF]
, 2005 Objective— Invasion of uterine spiral arteries by extravillous trophoblasts in the first trimester of pregnancy results in loss of endothelial and musculoelastic layers.
Ashton, SV +6 more
core +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Revista Cubana de Oftalmología, 2010 OBJETIVO: Determinar el estado del endotelio corneal mediante la microscopia óptica convencional, antes y después de la extracción extracapsular del cristalino o facoemulsificación.
Maurin A Francis Pérez +3 more
doaj
A novel method to analyze leukocyte rolling behavior
Biological Procedures Online, 2004 Leukocyte endothelial cell interaction is a fundamentally important process in many disease states. Current methods to analyze such interactions include the parallel-plate flow chamber and intravital microscopy.
Dunne Jessica L. +3 more
doaj +1 more source
Age and diabetes related changes of the retinal capillaries: an ultrastructural and immunohistochemical study [PDF]
, 2015 Normal human aging and diabetes are associated with a gradual decrease of cerebral flow in the brain with changes in vascular architecture. Thickening of the capillary basement membrane and microvascular fibrosis are evident in the central nervous system
ARTICO, Marco +10 more
core +1 more source
Specular Microscopy of Corneal Endothelial Cells in Cynomolgus Monkeys.
Journal of Veterinary Medical Science, 1994 The corneal endothelia of 15 male and 16 female cynomolgus monkeys (estimated age: 2 years and more) were examined with a contact-type specular microscope under general anesthesia. The specular microscopy showed uniform-sized, hexagonal endothelia arranged regularly on the innermost layer of the cornea.
H, Morita, K, Shimomura, Y, Sakuma
openaire +3 more sources
Reelin expression in brain endothelial cells: an electron microscopy study [PDF]
BMC Neuroscience, 2015 Reelin expression and function have been extensively studied in the brain, although its expression has been also reported in other tissues including blood. This raises the possibility that reelin might be able to cross the blood-brain barrier, which could be functionally relevant. Up-to-date no studies have been conducted to assess if reelin is present
Perez-Costas, Emma +2 more
openaire +2 more sources
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source