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Endothelial Progenitor Cells [PDF]

open access: yesCirculation Research, 2004
Infusion of different hematopoietic stem cell populations and ex vivo expanded endothelial progenitor cells augments neovascularization of tissue after ischemia and contributes to reendothelialization after endothelial injury, thereby, providing a novel therapeutic option. However, controversy exists with respect to the identification and the origin of
Carmen Urbich, Stefanie Dimmeler
exaly   +4 more sources

Common endothelial progenitor cell assays identify discrete endothelial progenitor cell populations [PDF]

open access: yesAmerican Heart Journal, 2009
Multiple measures of endothelial progenitor cells (EPCs) have been described, but there has been limited study of the comparability of these assays. We sought to determine the reproducibility of and correlation between alternative EPC assay methodologies.We simultaneously assessed EPC numbers in 140 patients undergoing cardiac catheterization using the
Thomas J, Povsic   +5 more
openaire   +3 more sources

Endothelial Progenitor Cells [PDF]

open access: yesNew England Journal of Medicine, 2003
Vascular endothelial cells form a lining — one cell thick — for all the blood vessels in the body, providing a critical interface between the vessel itself and blood-borne elements.
Mihail, Hristov   +2 more
  +6 more sources

Endothelial Progenitor Cells [PDF]

open access: yesAnnual Review of Medicine, 2005
Endothelial progenitor cells are a circulating, bone marrow–derived cell population that appears to participate in both vasculogenesis and vascular homeostasis. Questions persist regarding their functional characteristics, as well as the precise panel of cell surface markers that uniquely define this newly described progenitor cell population.
Aarif Y, Khakoo, Toren, Finkel
openaire   +4 more sources

Placental growth factor expression is required for bone marrow endothelial cell support of primitive murine hematopoietic cells. [PDF]

open access: yesPLoS ONE, 2013
Two distinct microenvironmental niches that regulate hematopoietic stem/progenitor cell physiology in the adult bone marrow have been proposed; the endosteal and the vascular niche.
Xiaoying Zhou   +2 more
doaj   +1 more source

Induction of Neurogenesis and Angiogenesis in a Rat Hemisection Spinal Cord Injury Model With Combined Neural Stem Cell, Endothelial Progenitor Cell, and Biomimetic Hydrogel Matrix Therapy

open access: yesCritical Care Explorations, 2021
OBJECTIVES:. Acute spinal cord injury is a devastating injury that may lead to loss of independent function. Stem-cell therapies have shown promise; however, a clinically efficacious stem-cell therapy has yet to be developed.
Eric J. Marrotte, DO, PhD   +6 more
doaj   +1 more source

Endothelial progenitor cells in atherosclerosis [PDF]

open access: yesFrontiers in Bioscience, 2012
Endothelial progenitor cells (EPCs) are involved in the maintenance of endothelial homoeostasis and in the process of new vessel formation. Experimental and clinical studies have shown that atherosclerosis is associated with reduced numbers and dysfunction of EPCs; and that medications alone are able to partially reverse the impairment of EPCs in ...
Fuyong, Du   +8 more
openaire   +2 more sources

Construction of a novel cell-free tracheal scaffold promoting vascularization for repairing tracheal defects

open access: yesMaterials Today Bio, 2023
Functional vascularization is crucial for maintaining the long-term patency of tissue-engineered trachea and repairing defective trachea. Herein, we report the construction and evaluation of a novel cell-free tissue-engineered tracheal scaffold that ...
Zhiming Shen   +15 more
doaj   +1 more source

Endothelial progenitor cells in pregnancy [PDF]

open access: yesReproduction, 2007
Abstract The discovery of endothelial progenitor cells has generated considerable interest in the field of vascular biology. These cells arise from a population of circulating mononuclear cells and have the capacity to form new blood vessels and contribute to vascular repair. Circulating endothelial progenitor cell numbers are reduced
Amy O, Robb   +3 more
openaire   +2 more sources

Human intracardiac SSEA4+CD34- cells show features of cycling, immature cardiomyocytes and are distinct from Side Population and C-kit+CD45- cells.

open access: yesPLoS ONE, 2022
Cardiomyocyte proliferation has emerged as the main source of new cardiomyocytes in the adult. Progenitor cell populations may on the other hand contribute to the renewal of other cell types, including endothelial and smooth muscle cells.
Mikael Sandstedt   +8 more
doaj   +3 more sources

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