Results 1 to 10 of about 16,333 (259)

Neovascular Glaucoma from Ocular Ischemic Syndrome Treated with Serial Monthly Intravitreal Bevacizumab and Panretinal Photocoagulation: A Case Report [PDF]

Case Reports in Ophthalmological Medicine, 2022
Purpose. To describe a case of open-angle neovascular glaucoma (NVG) secondary to ocular ischemic syndrome (OIS) treated with a planned series of 6 monthly anti-VEGF injections with interspersed panretinal photocoagulation (PRP) sessions.
Hassaan Asif, Zhuangjun Si, Steven Quan, Pathik Amin, David Dao, Lincoln Shaw, Dimitra Skondra, Mary Qiu   +7 more
doaj   +2 more sources

Targeting ATF6 reduces pathological neovascularization and improves visual outcomes in retinal disease models [PDF]

Scientific Reports
Pathological retinal neovascularization is a cause of vision loss in diseases including retinopathy of prematurity (ROP), wet age-related macular degeneration (AMD), and diabetic retinopathy. The Unfolded Protein Response (UPR) is an intracellular signal
Allyssa Bradley, Soyoung Park, Soyeon Park, Kyle Kim, Angela Galdamez, Hyejung Min, Monica Sophia Diaz-Aguilar, M. Elizabeth Hartnett, Eun-Jin Lee, Jonathan H. Lin   +9 more
doaj   +2 more sources

Vascular Endothelial Growth Factor Signaling in Models of Oxygen-Induced Retinopathy: Insights Into Mechanisms of Pathology in Retinopathy of Prematurity

Frontiers in Pediatrics, 2021
Retinopathy of prematurity (ROP) is a leading cause of blindness in children worldwide. Blindness can occur from retinal detachment caused by pathologic retinal angiogenesis into the vitreous, termed intravitreal neovascularization (IVNV).
Aniket Ramshekar, M. Elizabeth Hartnett
doaj   +1 more source

TNF-alpha increases angiogenic potential in a co-culture system of dental pulp cells and endothelial cells [PDF]

Brazilian Oral Research, 2019
We recently demonstrated that a co-culture system of human umbilical vein endothelial cells (HUVECs) and human dental pulp stem cells (hDPSCs) could enhance angiogenesis ability in vitro.
Li AN, Shuai SHEN, Luyao WANG, Yong LI, Sidra FAHIM, Yumei NIU, Shuang PAN   +6 more
doaj   +1 more source

Physiological MRI of microvascular architecture, neovascularization activity, and oxygen metabolism facilitate early recurrence detection in patients with IDH-mutant WHO grade 3 glioma [PDF]

Neuroradiology, 2021
Abstract Purpose This study aimed to determine the diagnostic performance of physiological MRI biomarkers including microvascular perfusion and architecture, neovascularization activity, tissue oxygen metabolism, and tension for recurrence detection of IDH-mutant WHO grade 3 glioma. Methods
Andreas Stadlbauer, Gertraud Heinz, Stefan Oberndorfer, Max Zimmermann, Thomas M. Kinfe, Michael Buchfelder, Arnd Dörfler, Natalia Kremenevski, Franz Marhold   +8 more
openaire   +2 more sources

Angiogenic effects of cryosurgery with liquid nitrogen on the normal skin of rats, through morphometric study [PDF]

Anais Brasileiros de Dermatologia, 2014
BACKGROUND:Cryosurgery is an efficient therapeutic technique used to treat benign and malignant cutaneous diseases. The primary active mechanism of cryosurgery is related to vascular effects on treated tissue.
Camila Bianco Pimentel, Aparecida Machado de Moraes, Maria Letícia Cintra   +2 more
doaj   +2 more sources

Proangiogenic cells enhanced persistent and physiologic neovascularization compared with macrophages [PDF]

Experimental & Molecular Medicine, 2015
Proangiogenic cells (PACs) display surface markers and secrete angiogenic factors similar to those used by myelomonocytic cells, but, unlike myelomonocytic cells, PACs enhance neovascularization activity in experimental ischemic diseases. This study was performed to reveal the differential neovascularization activities of PACs compared with those of ...
Choi, Young-Eun, Cha, Young Ryun, Lee, Kyoung-min, Kim, Hyun Jin, Yoon, Chang-Hwan   +4 more
openaire   +2 more sources

Roles of lipocalin-type and hematopoietic prostaglandin D synthases in mouse retinal angiogenesis

Journal of Lipid Research, 2023
Normal angiogenesis is essential for retinal development and maintenance of visual function in the eye, and its abnormality can cause retinopathy and other eye diseases. Prostaglandin D2 is an anti-angiogenic lipid mediator produced by lipocalin-type PGD
Daiki Horikami, Erika Sekihachi, Keisuke Omori, Yui Kobayashi, Koji Kobayashi, Nanae Nagata, Kaori Kurata, Akiyoshi Uemura, Takahisa Murata   +8 more
doaj   +1 more source

VEGF164-mediated Inflammation Is Required for Pathological, but Not Physiological, Ischemia-induced Retinal Neovascularization [PDF]

The Journal of Experimental Medicine, 2003
Hypoxia-induced VEGF governs both physiological retinal vascular development and pathological retinal neovascularization. In the current paper, the mechanisms of physiological and pathological neovascularization are compared and contrasted. During pathological neovascularization, both the absolute and relative expression levels for VEGF164 increased to
Ishida, Susumu, Usui, Tomohiko, Yamashiro, Kenji, Kaji, Yuichi, Amano, Shiro, Ogura, Yuichiro, Hida, Tetsuo, Oguchi, Yoshihisa, Ambati, Jayakrishna, Miller, Joan, Gragoudas, Evangelos, Ng, Yin-Shan, D'Amore, Patricia, Shima, David T., Adamis, Anthony   +14 more
openaire   +5 more sources

Bone Marrow Origin of Endothelial Progenitor Cells Responsible for Postnatal Vasculogenesis in Physiological and Pathological Neovascularization [PDF]

Circulation Research, 1999
Abstract —Circulating endothelial progenitor cells (EPCs) have been isolated in peripheral blood of adult species. To determine the origin and role of EPCs contributing to postnatal vasculogenesis, transgenic mice constitutively expressing β-galactosidase under the transcriptional regulation of an endothelial cell–specific ...
T, Asahara, H, Masuda, T, Takahashi, C, Kalka, C, Pastore, M, Silver, M, Kearne, M, Magner, J M, Isner   +8 more
openaire   +2 more sources