Results 1 to 10 of about 115,640 (215)

Placental growth factor expression is required for bone marrow endothelial cell support of primitive murine hematopoietic cells. [PDF]

open access: yesPLoS ONE, 2013
Two distinct microenvironmental niches that regulate hematopoietic stem/progenitor cell physiology in the adult bone marrow have been proposed; the endosteal and the vascular niche.
Xiaoying Zhou   +2 more
doaj   +1 more source

Induction of Neurogenesis and Angiogenesis in a Rat Hemisection Spinal Cord Injury Model With Combined Neural Stem Cell, Endothelial Progenitor Cell, and Biomimetic Hydrogel Matrix Therapy

open access: yesCritical Care Explorations, 2021
OBJECTIVES:. Acute spinal cord injury is a devastating injury that may lead to loss of independent function. Stem-cell therapies have shown promise; however, a clinically efficacious stem-cell therapy has yet to be developed.
Eric J. Marrotte, DO, PhD   +6 more
doaj   +1 more source

Construction of a novel cell-free tracheal scaffold promoting vascularization for repairing tracheal defects

open access: yesMaterials Today Bio, 2023
Functional vascularization is crucial for maintaining the long-term patency of tissue-engineered trachea and repairing defective trachea. Herein, we report the construction and evaluation of a novel cell-free tissue-engineered tracheal scaffold that ...
Zhiming Shen   +15 more
doaj   +1 more source

Human intracardiac SSEA4+CD34- cells show features of cycling, immature cardiomyocytes and are distinct from Side Population and C-kit+CD45- cells.

open access: yesPLoS ONE, 2022
Cardiomyocyte proliferation has emerged as the main source of new cardiomyocytes in the adult. Progenitor cell populations may on the other hand contribute to the renewal of other cell types, including endothelial and smooth muscle cells.
Mikael Sandstedt   +8 more
doaj   +3 more sources

Pulmonary arterial hypertension in children with congenital heart disease: a deeper look into the role of endothelial progenitor cells and circulating endothelial cells to assess disease severity

open access: yesFrontiers in Pediatrics, 2023
Endothelial progenitor cells and circulating endothelial cells have been proposed as useful markers of severity and disease progression in certain vascular diseases, including pulmonary arterial hypertension. Our study focused on evaluating the levels of
Juan Calderón-Colmenero   +10 more
doaj   +1 more source

Does erythropoietin therapy affect circulating endothelial cells in hemodialysis patients?

open access: yesУкраїнський Журнал Нефрології та Діалізу, 2020
Anemia is a common complication of chronic kidney disease (CKD). The most common cause of anemia in CKD is erythropoietin deficiency; and the most important cause of mortality in CKD patients is atherosclerotic vascular complications which are ...
T. Bulduk   +7 more
doaj   +1 more source

Folic acid supplementation normalizes the endothelial progenitor cell transcriptome of patients with type 1 diabetes: a case-control pilot study

open access: yesCardiovascular Diabetology, 2009
Background Endothelial progenitor cells play an important role in vascular wall repair. Patients with type 1 diabetes have reduced levels of endothelial progenitor cells of which their functional capacity is impaired. Reduced nitric oxide bioavailability
Stubbs Andrew   +7 more
doaj   +1 more source

Endothelial progenitor cell-conditioned medium promotes angiogenesis and is neuroprotective after spinal cord injury

open access: yesNeural Regeneration Research, 2018
Endothelial progenitor cells secrete a variety of growth factors that inhibit inflammation, promote angiogenesis and exert neuroprotective effects. Therefore, in this study, we investigated whether endothelial progenitor cell-conditioned medium might ...
Tao Wang, Xiao Fang, Zong-Sheng Yin
doaj   +1 more source

Single-cell RNA sequencing based analysis depicts the development map of human early embryonic erythrocytes [PDF]

open access: yesJichu yixue yu linchuang, 2022
Objective Single-cell RNA sequencing (scRNA-seq) was used to systematically delineate the cell atlas and molecular tracks of human early erythroid development at the single-cell level.
CHEN Zhong-yang, MA Yan-ni, YU Jia
doaj   +1 more source

Endothelial progenitor cells in chronic obstructive pulmonary disease and emphysema.

open access: yesPLoS ONE, 2017
Endothelial injury is implicated in the pathogenesis of COPD and emphysema; however the role of endothelial progenitor cells (EPCs), a marker of endothelial cell repair, and circulating endothelial cells (CECs), a marker of endothelial cell injury, in ...
Margaret F Doyle   +13 more
doaj   +1 more source

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