Results 91 to 100 of about 224,461 (347)

Activation of the Notch signaling pathway promotes neurovascular repair after traumatic brain injury

Neural Regeneration Research, 2015
The Notch signaling pathway plays a key role in angiogenesis and endothelial cell formation, but it remains unclear whether it is involved in vascular repair by endothelial progenitor cells after traumatic brain injury.
Qi-shan Ran, Yun-hu Yu, Xiao-hong Fu, Yuan-chao Wen   +3 more
doaj   +1 more source

eNOS transfection of adipose-derived stem cells yields bioactive nitric oxide production and improved results in vascular tissue engineering. [PDF]

, 2015
This study evaluates the durability of a novel tissue engineered blood vessel (TEBV) created by seeding a natural vascular tissue scaffold (decellularized human saphenous vein allograft) with autologous adipose-derived stem cells (ASC) differentiated ...
Bagameri, Gabor, Comeau, Jason, DiMuzio, Paul J., Faul, Elizabeth J, Fernandez, Sarah, Ferroni, Matthew, McIlhenny, Stephen, Policha, Aleksandra, Shapiro, Irving, Tulenko, Thomas, Zhang, Ping   +10 more
core   +2 more sources

The Floor‐Ceiling‐Chip, or 2 × 2D = Pseudo‐3D—Approaching 3D Cell Morphology and Organization between Two Opposing 2D Substrates with Cell‐Adhesive Protein Micropatterns

Advanced Healthcare Materials, EarlyView.
Here, we present a novel 3D cell patterning and culture platform. The “Floor‐Ceiling‐Chip” (FC‐Chip) consists of two opposing track‐etched membranes, creating a pseudo‐3D microenvironment for the cells in between. By providing the membranes with micropatterned cell‐adhesive islands of varying geometries and sizes, the FC‐Chip enables control over cell ...
Urandelger Tuvshindorj, Francesca Giacomini, Esra Güben Kaçmaz, Tim ten Brink, Lorenzo Moroni, Zeinab Tahmasebi Birgani, Clemens van Blitterswijk, Pamela Habibović, Stefan Giselbrecht, Jan de Boer, Roman Truckenmüller   +10 more
wiley   +1 more source

Classification and Functional Characterization of Vasa Vasorum-Associated Perivascular Progenitor Cells in Human Aorta

Stem Cell Reports, 2017
In the microcirculation, pericytes are believed to function as mesenchymal stromal cells (MSCs). We hypothesized that the vasa vasorum harbor progenitor cells within the adventitia of human aorta.
Marie Billaud, Vera S. Donnenberg, Bradley W. Ellis, E. Michael Meyer, Albert D. Donnenberg, Jennifer C. Hill, Tara D. Richards, Thomas G. Gleason, Julie A. Phillippi   +8 more
doaj   +1 more source

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

Advanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami, Yeonwoo Park, Seong Kyeong Jo, Min Hee Kim, Jae Hwang Song   +4 more
wiley   +1 more source

Mesenchymal adenomatous polyposis coli plays critical and diverse roles in regulating lung development. [PDF]

, 2015
BackgroundAdenomatous polyposis coli (Apc) is a tumor suppressor that inhibits Wnt/Ctnnb1. Mutations of Apc will not only lead to familial adenomatous polyposis with associated epithelial lesions, but will also cause aggressive fibromatosis in ...
Bellusci, Saverio, Chen, Hui, Chiu, Joanne, El Agha, Elie, Luo, Yongfeng, Menke, Douglas B, Qian, Bang-Ping, Shi, Wei, Turcatel, Gianluca, Warburton, David   +9 more
core   +1 more source

Characterization of an Injectable Poly(vinyl alcohol)‐gelatin Hydrogel for Growth Factor Delivery in an Orthopedic Application

Advanced Healthcare Materials, EarlyView.
This work introduces photo‐crosslinkable tyraminated poly(vinyl alcohol)‐gelatin (PVA‐GT) hydrogels as tunable injectable platforms for tissue engineering and growth factor delivery applications. This schematic illustrates the two developed hydrogel formulations and the experimental workflow used to evaluate their physico‐chemical properties in vitro ...
Alessia Longoni, Gretel S. Major, Sam Arnold, Samuel Tomkins, Eugenia Spessot, Scott Loeffler, Kieran Lau, Richard Tan, Jessica Harte, Roslyn Kemp, Tess Reynolds, Jelena Rnjak‐Kovacina, Gary J. Hooper, Tim B. F. Woodfield, David C. Kieser, Khoon S. Lim   +15 more
wiley   +1 more source

Influence of Rho Kinase Inhibitor Fasudil on Late Endothelial Progenitor Cells in Peripheral Blood of COPD Patients with Pulmonary Artery Hypertension

Biomolecules & Biomedicine, 2014
The objective of our work was to investigate the influence of Fasudil, a Rho inhibitor on the number and function of the late endothelial progenitor cells in peripheral blood of chronic obstructive pulmonary diseases (COPD) patients with pulmonary ...
Pei Liu, Hongmei Zhang, Yijun Tang, Chunfeng Sheng, Jianxin Liu, Yanjun Zeng   +5 more
doaj   +1 more source

Zebrafish Caudal Haematopoietic Embryonic Stromal Tissue (CHEST) Cells Support Haematopoiesis. [PDF]

, 2017
Haematopoiesis is an essential process in early vertebrate development that occurs in different distinct spatial locations in the embryo that shift over time.
Aggio, Julian, Campbell, Clyde, Marquez, Gabriel, Stachura, David L, Traver, David, Wolf, Anja, Wright, Francis   +6 more
core   +1 more source

Endothelial progenitor cells and atherosclerosis

Frontiers in Bioscience, 2013
Atherosclerosis is due to inflammation and endothelial dysfunction and damage caused by a variety of factors. Dysfunction of endothelial progenitor cells (EPCs) that differentiate into mature endothelial cell contributes to the development of atherosclerosis.
Changwu, Ruan, Yan, Shen, Rui, Chen, Zhancheng, Wang, Jin, Li, Yun, Jiang   +5 more
openaire   +2 more sources